Brief Profile

Data platform availability banner - brief profile

Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-158-0
CAS no.:
7440-48-4
Index number:
027-001-00-9
Molecular formula:
Co
SMILES:
[Co]
InChI:
InChI=1S/Co
Type of substance:
Mono constituent substance
Origin:
Element
Registered compositions:
114
Of which contain:
49 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP14) approved by the European Union, this substance may cause cancer, may damage fertility, is suspected of causing genetic defects, may cause long lasting harmful effects to aquatic life, may cause an allergic skin reaction and may cause allergy or asthma symptoms or breathing difficulties if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is fatal if inhaled, may damage fertility and is suspected of damaging the unborn child, is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life, is harmful if swallowed, causes serious eye irritation and may cause damage to organs through prolonged or repeated exposure.

Breakdown of all 2808 C&L notifications submitted to ECHA

Skin Sens. 1 H317 Harmonised Classification
Acute Tox. 4 H302
Muta. 2 H341 Harmonised Classification
Resp. Sens. 1B H334
Repr. 1B H360Fd
Aquatic Chronic 4 H413 Harmonised Classification
Resp. Sens. 1 H334 Harmonised Classification
Eye Irrit. 2 H319
Acute Tox. 1 H330
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Aquatic Chronic 2 H411
Aquatic Chronic 3 H412
STOT RE 2 H373
Repr. 2 H361
https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (0.95% of REACH registrations).
  • M
Suspected to be Mutagenic (Harmonised C&L).
  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L).
  • R
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Toxic to Reproduction (0.95% of REACH registrations).
  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (0.95% of REACH registrations).
  • Sr
Officially recognised in the EU as Respiratory sensitising ( Harmonised C&L).
  • Sr
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Respiratory sensitising (0.95% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 100 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: metals and metal surface treatment products.

Other release to the environment of this substance is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting).

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles. This substance can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: metals.

This substance is used for the manufacture of: furniture.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), open transfer and processing with minerals/metals at elevated temperature and hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting).

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

This substance is used in the following products: metals, welding & soldering products, metal surface treatment products, coating products, inks and toners, pH regulators and water treatment products, laboratory chemicals, polymers and semiconductors. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders), transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following products: metals, metal surface treatment products, laboratory chemicals, semiconductors and pH regulators and water treatment products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals, fabricated metal products, electrical, electronic and optical equipment and metals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, the low energy manipulation of substances bound in materials or articles, handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders) and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, the low energy manipulation of substances bound in materials or articles and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation in materials and formulation of mixtures.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; in case of inadequate ventilation wear respiratory protection; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid release to the environment; use personal protective equipment as required.; do not handle until all safety precautions have been read and understood; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; avoid breathing the dust, fume, gas, mist, vapours or spray; wear respiratory protection; do not eat, drink or smoke when using this product; use only outdoors or in a well-ventilated area; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. If eye irritation persists get medical advice/attention. Get medical advice/attention if you feel unwell. Specific treatment is urgent (see label). Wash contaminated clothing before reuse. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If inhaled: if breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. If exposed or concerned: get medical advice/attention. If experiencing respiratory symptoms: call a poison center or doctor/physician. Immediately call a poison center or doctor/physician. Collect spillage. If skin irritation or a rash occurs: get medical advice/attention. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Follow specific treatment (see label). Rinse the mouth.

Storage statements

Store this substance locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AB Sandvik Coromant, Mossvägen 10 81181 Sandviken Sweden
  • Anthesis (Ireland) Limited 07, The Black Church St. Mary’s Place D07 P4AX Dublin Ireland
  • B-Lands Consulting (811244-6), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811558-0), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811726-5), 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811727-8), 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • BASF Nederland B.V., Velperplein 23 6811 AH Arnhem Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Belmet Handelsgesellschaft m.b.H., Gruberstraße 2-4 4020 Linz Austria
  • Betek GmbH & Co. KG, Sulgener Str. 21.23 78733 Aichhalden Germany
  • Brugger GmbH Magnetsysteme, Gewerbestr. 23 78739 Hardt Germany
  • Buss & Buss Spezialmetalle GmbH, Sassnitzer Strasse 10 18551 Sagard Germany
  • C&M Technologies GmbH, Gewerbepark Am Bahnhof 10+26 36456 Barchfeld-Immelborn Germany
  • Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemservice GmbH - (K9L4), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (T6A1), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
  • Concept Laser GmbH, Rudolf-Diesel-Str. 14 96215 Lichtenfels Germany
  • Concord Resources Europe B.V., Singel 250 1016AB Amsterdam Netherlands
  • Darton Commodities BV, Verlengde Slotlaan 12 3707 CG Zeist Netherlands
  • Dellas S.p.A., Via Pernisa 12 37023 Lugo di Grezzana Italy
  • Deloro Wear Solutions GmbH, Zur Bergpflege 51-53 56070 Koblenz Germany
  • DePuy (Ireland), Loughbeg NA Ringaskiddy County Cork Ireland
  • DURUM Verschleiß-Schutz GmbH, Carl-Friedrich-Benz-Strasse 7 47877 Willich Germany
  • Electro Optical Systems Finland Oy, Lemminkäisenkatu 36 20520 Turku Finland
  • ENRC Leasing B.V., Only Representative of Chambishi Metals PLC, Jan Luijkenstraat 8 bg 1071 Amsterdam Netherlands
  • Eramet S.A., 10 boulevard de Grenelle 75015 Paris France
  • ERASTEEL, Tour Maine Montparnasse 33 Avenue du Maine 75755 PARIS Cedex 15 France
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • F.I.L.M.S. S.p.A., Via Megolo, 43 28877 Anzola D'Ossola VB Italy
  • Forgital Italy S.p.A., Via Spezzapria 1 36010 Seghe di Velo d'Astico VI Italy
  • GE Avio S.r.l., via I Maggio 99 10040 Rivalta di Torino (TO) Italy
  • GE Hungary Ipari és Kereskedelmi Korlátolt Felelősségű Társaság, Váci út 77 1044 Budapest Hungary
  • Glencore Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Glencore International Import BV, Prinses Beatrixlaan 582 2595 BM Den Haag Netherlands
  • Glencore Nikkelverk AS, Vesterveien 31 4606 Kristiansand Norway
  • Global Tungsten & Powders spol. s r.o., Zahradni 46 79201 Bruntal Czech Republic
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • Grondmet GmbH & Co. KG, Luegallee 79 40545 Düsseldorf Germany
  • H.C. Starck Tungsten GmbH, Im Schleeke 78-91 38642 Goslar Germany
  • HH Compliance Ltd, Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland
  • HH Compliance Ltd., Rubicon Building, CIT Campus Bishopstown None Cork Ireland
  • Honeywell Aerospace Olomouc, s.r.o., Nádražní 400 783 65 Hlubočky - Mariánské Údolí Czech Republic
  • Howmet SAS (as OR Howmet Castings & Services Inc), 68/78 rue du moulin de cage 92230 Gennevilliers France
  • Hyperion Materials & Technologies (France) S.A.S., 625 route de la gare FR-26210 Epinouze France
  • Höganäs Belgium SA, Ruelle Gros Pierre 10 B-7800 Ath Belgium
  • Industrie-Rohstoffe GmbH, Beckmannsbusch 88 45133 Essen Germany
  • IXM B.V., Route de Lausanne 15 1201 GENEVA Geneva/Switzerland Netherlands
  • Jervois Finland Oy, PL 286 67101 Kokkola Finland
  • Johnson Matthey Chemicals GmbH, Wardstrasse 17 D-46446 Emmerich am Rhein Germany
  • Kennametal Italia Produzione S.R.L., Via Lombardia 32/F 20098 San Giuliano Milanese Italy
  • Kennametal Logistics GmbH, Zweibrücker Str. 105 66538 Neunkirchen Germany
  • Lipmann Walton Ireland Limited, c/o Crowleys DFK Unlimited Company 16/17 College Green D02 V078 Dublin Ireland
  • Luxcontrol S.A. (OR65), 1, Avenue des Terres Rouges 4331 Esch sur Alzette Luxembourg
  • M.P.I. Magneti Permanenti Industriali Srl, Via G. B. Vico, 25/b 20010 Cornaredo (MI) Italy
  • Magnequench GmbH, Österbergstraße 9 D - 72074 Tübingen Germany
  • MBR Metals, Vabaõhumuuseumi tee 1 13522 Tallinn Estonia
  • METRACO NV, Spinnerijkaai 45 / 203 8500 Kortrijk Belgium
  • Mitsui & Co. Europe Plc, Paris Branch., 112 Avenue Kleber 75116 Paris France
  • Neorem Magnets Oy, Friitalantie 5 FIN-28400 Ulvila Finland
  • Nilar AB, Bönavägen 55 80647 Gävle Sweden
  • Norilsk Nickel Harjavalta Oy(KOLA), Teollisuuskatu 1 FI-29200 Harjavalta Finland
  • Oerlikon Metco Europe GmbH, Am Prime Parc 2A 65479 Raunheim Hessen Germany
  • Oerlikon Metco WOKA GmbH, Im Vorwerk 25 36456 Barchfeld-Immelborn Germany
  • Only representative (No publishable name), null
  • ORIC SAS, 40 rue Claude Genin BP 2302 38033 Grenoble France France
  • Praxair Surface Technologies GmbH, Am Muehlbach 13 87487 Wiggensbach Germany
  • SAFT SAS, 26 Quai Charles Pasqua 92300 LEVALLOIS-PERRET France
  • SINTER SUD S.p.a., località capitone 82019 sant'agata dei goti bn Italy
  • Sitek Spikes GmbH, Sulgener Str. 19 - 23 78733 Aichhalden Germany
  • Smith & Nephew Orthopaedics GmbH, Alemannenstrasse 14 78532 Tuttlingen Germany
  • Sojitz Europe GmbH, Schirmerstr. 76 40211 Dusseldorf Germany
  • Specialty Metals Resources SA, Rue Tenbosch 42 A B 1050 Brussels Belgium
  • Specialty Metals Trading SA, Rue Tenbosch 42 A B 1050 Brussels Belgium
  • SPS International Ltd (OR to Caledonian Alloys Inc), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Cannon-Muskegon Corporation), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Huntington Alloys Corporation), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Special Metals New Hartford), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • SPS International Ltd (OR to Western Australian Specialty Alloys Pty. Ltd), Bays 122-125 Shannon Industrial Estate V14 TP27 Shannon Co. Clare Ireland
  • Stratton Metal Europe Limited, THE BLACK CHURCH ST. MARY'S PLACE D07 P4AX Dublin Ireland
  • TANIOBIS Smelting GmbH & Co. KG, Im Schleeke 78 -91 38642 Goslar Germany
  • ThyssenKrupp Schulte GmbH, ThyssenKrupp Allee 1 45143 Essen Germany
  • TODINI BV, Kleine Pathoekeweg 82 B-8000 Brugge Belgium
  • Trafigura Ventures V.B.V., Evert van de Beekstraat 1-82 The Base, Tower B, 5th floor 1118 CL Schiphol Netherlands
  • Traxys Europe SA, 19-21 Route Arlon same L-8009 Strassen Luxembourg Luxembourg
  • Umicore Finland Oy, Kobolttiaukio 1 67900 KOKKOLA Finland
  • Umicore NV/SA, Rue du Marais 31 1000 Brussels Belgium
  • Umicore Specialty Powders France, 54 Avenue RHIN et DANUBE 38000 GRENOBLE France
  • VACUUMSCHMELZE GmbH & Co. KG, Grüner Weg 37 D-63450 Hanau Germany
  • VARTA Microbattery GmbH, VARTA-Platz 1 73479 Ellwangen (Jagst) Germany
  • VDM Metals International GmbH, Plettenberger Str. 2 58791 Werdohl Germany
  • Wogen Resources Europe Limited, The Black Church St Mary's Place D07 P4AX Dublin Ireland
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Yordas GmbH, Äußere Nürnberger Straße 62 91301 Forchheim Germany
  • Engelhart CTP Services (UK) Limited, 4-19 Berkeley Square Berkeley Square House W1J 6BR London United Kingdom
  • ICoNiChem Widnes Ltd, Moss Bank Road WA8 0RU Widnes Cheshire United Kingdom
  • Jinchuan (Europe) Limited, 40 Craven Street WC2N 5NG London United Kingdom
  • LN Metals International Limited, 5th Floor, 20 Gracechurch Street EC3V 0BG LONDON United Kingdom
  • Mitsui & Co. Europe PLC London Branch, 1 St Martin's Le Grand EC1A 4AS London United Kingdom
  • momaja s.r.o., Karolinska 650/1 186 00 Prague 8 Czech Republic
  • Nickel and co s.r.l., Via Larga, 8 20122 Milano MI Italy
  • Norilsk Nickel Harjavalta Oy (POLAR), Teollisuuskatu 1 FI-29200 Harjavalta Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Sandvik Ltd, Manor Way B62 8QZ Halesowen West Midlands United Kingdom
  • SFP Metals (UK) Ltd, 49 Canterbury Inovation Centre University Road CT2 7FG Canterbury Kent United Kingdom
  • Smith & Nephew Orthopaedics Ltd, Smith & Nephew Orthopaedics Ltd Unit 1 SPA Park CV31 3HL Leamington SPA United Kingdom
  • Vale Europe Limited, Acton Refinery Bashley Road NW10 6SN London GB United Kingdom
  • Votorantim GmbH, Hubert Sattler Gasse 1, Suite 42 5020 Salzburg Austria Austria

Substance names and other identifiers

Cobalt
EC Inventory, C&L Inventory, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Fertilising Products Regulation, Annex III, Part II-Labelling, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex II - Restricted Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Cobalt
C&L Inventory, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Fertilising Products Regulation, Annex III, Part II-Labelling, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex II - Restricted Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
Cobalt (Co)
Fertilisers Regulation, Annex I, E.2.1, E.2.2 and E.2.3
Cobalt (de)
C&L Inventory
cobalt (fr)
C&L Inventory
cobalt (ro)
C&L Inventory
Cobalto (es)
C&L Inventory
cobalto (it)
C&L Inventory
cobalto (pt)
C&L Inventory
kobalt (cs)
C&L Inventory
Kobalt (da)
C&L Inventory
kobalt (hr)
C&L Inventory
kobalt (hu)
C&L Inventory
kobalt (mt)
C&L Inventory
kobalt (nl)
C&L Inventory
kobalt (pl)
C&L Inventory
kobalt (sk)
C&L Inventory
kobalt (sl)
C&L Inventory
kobaltas (lt)
C&L Inventory
kobalts (lv)
C&L Inventory
kobolt (sv)
C&L Inventory
Koboltti (fi)
C&L Inventory
koobalt (et)
C&L Inventory
κοβάλτιο (el)
C&L Inventory
кобалт (bg)
C&L Inventory
Co
C&L Inventory
COBALT
C&L Inventory, Registration dossier, Other
Cobalt
C&L Inventory, Registration dossier, Other
Cobalt (2+)
C&L Inventory
Cobalt 231-158-0
C&L Inventory
Cobalt metal
C&L Inventory, Registration dossier
Cobalt Metal
Registration dossier
Cobalt Powder
Registration dossier
Cobalt(2+)
C&L Inventory, Registration dossier
Cobalt, Cobolt
Registration dossier
cobalt-
C&L Inventory
Elemental cobalt in alloys
Registration dossier
Jinchuan (Europe) Limited
Registration dossier
kobalt
C&L Inventory
Reaction mass of iron and samarium and copper and zirconium
C&L Inventory
Cobalt
Registration dossier
Cobalt 1x1
Registration dossier
Cobalt 4x4
Registration dossier
Cobalt 90x90
Registration dossier
Cobalt cathodique fractions Fines US
Registration dossier
Cobalt Metal
Registration dossier
Cobalt off grade
Registration dossier
Cobalt off spec
Registration dossier
Cobalt Rounds
Registration dossier
Cobalt stripes
Registration dossier
K-1
Registration dossier
K-2
Registration dossier
K1 or K2
Registration dossier
K1A
Registration dossier
K1AY
Registration dossier
Norilsk K1A
Registration dossier
Norilsk K1AY
Registration dossier
027-001-00-9
Index number
C&L Inventory
1245817-40-6
CAS number
Other
1262528-32-4
CAS number
Other
132965-60-7
CAS number
Other
177256-35-8
CAS number
Other
184637-91-0
CAS number
Other
195161-79-6
CAS number
Other
335349-43-4
CAS number
Other
7440-48-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Fertilisers Regulation, Annex I, E.2.1, E.2.2 and E.2.3, Fertilising Products Regulation, Annex III, Part II-Labelling, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, FCM and Articles Regulation, Annex II - Restricted Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Compact (50%), Particulates (50%) [2]
C Odour
Odourless (100%) [2]
C Substance type
Element (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)
Form
Other (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 2 studies processed
R Melting / freezing point
1 493 - 1 495 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
1 494 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
2 927 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
2 927 °C

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Density
8.86 - 8.92 g/cm³ @ 20 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
8.89

Vapour pressure

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 8 studies submitted
  • 8 studies processed
R Water solubility (mass/vol.)
0 - 12 780 000 ng/L @ 20 - 37 °C and pH 5.81 - 8.61 [58]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
2.94 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 178 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 36
Supporting study 36 2
Weight of evidence
Other 2 102
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 66 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 9 1
Weight of evidence
Other 2 54
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 23 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1 3
Weight of evidence 4 14
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1.06 µg/L (1)
Intermittent releases (freshwater) -
Marine water 2.36 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 370 µg/L (1)
Sediment (freshwater) 53.8 mg/kg sediment dw (1)
Sediment (marine water) 69.8 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 10.9 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 27 studies submitted
  • 7 studies processed
P/RResults
LC50 (4 days) 1.512 - 85.3 mg/L [8]
NOEC (4 days) 656.8 - 100 000 µg/L [10]
LOEC (4 days) 1.43 - 88.7 mg/L [8]

Type of Study provided
Studies with data
Key study 7
Supporting study 6
Weight of evidence 1
Other 12 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 20 studies submitted
  • 7 studies processed
P/RResults
NOEC (81 days) 2.2 mg/L [5]
NOEC (34 days) 210 - 790 µg/L [3]
NOEC (33 days) 1.02 - 2.14 mg/L [3]
NOEC (28 days) 31.196 mg/L [3]
NOEC (7 days) 76.9 - 3 569.6 µg/L [36]

Type of Study provided
Studies with data
Key study 7
Supporting study 9
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 95 studies submitted
  • 40 studies processed
P/RResults
EC50 (4 days) 2.827 mg/L [1]
EC50 (72 h) 2.321 mg/L [1]
EC50 (48 h) 890 - 100 000 µg/L [5]
LC50 (7 days) 2.24 - 11.7 mg/L [2]
LC50 (4 days) 3.29 - 429 mg/L [3]

Type of Study provided
Studies with data
Key study 40
Supporting study 17
Weight of evidence
Other 37 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 16 studies processed
P/RResults
NOEC (3.767 months) 334.3 µg/L [1]
NOEC (42 days) 712.9 µg/L [1]
NOEC (30 days) 16.5 - 684.3 µg/L [12]
NOEC (28 days) 6.83 - 3 730 µg/L [9]
NOEC (21 days) 60.8 - 93.3 µg/L [2]

Type of Study provided
Studies with data
Key study 16
Supporting study 6
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 21 studies submitted
  • 7 studies processed
P/RResults
EC50 (7 days) 24.1 µg/L [1]
EC50 (4 days) 71.314 mg/L [1]
EC50 (72 h) 28.8 - 819.4 µg/L [21]
EC50 (70 h) 20 - 270 µg/L [2]
NOEC (7 days) 1.8 µg/L [1]

Type of Study provided
Studies with data
Key study 7
Supporting study 5
Weight of evidence
Other 9
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
310.4 µg/L
EC50 for marine water algae
24.1 µg/L
EC10 or NOEC for freshwater algae
76.4 µg/L
EC10 or NOEC for marine water algae
1.23 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 9 studies submitted
  • 3 studies processed
P/RResults
EC50 (7 days) 19.29 - 565.3 µg/L [13]
NOEC (7 days) 3 - 32.9 µg/L [13]
LOEC (7 days) 8.24 - 67.9 µg/L [13]
EC10 (7 days) 4.79 - 62.17 µg/L [13]
EC20 (7 days) 8.28 - 108.12 µg/L [12]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 6
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
52 µg/L
EC10 or NOEC for freshwater plants
10.4 µg/L

Toxicity to microorganisms

Study results
  • 9 studies submitted
  • 1 study processed
P/RResults
EC50 (30 min) 120 mg/L [1]
EC10 (30 min) 3.73 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 3 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
120 mg/L
EC10 or NOEC for microorganisms
3.73 mg/L

Sediment toxicity

Study results
  • 15 studies submitted
  • 11 studies processed
P/RResults
NOEC (42 days) 469 - 1 786.7 mg/kg sediment dw [6]
NOEC (28 days) 469 - 4 384 mg/kg sediment dw [12]
NOEC (28 days) 9.84 - 23.56 mg/L [6]
NOEC (10 days) 48.9 - 3 790 mg/kg sediment dw [39]
LOEC (42 days) 469 - 3 693.3 mg/kg sediment dw [6]

Type of Study provided
Studies with data
Key study 8
Supporting study
Weight of evidence 3
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater sediment
1 703 mg/kg sediment dw
EC10 / LC10 or NOEC for freshwater sediment
698 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 3 studies processed
P/RResults
NOEC (42 days) 868 - 1 091 mg/kg soil dw [2]
NOEC (28 days) 163 mg/kg soil dw [1]
EC10 (42 days) 51.5 - 145.4 mg/kg soil dw [4]
EC10 (28 days) 54.8 - 426 mg/kg soil dw [9]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
EC10 (28 days) 14.3 - 754 mg/kg soil dw [12]
NOEC (28 days) 100 - 1 000 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 15 studies submitted
  • 14 studies processed
P/RResults
NOEC (21 days) 9 - 34 mg/kg soil dw [3]
NOEC (4 days) 180 mg/kg soil dw [2]
EC10 (21 days) 8 - 617 mg/kg soil dw [39]
EC10 (14 days) 2.9 - 74.9 mg/kg soil dw [25]
EC10 (4 days) 13 - 255 mg/kg soil dw [10]

Type of Study provided
Studies with data
Key study 1 13
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 3 studies processed
P/RResults
NOEC (28 days) 120 mg/kg soil dw [1]
NOEC (24 h) 80 mg/kg soil dw [1]
EC10 (28 days) 36 - 4 685 mg/kg soil dw [8]
EC10 (7 days) 22 - 695 mg/kg soil dw [9]
EC10 (24 h) 6 - 602 mg/kg soil dw [9]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
50 mg/kg food

Toxicity to mammals

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (3.733 months) 200 mg/kg diet [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 54.1 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 40 µg/m³ repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 7.229 mg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.1 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 6.3 µg/m³ carcinogenicity
Acute /short term: High hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.265 mg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.9 µg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 52 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5
Supporting study 42
Weight of evidence
Other 5
Data waiving
no waivers
Study data: dermal absorption
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 4
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 550 mg/kg bw (rat) [1]
M/CInterpretations of results
Category 4 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 50 mg/m³ air (rat) [3]
M/CInterpretations of results
Category 1 based on GHS criteria [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 3 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [3]
M/CInterpretations of results
Not classified [3]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 550 mg/kg bw
Inhalation route:
Adverse effect observed LC50 50 mg/m³ air

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 19 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 3 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 15
Data waiving
no waivers
Study data: inhalation
  • 13 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 10
Weight of evidence
Other 3
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 50 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study
Weight of evidence 41
Other 9
Data waiving
no waivers
Study data: in vivo
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study 1
Weight of evidence 12
Other 2 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 11 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 13
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant