carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.


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Group members
This group of substance has the following member substances:
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Name EC / List no. CAS no. Association
Beryllium orthosilicate 239-251-8 15191-85-2 Expert judgement
Copper alloy, Cu 96, Be 2.2-2.8, Ni 1.1 (CDA 827) - 11108-64-8 Expert judgement
Beryllium zinc silicate 247-151-0 25638-88-4 Expert judgement
Beryllium carbonate 236-030-8 13106-47-3 Expert judgement
Disodium tetrafluoroberyllate 237-630-2 13871-27-7 Expert judgement
Beryllium acetylide 208-050-7 506-66-1 Expert judgement
Beryllium nitrate 237-062-5 13597-99-4 Expert judgement
Aluminium alloy, Al,Be 603-236-8 12770-50-2 Expert judgement
Beryllium diboride 235-694-6 12536-51-5 Expert judgement
Octadecanoic acid, beryllium salt - 16687-38-0 Expert judgement
Beryllium diiodide 232-119-0 7787-53-3 Expert judgement
Beryllium chloride 232-116-4 7787-47-5 Expert judgement
Beryllium phosphide (BeP2) - 1268721-56-7 Expert judgement
Bertrandite (Be4(OH)2O(SiO3)2) 235-299-9 12161-82-9 Expert judgement
Beryllium phosphide 261-137-1 58127-61-0 Expert judgement
Beryllium di(acetate) 208-850-6 543-81-7 Expert judgement
Beryllium diboride 235-443-0 12228-40-9 Expert judgement
Nitric acid, beryllium salt, tetrahydrate 690-699-4 13510-48-0 Expert judgement
Beryllium diammonium tetrafluoride 238-948-4 14874-86-3 Expert judgement
Steel manufacture, chemicals
This category includes the chemical substances which are manufactured as part of steel and alloy steels. The following list identifies those elements which may exist in steel or which may comprise compounds present in steel or alloy steels. Aluminum, beryllium, boron, calcium, carbon, cerium, chromium, cobalt, copper, hafnium, iron, lanthanum, lead, magnesium, manganese, molybdenum, nickel, niobium, nitrogen, oxygen, phosphorus, selenium, silicon, sulfur, tantalum, tin, titanium, tungsten, vanadium, yttrium, zinc, zirconium.
266-048-1 65997-19-5 Expert judgement
Beryllium hydroxide 236-368-6 13327-32-7 Expert judgement
Beryllium hexaboride 235-657-4 12429-94-6 Expert judgement
Silicic acid, beryllium salt 261-293-0 58500-38-2 Expert judgement
Beryllium fluoride 232-118-5 7787-49-7 Expert judgement
Beryllium selenide 235-450-9 12232-25-6 Expert judgement
Hexakis[μ-(acetato-O:O')]-μ4-oxotetraberyllium 242-785-4 19049-40-2 Expert judgement
Bis(pentane-2,4-dionato-O,O')beryllium 233-513-5 10210-64-7 Expert judgement
Tetraberyllium boride 235-695-1 12536-52-6 Expert judgement
Beryllium telluride 235-451-4 12232-27-8 Expert judgement
Phosphoric acid, beryllium salt 252-356-3 35089-00-0 Expert judgement
Beryllium sulphate 236-842-2 13510-49-1 Expert judgement
Beryllium sulfate tetrahydrate 629-461-1 7787-56-6 Expert judgement
Diethylberyllium 208-823-9 542-63-2 Expert judgement
Triberyllium nitride 215-132-6 1304-54-7 Expert judgement
Beryllium sulphide 237-064-6 13598-22-6 Expert judgement
Beryllium dibromide 232-115-9 7787-46-4 Expert judgement
Zinc beryllium silicate - 39413-47-3 Expert judgement