EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 20 rujna 2024. Database contains 4821 unique substances/entries.
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214-215-4
1114-71-2
Acute Tox. 4
234-390-0
11138-47-9;12040-72-1;37244-98-7
yes
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
yes
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
Repr. 1B; STOT SE 3; Eye Dam. 1
234-390-0
11138-47-9;12040-72-1;37244-98-7
yes
LI-BIT
411-690-1
111337-53-2
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
-
11132-10-8
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
214-197-8
1113-02-6
Acute Tox. 3; Acute Tox. 4
TACS
403-690-5
111298-82-9
Resp. Sens. 1; Skin Sens. 1
234-363-3
11120-22-2
yes
234-349-7
11113-75-0
Carc. 1A; Muta. 2; STOT RE 1; Skin Sens. 1
234-348-1
11113-74-9
Carc. 1A; Repr. 1B; Muta. 2; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
234-343-4
11113-50-1
Repr. 1B
yes
234-329-8
11103-86-9
yes
203-924-4
111-96-6
Flam. Liq. 3; Repr. 1B
yes
203-921-8
111-92-2
Flam. Liq. 3; Acute Tox. 4
203-906-6
111-77-3
Repr. 2
203-905-0
111-76-2
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
203-892-1
111-65-9
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
203-874-3
111-48-8
Eye Irrit. 2
203-872-2
111-46-6
Acute Tox. 4
203-870-1
111-44-4
Carc. 2; Acute Tox. 2; Acute Tox. 1
203-869-6
111-43-3
Flam. Liq. 2; STOT SE 3
203-868-0
111-42-2
Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
203-867-5
111-41-1
Repr. 1B; Skin Corr. 1B; Skin Sens. 1
203-865-4
111-40-0
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
203-856-5
111-30-8
Acute Tox. 2; Acute Tox. 3; STOT SE 3; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1A
yes
203-852-3
111-27-3
Acute Tox. 4
203-839-2
111-15-9
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
yes
203-838-7
111-14-8
Skin Corr. 1B
234-323-5
11099-02-8
Carc. 1A; STOT RE 1; Skin Sens. 1
TRIAZAMATE
411-650-3
110895-43-7
Acute Tox. 3
2-CHLORO-4,5-DIFLUORO BENZOIC ACID; BA-6; CDFBA
405-380-5
110877-64-0
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
COMPIMIDE™ 121
405-840-5
110866-35-8
Skin Sens. 1
VULKANISATIONSBESCHLEUNIGER VP KA 9124
404-380-2
110799-28-5
Skin Sens. 1
234-290-7
11070-44-3
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
234-284-4
11066-49-2
yes
404-200-2
110488-70-5
Repr. 1B
TTP MAGENTA 3
405-480-9
110260-50-9
Acute Tox. 4; STOT RE 2; Skin Irrit. 2
432-140-7
110235-47-7
Carc. 2
701-225-3
1101132-67-5
Carc. 2; Repr. 2; STOT RE 2
234-239-9
11005-63-3
Acute Tox. 3; STOT RE 2
429-620-3
110028-14-3
Skin Irrit. 2; Skin Sens. 1
203-820-9
110-97-4
Eye Irrit. 2
203-815-1
110-91-8
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
203-813-0
110-89-4
Flam. Liq. 2; Acute Tox. 3; Skin Corr. 1B
203-812-5
110-88-3
Flam. Sol. 1; Repr. 2; STOT SE 3
203-809-9
110-86-1
Flam. Liq. 2; Acute Tox. 4
203-808-3
110-85-0
Repr. 2; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
203-808-3
110-85-0
Repr. 2; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
203-806-2
110-82-7
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
203-804-1
110-80-5
Flam. Liq. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4
yes
203-798-0
110-74-7
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
203-794-9
110-71-4
Flam. Liq. 2; Repr. 1B; Acute Tox. 4
yes
203-792-8
110-69-0
Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2
203-788-6
110-65-6
Skin Corr. 1B; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1
203-777-6
110-54-3
Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; STOT SE 3
203-772-9
110-49-6
Repr. 1B; Acute Tox. 4
yes
203-770-8
110-46-3
Flam. Liq. 2; Acute Tox. 4
203-769-2
110-45-2
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
203-767-1
110-43-0
Flam. Liq. 3; Acute Tox. 4
203-745-1
110-19-0
Flam. Liq. 2
203-744-6
110-18-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1B
203-743-0
110-17-8
Eye Irrit. 2
203-742-5
110-16-7
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
203-737-8
110-12-3
Flam. Liq. 3; Acute Tox. 4
203-733-6
110-05-4
Org. Perox. E; Flam. Liq. 2; Muta. 2
203-728-9
110-01-0
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
203-727-3
110-00-9
Flam. Liq. 1; Carc. 1B; Muta. 2; Acute Tox. 4; STOT RE 2; Skin Irrit. 2
yes
BRL 44742
415-550-0
109887-53-8
Acute Tox. 4; Eye Dam. 1
FR-1034
408-020-5
109678-33-3
Skin Sens. 1
432-750-3
109202-58-6
Carc. 1B; Muta. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
BLEU DIOXAZINA ST 7005; BLEU DIOXAZINE ST 7005; DIOXAZIN BLAU ST 7005; DIOXAZINE BLUE ST 7005
402-590-9
109125-56-6
Eye Dam. 1
AIZEN SPILON BLACK TRH; AIZEN SPILON SCHWARZ TRH; THR-1; TRH
400-110-2
109125-51-1
Self-react. C
TILCOM CA35; TILCOM IA10; TYTAN AP 100; TYTAN CA 100; TYTAN CX 35; TYZOR IAM
401-100-0
109037-78-7
Flam. Liq. 2; Eye Irrit. 2
203-726-8
109-99-9
Flam. Liq. 2; Carc. 2; Eye Irrit. 2; STOT SE 3
203-722-6
109-95-5
Flam. Gas 1; Press. Gas; Acute Tox. 4
203-721-0
109-94-4
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
203-716-3
109-89-7
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
203-713-7
109-86-4
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
yes
203-710-0
109-83-1
Acute Tox. 4; Skin Corr. 1B
203-703-2
109-77-3
Acute Tox. 3
203-700-6
109-74-0
Flam. Liq. 2; Acute Tox. 3
203-699-2
109-73-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
203-696-6
109-69-3
Flam. Liq. 2
203-692-4
109-66-0
Flam. Liq. 2; Asp. Tox. 1; STOT SE 3
203-687-7
109-61-5
Flam. Liq. 2; Acute Tox. 3; Skin Corr. 1B
203-686-1
109-60-4
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
203-685-6
109-59-1
Acute Tox. 4; Eye Irrit. 2
203-680-9
109-55-7
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
203-677-2
109-52-4
Skin Corr. 1B
203-656-8
109-21-7
Flam. Liq. 3
203-643-7
109-06-8
Flam. Liq. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
DUASYN DIREKTSCHWARZ HEF-SF VP 332
411-890-9
108936-08-9
Acute Tox. 4; Eye Dam. 1
UC-129
403-790-9
108673-51-4
Skin Sens. 1

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