EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 13 lipnja 2024. Database contains 4821 unique substances/entries.
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Carc. 1B
202-199-1
92-87-5
Carc. 1A; Acute Tox. 4
200-028-5
50-32-8
Carc. 1B; Muta. 1B; Repr. 1B; Skin Sens. 1
yes
205-892-7
192-97-2
Carc. 1B
205-883-8
191-24-2
yes
205-910-3
205-82-3
Carc. 1B
205-916-6
207-08-9
Carc. 1B
yes
205-877-5
189-55-9
Carc. 1B; Muta. 2
200-618-2
65-85-0
STOT RE 1; Skin Irrit. 2; Eye Dam. 1
431-600-4
112226-61-6
Skin Sens. 1
The distillate from coke oven light oil having an approximate distillation range below 100°C (212°F). Composed primarily of C4 to C6 aliphatic hydrocarbons.
266-023-5
65996-88-5
Carc. 1B; Muta. 1B
202-855-7
100-47-0
Acute Tox. 4
219-348-1
2421-28-5
Eye Irrit. 2; STOT SE 3
205-736-8
149-30-4
Skin Sens. 1
691-719-4
1072957-71-1
Acute Tox. 3
202-710-8
98-88-4
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
217-685-9
1929-88-0
Acute Tox. 4
B2,4DBB
420-710-8
23085-60-1
Repr. 2; Skin Irrit. 2; Skin Sens. 1
SQ 28,355; SQ 28355
416-050-5
87460-09-1
Eye Dam. 1
202-859-9
100-51-6
Acute Tox. 4
204-402-9
120-51-4
Acute Tox. 4
207-925-0
501-53-1
Skin Corr. 1B
204-262-9
118-58-1
Skin Sens. 1B
216-901-9
1694-09-3
Carc. 2
427-470-3
137864-22-3
Acute Tox. 4; Skin Sens. 1
B 2049
402-610-6
113694-52-3
Skin Corr. 1B; Acute Tox. 4
BM 96.0258.HCL
428-290-8
120606-08-8
Acute Tox. 4; Eye Dam. 1
202-854-1
100-46-9
Acute Tox. 4; Skin Corr. 1B
203-149-1
103-83-3
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
CA10
405-330-2
124088-59-1
Skin Irrit. 2; Eye Dam. 1
BONTRON P-51
402-240-5
102561-46-6
Acute Tox. 4
231-150-7
7440-41-7
Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
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Beryllium hydroxide EC / List no: 236-368-6 | CAS no: 13327-32-7
Copper alloy, Cu 96, Be 2.2-2.8, Ni 1.1 (CDA 827) EC / List no: - | CAS no: 11108-64-8
Beryllium selenide EC / List no: 235-450-9 | CAS no: 12232-25-6
Hexakis[μ-(acetato-O:O')]-μ4-oxotetraberyllium EC / List no: 242-785-4 | CAS no: 19049-40-2
Diethylberyllium EC / List no: 208-823-9 | CAS no: 542-63-2
Triberyllium nitride EC / List no: 215-132-6 | CAS no: 1304-54-7
Phosphoric acid, beryllium salt (2:3) EC / List no: - | CAS no: 13598-26-0
Beryllium diammonium tetrafluoride EC / List no: 238-948-4 | CAS no: 14874-86-3
Beryllium carbonate EC / List no: 236-030-8 | CAS no: 13106-47-3
Beryllium dibromide EC / List no: 232-115-9 | CAS no: 7787-46-4
Aluminium alloy, Al,Be EC / List no: 603-236-8 | CAS no: 12770-50-2
Beryllium nitrate trihydrate EC / List no: - | CAS no: 7787-55-5
Beryllium, bis(carbonato(2-))dihydroxytri- EC / List no: - | CAS no: 66104-24-3
Beryllium zinc silicate EC / List no: 247-151-0 | CAS no: 25638-88-4
Beryllium acetylide EC / List no: 208-050-7 | CAS no: 506-66-1
Beryllium hydrogen phosphate (1:1) EC / List no: - | CAS no: 13598-15-7
Beryllium di(acetate) EC / List no: 208-850-6 | CAS no: 543-81-7
Beryllium diiodide EC / List no: 232-119-0 | CAS no: 7787-53-3
Beryllium telluride EC / List no: 235-451-4 | CAS no: 12232-27-8
Beryllium chloride EC / List no: 232-116-4 | CAS no: 7787-47-5
Beryllium phosphide EC / List no: 261-137-1 | CAS no: 58127-61-0
Bertrandite (Be4(OH)2O(SiO3)2) EC / List no: 235-299-9 | CAS no: 12161-82-9
Beryllium oxyfluoride EC / List no: - | CAS no: 63990-88-5
Beryllium sulphide EC / List no: 237-064-6 | CAS no: 13598-22-6
Disodium tetrafluoroberyllate EC / List no: 237-630-2 | CAS no: 13871-27-7
Beryllium phosphide (BeP2) EC / List no: - | CAS no: 1268721-56-7
Tetraberyllium boride EC / List no: 235-695-1 | CAS no: 12536-52-6
Beryllium hexaboride EC / List no: 235-657-4 | CAS no: 12429-94-6
Silicic acid, beryllium salt EC / List no: 261-293-0 | CAS no: 58500-38-2
Beryllium orthosilicate EC / List no: 239-251-8 | CAS no: 15191-85-2
Zinc beryllium silicate EC / List no: - | CAS no: 39413-47-3
Beryllium sulfate tetrahydrate EC / List no: 629-461-1 | CAS no: 7787-56-6
Bis(pentane-2,4-dionato-O,O')beryllium EC / List no: 233-513-5 | CAS no: 10210-64-7
Beryllium nitrate EC / List no: 237-062-5 | CAS no: 13597-99-4
Nitric acid, beryllium salt, tetrahydrate EC / List no: 690-699-4 | CAS no: 13510-48-0
Steel manufacture, chemicals
This category includes the chemical substances which are manufactured as part of steel and alloy steels. The following list identifies those elements which may exist in steel or which may comprise compounds present in steel or alloy steels. Aluminum, beryllium, boron, calcium, carbon, cerium, chromium, cobalt, copper, hafnium, iron, lanthanum, lead, magnesium, manganese, molybdenum, nickel, niobium, nitrogen, oxygen, phosphorus, selenium, silicon, sulfur, tantalum, tin, titanium, tungsten, vanadium, yttrium, zinc, zirconium.
EC / List no: 266-048-1 | CAS no: 65997-19-5
Phosphoric acid, beryllium salt EC / List no: 252-356-3 | CAS no: 35089-00-0
Beryllium fluoride EC / List no: 232-118-5 | CAS no: 7787-49-7
Beryllium sulphate EC / List no: 236-842-2 | CAS no: 13510-49-1
Octadecanoic acid, beryllium salt EC / List no: - | CAS no: 16687-38-0
Beryllium diboride EC / List no: 235-694-6 | CAS no: 12536-51-5
Beryllium diboride EC / List no: 235-443-0 | CAS no: 12228-40-9
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Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
215-133-1
1304-56-9
Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
603-802-4
134237-51-7
yes
442-820-5
149877-41-8
STOT RE 2; Skin Sens. 1
617-373-6
82657-04-3
Carc. 2; Acute Tox. 3; Acute Tox. 2; STOT RE 1; Skin Sens. 1B
207-612-9
485-31-4
Repr. 1B; Acute Tox. 4
201-990-9
90-41-5
Carc. 2; Acute Tox. 4
202-110-6
91-95-2
Carc. 1B; Muta. 2
202-177-1
92-67-1
Carc. 1A; Acute Tox. 4
yes
202-163-5
92-52-4
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
PLR-22; XC95-A0638
414-960-7
53863-99-3
Acute Tox. 4
250-859-2
31895-22-4
Acute Tox. 4
EURENOR 5021; PSX 872
421-540-7
18230-61-0
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
TINUVIN 780
402-940-0
62782-03-0
Eye Irrit. 2
420-160-9
107667-02-7
Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
205-037-8
131-73-7
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
CGI 403
412-010-6
145052-34-2
Skin Sens. 1
205-594-7
143-24-8
Repr. 1B
yes
203-870-1
111-44-4
Carc. 2; Acute Tox. 2; Acute Tox. 1
221-201-1
3030-47-5
Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
DI(2-ETHYLHEXYL)DITHIODIGLYKOLAT; DP 327
404-510-8
62268-47-7
Acute Tox. 4; Skin Sens. 1
204-211-0
117-81-7
Repr. 1B
yes
430-700-5
10138-36-0
Skin Sens. 1
203-924-4
111-96-6
Flam. Liq. 3; Repr. 1B
yes
204-212-6
117-82-8
Repr. 1B
yes
BONTRON E-84; E-84
403-360-0
42405-40-3
Flam. Sol. 1; Acute Tox. 4
280-084-5
82985-35-1
Eye Dam. 1
DESMOPHEN VP-LS 2973 E; DESMOPHEN VP-LS 2975 E; DESMOPHEN VP-LS 2985 E
412-060-9
136210-32-7
Skin Sens. 1
404-420-9
71786-70-4
Skin Sens. 1
U 9649
401-380-4
89066-61-5
Eye Irrit. 2
200-237-1
55-55-0
Acute Tox. 4; STOT RE 2; Skin Sens. 1
INTEROX-PMBP-70W; INTEROX-PMPB-70W
407-950-9
895-85-2
Org. Perox. B
205-137-1
134-31-6
Acute Tox. 4
208-832-8
542-88-1
Flam. Liq. 2; Carc. 1A; Acute Tox. 2; Acute Tox. 3; Acute Tox. 4
276-205-6
71957-07-8
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Z-27
421-660-1
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Eye Dam. 1; Skin Sens. 1
418-370-0
143925-92-2
Skin Sens. 1
233-118-8
10039-54-0
Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
SAFRANIN SHMN
406-770-8
149057-64-7
STOT RE 2; Eye Dam. 1; Skin Sens. 1
608-595-4
312600-89-8
Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
239-703-4
15627-09-5
Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
GR101655A
423-170-1
618-26-8
Flam. Liq. 2; STOT RE 1; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
214-604-9
1163-19-5
yes
202-328-1
94-37-1
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
200-268-0
56-35-9
yes
201-279-3
80-43-3
Org. Perox. F; Repr. 1B; Skin Irrit. 2; Eye Irrit. 2
CGI 784
412-000-1
125051-32-3
Flam. Sol. 1; Repr. 2; STOT RE 2
421-560-6
-
STOT RE 2; Eye Dam. 1
216-823-5
1675-54-3
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
TK 10891; XB 4458; XW 528; ZK XB 4458
405-635-0
-
Skin Irrit. 2; Eye Dam. 1
VECTOMER E2200
413-930-0
130066-57-8
Skin Sens. 1
TITANCHELAT ETAM
410-500-4
357921-97-2
Eye Dam. 1
MCP-304
415-210-1
160236-81-7
Acute Tox. 4; Eye Dam. 1
201-245-8
80-05-7
Repr. 1B; STOT SE 3; Eye Dam. 1; Skin Sens. 1
yes
-
90568-23-3
yes
-
125022-34-6
yes
616-932-1
8011-63-0
Acute Tox. 4; Eye Dam. 1
234-343-4
11113-50-1
Repr. 1B
yes
233-139-2
10043-35-3
Repr. 1B
yes
-
22454-04-2
yes
-
14890-53-0
yes
-
25747-83-5
yes
215-604-1
1333-73-9
yes
233-657-9
10294-33-4
Acute Tox. 2; Skin Corr. 1A
233-658-4
10294-34-5
Press. Gas; Acute Tox. 2; Skin Corr. 1B
231-569-5
7637-07-2
Press. Gas; Acute Tox. 2; Skin Corr. 1A
249-205-9
28772-56-7
Repr. 1B; Acute Tox. 1; STOT RE 1
232-572-4
9001-00-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1

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