Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
262-104-4
CAS no.:
60207-90-1
Index number:
613-205-00-0
Molecular formula:
C15H17Cl2N3O2
SMILES:
CCCC1COC(CN2C=NC=N2)(O1)C1=CC=C(Cl)C=C1Cl
InChI:
InChI=1/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3
Type of substance:
Multi constituent substance
Origin:
Organic
Registered compositions:
2
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP13) approved by the European Union, this substance may damage the unborn child, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, is harmful if swallowed and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may damage fertility or the unborn child.

Breakdown of all 343 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Aquatic Chronic 1 H410 Harmonised Classification
Repr. 1B H360D
Repr. 1B H360
Eye Irrit. 2 H319
Repr. 2 H361
STOT RE 2 H373
Repr. 1A H360
Repr. 1B H360FD
Repr. 1B H360D Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • R
Officially recognised in the EU as Toxic to Reproduction (Harmonised C&L).
  • R
There is broad agreement in that a majority of data submitters agree this substance is Toxic to Reproduction (100% of REACH registrations).
  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).
  • ED
Under assessment as Endocrine Disrupting (ED list).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 3 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
This substance is subject to the Prior Informed Consent regulation and to export notification procedure from 01-Sep-2020
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

This substance is used in formulation or re-packing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: preservation films, wood preservation, preservation of fibres, leather, rubber, or polymers.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers and manual maintenance (cleaning and repair) of machinery.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid release to the environment; do not handle until all safety precautions have been read and understood; contaminated work clothing should not be allowed out of the workplace; avoid breathing the dust, fume, gas, mist, vapours or spray; do not eat, drink or smoke when using this product; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: call a poison center or doctor/physician if you feel unwell. Take off contaminated clothing and wash before reuse. If exposed or concerned: get medical advice/attention. Collect spillage. If on skin: wash with soap and water. Rinse the mouth.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Syngenta Hellas Single Member S.A.C.I., Anthousas Avenue 153 49 Anthousa-Attiki Greece

Substance names and other identifiers

1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
EC Inventory, Other
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
REACH pre-registration, Other
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole (Propiconazole)
Biocidal active substances
Propiconazole
PIC, Other, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, Statistics on Pesticides Regulation - Annex III Harmonized C&L, PIC Annex I, PIC Import notification,
Propiconazole (ISO)
Cosmetic Products Regulation, Annex II - Prohibited Substances
propiconazole(ISO); (2RS,4RS;2RS,4SR)-1-{[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
(±)-1-{[2-(2,4-dichlorfenyl)-4-propyl- 1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazol (propikonazol) (cs)
Biocidal active substances
1-[[2-(2,4-Dichloorfenyl)-4-propyl-1,3-dioxolaan-2-yl]methyl]-1H-1,2,4-triazool (propiconazool) (nl)
Biocidal active substances
1-[[2-(2,4-dichlorfenil)-4-propil-1,3-dioksolan-2-il]metil]-1H-1,2,4-triazolas (propikonazolas) (lt)
Biocidal active substances
1-[[2-(2,4-dichlorofenylo)-4-propylo- 1,3-dioksolan-2-ylo]metylo]-lH-1,2,4- triazol (propikonazol) (pl)
Biocidal active substances
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole (Propiconazole) (no)
Biocidal active substances
1-[[2-(2,4-dichlorophényl)-4-propyl-1,3-dioxolane-2-yl]méthyl]-1H-1,2,4-triazole (propiconazole) (fr)
Biocidal active substances
1-[[2-(2,4-dichlorphenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazol (propiconazol) (da)
Biocidal active substances
1-[[2-(2,4-Dichlorphenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazol (Propiconazol) (de)
Biocidal active substances
1-[[2-(2,4-dichlórfenyl)-4-propyl-1,3-dioxolán-2-yl]metyl]-1H-1,2,4-triazol (propikonazol) (sk)
Biocidal active substances
1-[[2-(2,4-diclorofenil)-4-propil-1,3-diossolan-2-il]metil]-1H-1,2,4-triazolo (Propiconazolo) (it)
Biocidal active substances
1-[[2-(2,4-Diclorofenil)-4-propil-1,3-dioxolan-2-il]metil]-1H-1,2,4-triazol (propiconazol) (es)
Biocidal active substances
1-[[2-(2,4-diclorofenil)-4-propil-1,3-dioxolan-2-il]metil]-1H-1,2,4-triazol (Propiconazol) (ro)
Biocidal active substances
1-[[2-(2,4-diclorofenil)-4-propil-1,3-dioxolan-2-il]metil]-1H-1,2,4-triazole (propiconazole) (pt)
Biocidal active substances
1-[[2-(2,4-Dihlorfenil)-4-propil-1,3-dioksolān-2-il]metil]-1H-1,2,4-triazols (propikonazols) (lv)
Biocidal active substances
1-[[2-(2,4-dikloorifenyyli)-4-propyyli-1,3-dioksolan-2-yyli]metyyli]-1H-1,2,4-triatsoli (propikonatsoli) (fi)
Biocidal active substances
1-[[2-(2,4-diklorofenil)-4-propil-1,3-dioksolan-2-il]metil]-1H-1,2,4-triazol (propikonazol) (hr)
Biocidal active substances
1-[[2-(2,4-diklorofenil)-4-propil-1,3-dioksolan-2-il]metil]-1H-1,2,4-triazol (propikonazol) (sl)
Biocidal active substances
1-[[2-(2,4-Diklorofenil)-4-propil-1,3-diossolan-2-il]metil]-1H-1,2,4-triażol (Propikonażol) (mt)
Biocidal active substances
1-[[2-(2,4-diklorofenyl)-4-propyl-1,3-dioxolan-2-yl]metyl]-1H-1,2,4-triazol (Propikonazol) (sv)
Biocidal active substances
1-[[2-(2,4-diklorofenüül)-4-propüül-1,3-dioksolaan-2-üül]metüül]-1H-1,2,4-triasool (propikonasool) (et)
Biocidal active substances
1-[[2-(2,4-diklórfenil)-4-propil-1,3-dioxolán-2-il]metil]-1H-1,2,4-triazol (Propikonazol) (hu)
Biocidal active substances
1-[[2-(2,4-διχλωροφαινυλο)-4-προπυλο-1,3-διοξολαν-2-υλο]μεθυλο]-1H-1,2,4-τριαζόλιο (Propiconazole/Προπικοναζόλη) (el)
Biocidal active substances
1-[[2-(2,4-дихлорофенил)-4-пропил-1,3-диоксолан-2-ил]метил]-1H-1,2,4-триазол (пропиконазол) (bg)
Biocidal active substances
propikonazol (ISO) (+)-1-(2-(2,4-diklórfenil)-4-propil-1,3-dioxolán-2-ilmetil]-1H-1,2,4-triazol (hu)
C&L Inventory
propikonazol (ISO) (+)-1-[2-(2,4-dichlorofenylo)-4-propylo-1,3-dioksolan-2-ylometylo]-1H-1,2,4-triazol (RS)-1-[2-(2,4-dichlorofenylo)-4-propylo-1,3-dioksolan-2-ylometylo]-1H-1,2,4-triazol (pl)
C&L Inventory
propikonazolas (ISO) (+)-1-[2-(2,4-dichlorfenil)-4-propil-1,3-dioksolan-2-ilmetil]-1H-1,2,4-triazolas (lt)
C&L Inventory
propikonazols (ISO) (+)-1-[2-(2,4-dihlorfenil)-4-propil-1,3-dioksolān-2-ilmetil]-1H-1,2,4-triazols (lv)
C&L Inventory
(+-)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
C&L Inventory
(2RS,4RS;2RS,4SR)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
C&L Inventory
(2RS,4RS;2RS,4SR)-1-{[2(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2yl]methyl}-1H-1,2,4-triazole
Registration dossier
(±)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
C&L Inventory
1-[2-(2,4-Dichlorophenyl)-4-n-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
C&L Inventory
1-[2-(2,4-Dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
C&L Inventory
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4- triazole
C&L Inventory
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole
Other
1-[[2-(2,4-Dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
C&L Inventory
1-{[2-(2,4-DICHLOROPHENYL)-4-PROPYL-1,3-DIOXOLAN-2-YL]METHYL}-1H-1,2,4-TRIAZOLE
C&L Inventory, Other
Propiconazole
C&L Inventory
Propiconazole
C&L Inventory, Registration dossier
propiconazole (ISO)
C&L Inventory
2934 99 90
CN Code
PIC, Other
2934 99 90
CN number
PIC
60207-90-1
CAS number
EC Inventory, C&L Inventory, PIC, Biocidal active substances, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Annexes II, III, IV, VII - Defined & Temporary Maximum Residue Levels, Statistics on Pesticides Regulation - Annex III Harmonized C&L, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work, PIC Annex I, PIC Import notification,
613-205-00-0
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Liquid: viscous (100%) [1]
C Odour
Sweetish (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)
Form
Liquid: viscous (100%)
Colour
colourless (100%)
Colour Intensity
transparent (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-23 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-23 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
99.9 °C @ 0.32 Pa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Density
1.289 g/cm³ @ 20 °C [1]
R Relative density
1.289 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.289

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
0 - 0 Pa @ 20 - 25 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Pow
4 500 @ 25 °C and pH 5.9 - 6.12 [1]
R Log Pow
3.7 @ 25 °C and pH 5.9 - 6.12 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
3.7 @ 25 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
110 mg/L @ 25 °C and pH 6.3 - 6.67 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
110 mg/L @ 25 °C

Solubility in organic solvents / fat solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 1 study processed
R Surface tension
55 mN/m @ 1.043 g/L and 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
55 mN/m @ 1 043 mg/L

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
200 °C @ 99.2 - 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
200 °C

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
430 °C @ 99.1 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
430 °C

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
GHS criteria not met (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
1.09 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
1.09

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R Other:
3.509 - 69.63 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
69 630 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
3.4 - 14 h [2]
R Degradation rate constant (OH radicals)
0 - 0 cm³ molecule-1 d-1 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
14 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 1 study processed
R Dissipation Half-life (DT50)
17.5 - 58.1 days [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in water
17.5 days

Phototransformation in soil

Study results
  • 3 studies submitted
  • 1 study processed
R Dissipation Half-life (DT50)
66 - 162 days [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in soil
5.4 months

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Under test conditions no biodegradation observed (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Not biodegradable (100%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in freshwater
78.29 days @ 20 °C
Half-life in freshwater sediment
1.521 years @ 20 °C

Biodegradation in soil

Study results
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in soil
68.3 days @ 20 °C

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
180 L/kg ww

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 2 studies processed
R Koc
382 - 1 817 L/kg @ 20 - 25 °C and 0.17 - 3.25 % organic carbon [9]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
950

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0 Pa m³/mol @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 18.8 µg/L (1)
Intermittent releases (freshwater) 43 µg/L (1)
Marine water 680 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 250 µg/kg sediment dw (1)
Sediment (marine water) 25 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 8.4 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 1.767 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 11 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 2.6 - 4.3 mg/L [2]
NOEC (4 days) 1 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 9
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
NOEC (8.533 months) 188 µg/L [1]
NOEC (3.333 months) 68 µg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 10.2 mg/L [1]
LC50 (4 days) 510 µg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 370 - 1 500 µg/L [2]
LOEC (21 days) 730 - 2 900 µg/L [2]
EC10 (21 days) 350 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 5 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 9 mg/L [1]
NOEC (72 h) 460 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
9 mg/L
EC10 or NOEC for freshwater algae
460 µg/L

Toxicity to aquatic plants other than algae

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater plants
9.02 mg/L
EC10 or NOEC for freshwater plants
2.94 mg/L

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (3 h) 100 mg/L [1]
NOEC (3 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (28 days) 25 - 50 mg/kg sediment dw [2]
NOEC (28 days) 4 - 8 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater sediment
25 mg/kg sediment dw

Endocrine disrupter testing in aquatic vertebrates – in vivo

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No summary exists for this scientific endpoint

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (56 days) 6.17 - 78.24 mg/kg soil dw [4]
EC10 (56 days) 2.99 - 11.7 mg/kg soil dw [2]
LC50 (14 days) 686.47 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
686.47 mg/kg soil dw
Long-term EC10 / LC10 / NOEC
2.99 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
LC50 (10 days) 500 mg/kg diet [1]
LD50 (10 days) 8.2 µg per animal per day [1]
LD50 (48 h) 100 µg per animal [2]
NOEC (10 days) 500 mg/kg diet [1]
NOED (10 days) 8.2 µg per animal per day [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 62.768 g/ha [1]
EC50 (21 days) 630 - 870 g/ha [4]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
840 µg/kg soil dw
Long-term EC10 / LC10 / NOEC
84 µg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (28 days) 1.66 mg/kg soil dw [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 11 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 10
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
300 mg/kg food

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.35 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 380 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 240 µg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 140 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 80 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 86 %
Dermal: 50 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 1 study processed
P/RResults
LD50 550 mg/kg bw (rat) [1]
M/CInterpretations of results
Category 4 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 5.836 mg/L air (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 3 studies submitted
  • 1 study processed
P/RResults
approx. LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 550 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 5.836 mg/L air
Dermal route:
No adverse effect observed Discriminating dose 5 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 240 - 1 500 ppm [3]
NOAEL (dog): 250 ppm [1]

Type of Study provided
Study data: oral
Studies with data
Key study 3
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 15.9 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 9
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 107.6 mg/kg bw/day (chronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
Adverse effect observed NOAEL 8.4 mg/kg bw/day (subchronic, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 30 mg/kg bw/day (subchronic, rat)

Neurotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant