Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
200-821-6
CAS no.:
74-90-8
Index number:
006-006-00-X, 006-006-01-7
Molecular formula:
CHN
SMILES:
C#N
InChI:
InChI=1S/CHN/c1-2/h1H
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
8
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is fatal if swallowed, is fatal in contact with skin, is fatal if inhaled, causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects and is an extremely flammable liquid and vapour.

This substance is covered by several Harmonised Classifications and Labelling's (CLH) entries approved by the European Union. Differentiating between the different CLH's entries requires manual verification. To know more about the CLH please visit the C&L Inventory.

Breakdown of all 310 C&L notifications submitted to ECHA

Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Acute Tox. 1 H310
Flam. Liq. 1 H224
Acute Tox. 1 H330
Acute Tox. 1 H300
STOT RE 1 H372
Acute Tox. 2 H300
Acute Tox. 2 H330
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 7 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.

This substance is used at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: wood preservation, controlling rodents by means other than repulsion or attraction, controlling insects, ants, etc. by means other than repulsion or attraction.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and transfer of chemicals at dedicated facilities.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; do not get in eyes, on skin, or on clothing; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a poison center or doctor/physician.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Alpha OR LIUK, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • AnQore B.V., Mauritslaan 49 6129 EL Urmond Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Evonik Antwerpen NV, Tijsmanstunnel West 2040 Antwerpen 4 Flanders Belgium
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • Lučební závody Draslovka a.s. Kolín, Havlíčkova 605 280 02 Kolín IV Czech Republic
  • Röhm GmbH, Deutsche-Telekom-Allee 9 64295 Darmstadt Germany
  • INEOS Nitriles (UK) Ltd (M & I), PO Box 62 Seal Sands TS2 1TX Middlesbrough United Kingdom

Substance names and other identifiers

HYDROCYANIC ACID, AQUEOUS SOLUTION (HYDROGEN CYANIDE, AQUEOUS SOLUTION) with not more than 20% hydrogen cyanide
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
Hydrogen cyanide
EC Inventory, Biocidal active substances, REACH pre-registration, Other, Occupational Exposure Limits - 4th list - Indicative OELVs, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels
Hydrogen cyanide
Biocidal active substances, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, Occupational Exposure Limits - 4th list - Indicative OELVs, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels
hydrogen cyanide ... %; hydrocyanic acid ... %
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
hydrogen cyanide ...% hydrocyanic acid ...%
C&L Inventory
hydrogen cyanide hydrocyanic acid
C&L Inventory
HYDROGEN CYANIDE, SOLUTION IN ALCOHOL with not more than 45% hydrogen cyanide
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
HYDROGEN CYANIDE, STABILIZED containing less than 3% water
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
hydrogen cyanide; hydrocyanic acid
Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
acid cianhidric acid cianhidric (ro)
C&L Inventory
acid cianhidric…% acid cianhidric…% (ro)
C&L Inventory
acido cianidrico cianuro di idrogeno (it)
C&L Inventory
Acidul cianhidric (ro)
Biocidal active substances
Cianeto de hidrogénio (pt)
Biocidal active substances
cianeto de hidrogénio ...% ácido cianídrico ...% (pt)
C&L Inventory
cianeto de hidrogénio ácido cianídrico (pt)
C&L Inventory
Cianuro de hidrógeno (es)
Biocidal active substances
cianuro di hidrógeno ...% ácido cianhídrico ...% (es)
C&L Inventory
Cianuro di idrogeno (it)
Biocidal active substances
cianuro di idrogeno ...% acido cianidrico ...% (it)
C&L Inventory
Cijanovodik (hr)
Biocidal active substances
Ciānūdeņradis (lv)
Biocidal active substances
ciānūdeņradis, ciānūdeņražskābe (lv)
C&L Inventory
cyanure d'hydrogène à ....%;acide hydrocyanique à …% (fr)
C&L Inventory
cyanure d'hydrogène;acide hydrocyanique (fr)
C&L Inventory
Cyanure d’hydrogène (fr)
Biocidal active substances
cyanväte ...% vätecyanid ...% (sv)
C&L Inventory
cyanväte vätecyanid (sv)
C&L Inventory
Cyjanowodór (pl)
Biocidal active substances
cyjanowodór kwas cyjanowodorowy (pl)
C&L Inventory
Hidrogén-cianid (hu)
Biocidal active substances
hidrogén-cianid ciánhidrogén sav (hu)
C&L Inventory
hidrogén-cianid …% ciánhidrogén sav …% (hu)
C&L Inventory
hydrogeencyanide (nl)
C&L Inventory
hydrogeencyanide ...% (nl)
C&L Inventory
Hydrogen cyanide (no)
Biocidal active substances
Hydrogencyanid (da)
Biocidal active substances
Hydrogencyanid (de)
Biocidal active substances
hydrogencyanid ... % blåsyre ... % (no)
C&L Inventory
hydrogencyanid ...% blåsyre ...% (da)
C&L Inventory
Hydrogencyanid ...% Cyanwasserstoff ...% (de)
C&L Inventory
hydrogencyanid blåsyre (da)
C&L Inventory
hydrogencyanid blåsyre (no)
C&L Inventory
Hydrogencyanid Cyanwasserstoff (de)
C&L Inventory
kwas cyjanowodorowy ...% kwas pruski ...% (pl)
C&L Inventory
Kyanovodík (cs)
Biocidal active substances
Kyanovodík (sk)
Biocidal active substances
kyanovodík kyselina kyanovodíková (cs)
C&L Inventory
kyanovodík kyselina kyanovodíková (sk)
C&L Inventory
kyanovodík …% kyselina kyanovodíková …% (cs)
C&L Inventory
kyanovodík … % kyselina kyanovodíková … % (sk)
C&L Inventory
syaanivety (fi)
C&L Inventory
syaanivety ...% (fi)
C&L Inventory
Vandenilio cianidas (lt)
Biocidal active substances
vandenilio cianidas ciano vandenilio rūgštis (lt)
C&L Inventory
vandenilio cianidas …% ciano vandenilio rūgštis …% (lt)
C&L Inventory
Vesiniktsüaniid Vesiniktsüaniidhape (et)
C&L Inventory
Vesiniktsüaniidh …% Vesiniktsüaniidhape …% (et)
C&L Inventory
Vesiniktsüaniidhape (et)
Biocidal active substances
Vetysyanidi (fi)
Biocidal active substances
Vodikov cianid (sl)
Biocidal active substances
vodikov cianid cianovodikova kislina (sl)
C&L Inventory
vodikov cianid...% cianovodikova kislina..% (sl)
C&L Inventory
Vätecyanid (sv)
Biocidal active substances
Waterstofcyanide (nl)
Biocidal active substances
ácido cianhídrico cianuro de hidrógeno (es)
C&L Inventory
Ċjanur tal-idroġenu (mt)
Biocidal active substances
Υδροκυάνιο (el)
Biocidal active substances
υδροκυάνιο ...% Υδροκυανικό οξύ ...% (el)
C&L Inventory
υδροκυάνιο Υδροκυανικό οξύ (el)
C&L Inventory
Водороден цианид (bg)
Biocidal active substances
хидроген цианид хидроцианова киселина (bg)
C&L Inventory
хидроген цианид...% хидроцианова киселина,...% (bg)
C&L Inventory
…% ciānūdeņradis …% ciānūdeņražskābe (lv)
C&L Inventory
cyanide
C&L Inventory, Registration dossier
formonitrile
C&L Inventory, Other
hydrocyanic acid
Registration dossier
Hydrocyanic acid
Registration dossier
hydrocyanic acid ...%
C&L Inventory
hydrogen cyanide
C&L Inventory, Biocidal active substances, Registration dossier
Hydrogen Cyanide
C&L Inventory, Registration dossier
hydrogen cyanide ...%
C&L Inventory
Blausaure
Registration dossier
Carbon hydride nitride (CHN)
Registration dossier
Cyanwasserstoff
Registration dossier
Cyclone B
Registration dossier
Evercyn
Registration dossier
Formic anammonide
Registration dossier
Formonitrile
Registration dossier
HCN
Registration dossier
Hydrocyanic acid
Registration dossier
Hydrocyanic acid (8CI, 9CI)
Registration dossier
Hydrogen Cyanide
Registration dossier
Prussic acid
Registration dossier
Uragan
Registration dossier
006-006-00-X
Index number
C&L Inventory
006-006-01-7
Index number
C&L Inventory
191234-22-7
CAS number
Other
341972-31-4
CAS number
Other
74-90-8
CAS number
EC Inventory, C&L Inventory, Biocidal active substances, Registration dossier, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, Occupational Exposure Limits - 4th list - Indicative OELVs, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Odour
Other (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 2 studies submitted
  • 2 studies processed
R Melting / freezing point
-13.24 °C @ 1.013 hPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Boiling point

Study results
  • 2 studies submitted
  • 2 studies processed
R Boiling point
25.7 °C @ 1 hPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.69 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
83 kPa @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 2 studies submitted
  • 2 studies processed
R Log Pow
-0.25 @ 20 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 2 studies submitted
  • 2 studies processed
R Water solubility (vol%)
100 vol% @ 20 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-17.8 °C @ 1 hPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 2 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
535 °C @ 1 hPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 2 studies processed
C Dissociating properties
Yes (100%) [2]
R Dissociation constant
9.36 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 2 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
0.192 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Inherently biodegradable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 2 studies submitted
  • 2 studies processed
R H - (pressure) m³/mol
13.48 Pa m³/mol @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Henry's law constant
13.48 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Study results
  • 2 studies submitted
  • 2 studies processed
% Distribution in Media:
R Air 91.31 % [2]
R Water 7.97 % [2]
R Soil 0.71 % [2]
R Sediment 0.01 % [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 5 µg/L (2)
Intermittent releases (freshwater) -
Marine water 1 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 50 µg/L (2)
Sediment (freshwater) -
Sediment (marine water) -
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 7 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 25 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 3 studies processed
P/RResults
EC50 (48 h) 130 µg/L [3]
EC50 (24 h) 270 µg/L [3]
NOEC (48 h) 76 µg/L [1]

Type of Study provided
Studies with data
Key study 1 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
LOEC (4 days) 160 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 780 µg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 54 µg/kg bw/day -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 130 µg/m³ repeated dose toxicity
Acute /short term: (DNEL) -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 18 µg/kg bw/day -
Acute /short term: (DNEL) -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 18 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 2 studies processed
P/RResults
LD50 3.62 mg/kg bw (rat) [2]
M/CInterpretations of results
Very toxic [2]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 6 studies submitted
  • 2 studies processed
M/CInterpretations of results
Very toxic [2]

inhalation
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 2.34 - 6.89 mg/kg bw (rabbit) [4]
M/CInterpretations of results
Very toxic [2]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 3.62 mg/kg bw
Inhalation route:
Adverse effect observed LC50 103 mg/m³
Dermal route:
Adverse effect observed LD50 2.34 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No study available
Eye
No study available
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No study available
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 8 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 12.5 - 140 mg/kg bw/day [6]
LOEL (rat): 40 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 8
Other
Data waiving
no waivers
Study data: inhalation
  • 8 studies submitted
  • 4 studies processed
P/RResults
NOAEC (rat): 57.7 ppm [2]
NOEC (rat): 9.2 ppm [2]
LOEC (rat): 29.9 ppm [2]

Study data: inhalation
Studies with data
Key study
Supporting study 4
Weight of evidence 4
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 13 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study 10
Weight of evidence 4
Other
Data waiving
no waivers
Study data: in vivo
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
No adverse effect observed NOAEL 7.9 mg/kg bw/day (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 4
Weight of evidence 2 7
Other
Data waiving
no waivers
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 12.5 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 10 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant