EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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Prikazano 1.601 - 1.700 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
benzyl chloroformate	207-925-0	501-53-1	Skin Corr. 1B
benzyl salicylate	204-262-9	118-58-1	Skin Sens. 1B
benzyl violet 4B; α-[4-(4-dimethylamino-α-{4-[ethyl(3-sodiosulphonato benzyl)amino] phenyl}benzylidene)cyclohexa-2,5-dienylidene(ethyl)ammonio]toluene-3-sulphonate	216-901-9	1694-09-3	Carc. 2
benzyl(S)-2-[(2'-cyanobiphenyl-4-ylmethyl)pentanoylamino]-3-methylbutyrate	427-470-3	137864-22-3	Acute Tox. 4; Skin Sens. 1
benzyl-2-hydroxydodecyldi; methylammonium benzoate B 2049	402-610-6	113694-52-3	Skin Corr. 1B; Acute Tox. 4
benzyl-N-(2-(2-methoxyphenoxy)ethyl)amine hydrochloride BM 96.0258.HCL	428-290-8	120606-08-8	Acute Tox. 4; Eye Dam. 1
benzylamine	202-854-1	100-46-9	Acute Tox. 4; Skin Corr. 1B
benzyldimethylamine	203-149-1	103-83-3	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
benzyldimethyloctadecylammonium 3-nitrobenzenesulfonate CA10	405-330-2	124088-59-1	Skin Irrit. 2; Eye Dam. 1
benzyltributylammonium 4-hydroxynaphthalene-1-sulphonate BONTRON P-51	402-240-5	102561-46-6	Acute Tox. 4
beryllium	231-150-7	7440-41-7	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
beryllium compounds with the exception of aluminium beryllium silicates, and with those specified elsewhere in this Annex show/hide Beryllium acetylide EC / List no: 208-050-7 \| CAS no: 506-66-1 Disodium tetrafluoroberyllate EC / List no: 237-630-2 \| CAS no: 13871-27-7 Beryllium sulfate tetrahydrate EC / List no: 629-461-1 \| CAS no: 7787-56-6 Beryllium carbonate EC / List no: 236-030-8 \| CAS no: 13106-47-3 Beryllium diboride EC / List no: 235-694-6 \| CAS no: 12536-51-5 Beryllium selenide EC / List no: 235-450-9 \| CAS no: 12232-25-6 Beryllium chloride EC / List no: 232-116-4 \| CAS no: 7787-47-5 Beryllium nitrate EC / List no: 237-062-5 \| CAS no: 13597-99-4 Beryllium hydroxide EC / List no: 236-368-6 \| CAS no: 13327-32-7 Nitric acid, beryllium salt, tetrahydrate EC / List no: 690-699-4 \| CAS no: 13510-48-0 Beryllium zinc silicate EC / List no: 247-151-0 \| CAS no: 25638-88-4 Octadecanoic acid, beryllium salt EC / List no: - \| CAS no: 16687-38-0 Beryllium phosphide EC / List no: 261-137-1 \| CAS no: 58127-61-0 Beryllium nitrate trihydrate EC / List no: - \| CAS no: 7787-55-5 Steel manufacture, chemicals This category includes the chemical substances which are manufactured as part of steel and alloy steels. The following list identifies those elements which may exist in steel or which may comprise compounds present in steel or alloy steels. Aluminum, beryllium, boron, calcium, carbon, cerium, chromium, cobalt, copper, hafnium, iron, lanthanum, lead, magnesium, manganese, molybdenum, nickel, niobium, nitrogen, oxygen, phosphorus, selenium, silicon, sulfur, tantalum, tin, titanium, tungsten, vanadium, yttrium, zinc, zirconium. EC / List no: 266-048-1 \| CAS no: 65997-19-5 Tetraberyllium boride EC / List no: 235-695-1 \| CAS no: 12536-52-6 Copper alloy, Cu 96, Be 2.2-2.8, Ni 1.1 (CDA 827) EC / List no: - \| CAS no: 11108-64-8 Phosphoric acid, beryllium salt (2:3) EC / List no: - \| CAS no: 13598-26-0 Beryllium sulphide EC / List no: 237-064-6 \| CAS no: 13598-22-6 Phosphoric acid, beryllium salt EC / List no: 252-356-3 \| CAS no: 35089-00-0 Beryllium fluoride EC / List no: 232-118-5 \| CAS no: 7787-49-7 Beryllium, bis(carbonato(2-))dihydroxytri- EC / List no: - \| CAS no: 66104-24-3 Beryllium dibromide EC / List no: 232-115-9 \| CAS no: 7787-46-4 Aluminium alloy, Al,Be EC / List no: 603-236-8 \| CAS no: 12770-50-2 Hexakis[μ-(acetato-O:O')]-μ4-oxotetraberyllium EC / List no: 242-785-4 \| CAS no: 19049-40-2 Zinc beryllium silicate EC / List no: - \| CAS no: 39413-47-3 Bis(pentane-2,4-dionato-O,O')beryllium EC / List no: 233-513-5 \| CAS no: 10210-64-7 Bertrandite (Be4(OH)2O(SiO3)2) EC / List no: 235-299-9 \| CAS no: 12161-82-9 Diethylberyllium EC / List no: 208-823-9 \| CAS no: 542-63-2 Beryllium oxyfluoride EC / List no: - \| CAS no: 63990-88-5 Beryllium phosphide (BeP2) EC / List no: - \| CAS no: 1268721-56-7 Beryllium diboride EC / List no: 235-443-0 \| CAS no: 12228-40-9 Beryllium hydrogen phosphate (1:1) EC / List no: - \| CAS no: 13598-15-7 Beryllium diiodide EC / List no: 232-119-0 \| CAS no: 7787-53-3 Beryllium hexaboride EC / List no: 235-657-4 \| CAS no: 12429-94-6 Silicic acid, beryllium salt EC / List no: 261-293-0 \| CAS no: 58500-38-2 Beryllium sulphate EC / List no: 236-842-2 \| CAS no: 13510-49-1 Beryllium di(acetate) EC / List no: 208-850-6 \| CAS no: 543-81-7 Beryllium diammonium tetrafluoride EC / List no: 238-948-4 \| CAS no: 14874-86-3 Beryllium telluride EC / List no: 235-451-4 \| CAS no: 12232-27-8 Beryllium orthosilicate EC / List no: 239-251-8 \| CAS no: 15191-85-2 Triberyllium nitride EC / List no: 215-132-6 \| CAS no: 1304-54-7	-	-	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
beryllium oxide	215-133-1	1304-56-9	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Bhanja	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
bifenazate (ISO); isopropyl 2-(4-methoxybiphenyl-3-yl)hydrazinecarboxylate	442-820-5	149877-41-8	STOT RE 2; Skin Sens. 1
bifenthrin (ISO); (2-methylbiphenyl-3-yl)methylrel-(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	617-373-6	82657-04-3	Carc. 2; Acute Tox. 3; Acute Tox. 2; STOT RE 1; Skin Sens. 1B
binapacryl (ISO); 2-sec-butyl-4,6-dinitrophenyl-3-methylcrotonate	207-612-9	485-31-4	Repr. 1B; Acute Tox. 4
biphenyl-2-ylamine	201-990-9	90-41-5	Carc. 2; Acute Tox. 4
biphenyl-3,3', 4,4'-tetrayltetraamine; diaminobenzidine	202-110-6	91-95-2	Carc. 1B; Muta. 2
biphenyl; diphenyl	202-163-5	92-52-4	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
bis(1,1-dimethyl-2-propynyloxy)dimethylsilane PLR-22; XC95-A0638	414-960-7	53863-99-3	Acute Tox. 4
bis(1,2,3-trithiacyclohexyldimethylammonium) oxalate; thiocyclam-oxalate	250-859-2	31895-22-4	Acute Tox. 4
bis(1-methylethyl)-dimethoxysilane EURENOR 5021; PSX 872	421-540-7	18230-61-0	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
bis(2,2,6,6-tetramethyl-4-piperidyl) succinate TINUVIN 780	402-940-0	62782-03-0	Eye Irrit. 2
bis(2,4,4-trimethylpentyl)dithiophosphonic acid	420-160-9	107667-02-7	Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
bis(2,4,6-trinitrophenyl)amine; hexyl	205-037-8	131-73-7	Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
bis(2,6-dimethoxybenzoyl)-2,4,4-trimethylpentylphosphinoxide CGI 403	412-010-6	145052-34-2	Skin Sens. 1
bis(2-chloroethyl) ether	203-870-1	111-44-4	Carc. 2; Acute Tox. 2; Acute Tox. 1
bis(2-dimethylaminoethyl)(methyl)amine	221-201-1	3030-47-5	Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
bis(2-ethylhexyl) dithiodiacetate DI(2-ETHYLHEXYL)DITHIODIGLYKOLAT; DP 327	404-510-8	62268-47-7	Acute Tox. 4; Skin Sens. 1
bis(2-ethylhexyl)-4,5-epoxycyclohexane-1,2-dicarboxylate	430-700-5	10138-36-0	Skin Sens. 1
bis(3,5-di-tert-butylsalicylato-O1,O2)zinc BONTRON E-84; E-84	403-360-0	42405-40-3	Flam. Sol. 1; Acute Tox. 4
bis(3-(trimethoxysilyl)propyl)amine	280-084-5	82985-35-1	Eye Dam. 1
bis(4-(1,2-bis(ethoxycarbonyl)ethylamino)-3-methylcyclohexyl)methane DESMOPHEN VP-LS 2973 E; DESMOPHEN VP-LS 2975 E; DESMOPHEN VP-LS 2985 E	412-060-9	136210-32-7	Skin Sens. 1
bis(4-dodecylphenyl)iodonium hexafluoroantimonate	404-420-9	71786-70-4	Skin Sens. 1
bis(4-fluorophenyl)-methyl-(1,2,4-triazol-4-ylmethyl)silane hydrochloride U 9649	401-380-4	89066-61-5	Eye Irrit. 2
bis(4-hydroxy-N-methylanilinium) sulphate	200-237-1	55-55-0	Acute Tox. 4; STOT RE 2; Skin Sens. 1
bis(4-methylbenzoyl)peroxide INTEROX-PMBP-70W; INTEROX-PMPB-70W	407-950-9	895-85-2	Org. Perox. B
bis(8-hydroxyquinolinium) sulphate	205-137-1	134-31-6	Acute Tox. 4
bis(chloromethyl) ether; oxybis(chloromethane)	208-832-8	542-88-1	Flam. Liq. 2; Carc. 1A; Acute Tox. 2; Acute Tox. 3; Acute Tox. 4
bis(d-gluconato-O1,O2)nickel	276-205-6	71957-07-8	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
bis(dimethyl-(2-hydroxyethyl)ammonium) 1,2-ethanediyl-bis(2-hexadecenylsuccinate) Z-27	421-660-1	-	Eye Dam. 1; Skin Sens. 1
bis(hydrogenated tallow C16-18-alkyl)hydroxylamine	418-370-0	143925-92-2	Skin Sens. 1
bis(hydroxylammonium) sulfate; hydroxylamine sulfate (2:1)	233-118-8	10039-54-0	Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
bis(N-(7-hydroxy-8-methyl-5-phenylphenazin-3-ylidene)dimethylammonium) sulfate SAFRANIN SHMN	406-770-8	149057-64-7	STOT RE 2; Eye Dam. 1; Skin Sens. 1
bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O')copper; bis(N-cyclohexyl-diazenium-dioxy)-copper; [Cu-HDO]	239-703-4	15627-09-5	Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O')copper; bis(N-cyclohexyl-diazenium-dioxy)-copper; [Cu-HDO]	608-595-4	312600-89-8	Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
bis(N-methyl-N-phenylhydrazine)sulfate GR101655A	423-170-1	618-26-8	Flam. Liq. 2; STOT RE 1; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
bis(piperidinothiocarbonyl) disulphide	202-328-1	94-37-1	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
bis(α,α-dimethylbenzyl) peroxide	201-279-3	80-43-3	Org. Perox. F; Repr. 1B; Skin Irrit. 2; Eye Irrit. 2
bis(η5-cyclopentadienyl)-bis(2,6-difluoro-3-[pyrrol-1-yl]-phenyl)titanium CGI 784	412-000-1	125051-32-3	Flam. Sol. 1; Repr. 2; STOT RE 2
bis-(6-hydroxy-4-methyl-5-(3-methylimidazolium-1-yl)-3-(4-phenylazo)-1H-pyridin-2-one)ethylene dilactate	421-560-6	-	STOT RE 2; Eye Dam. 1
bis-[4-(2,3-epoxipropoxi)phenyl]propane	216-823-5	1675-54-3	Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
bis[(1-methylimidazol)-(2-ethyl-hexanoate)], zinc complex TK 10891; XB 4458; XW 528; ZK XB 4458	405-635-0	-	Skin Irrit. 2; Eye Dam. 1
bis[4-(ethenyloxy)butyl] 1,3-benzenedicarboxylate VECTOMER E2200	413-930-0	130066-57-8	Skin Sens. 1
bis[[2,2',2''-nitrilotris-[ethanolato]]-1-N,O]-bis[2-(2-methoxyethoxy)ethoxy]-titanium TITANCHELAT ETAM	410-500-4	357921-97-2	Eye Dam. 1
bis[tributyl 4-(methylbenzyl)ammonium] 1,5-naphthalenedisulfonate MCP-304	415-210-1	160236-81-7	Acute Tox. 4; Eye Dam. 1
BK and JC viruses	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Blastomyces dermatitidis	-	-		F Fungi
bordeaux mixture; reaction products of copper sulphate with calcium dihydroxide	616-932-1	8011-63-0	Acute Tox. 4; Eye Dam. 1
Bordetella bronchiseptica	-	-		B Bacteria and similar species
Bordetella parapertussis	-	-		B Bacteria and similar species
Bordetella pertussis	-	-		B Bacteria and similar species
boron tribromide	233-657-9	10294-33-4	Acute Tox. 2; Skin Corr. 1A
boron trichloride	233-658-4	10294-34-5	Press. Gas; Acute Tox. 2; Skin Corr. 1B
boron trifluoride	231-569-5	7637-07-2	Press. Gas; Acute Tox. 2; Skin Corr. 1A
Borrelia burgdorferi	-	-		B Bacteria and similar species
Borrelia duttonii	-	-		B Bacteria and similar species
Borrelia recurrentis	-	-		B Bacteria and similar species
Borrelia spp.	-	-		B Bacteria and similar species
Bovine spongiform encephalopathy (BSE) and other related animal TSEs	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
bromadiolone (ISO); 3-[3-(4'-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one	249-205-9	28772-56-7	Repr. 1B; Acute Tox. 1; STOT RE 1
bromelain, juice	232-572-4	9001-00-7	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
bromine	231-778-1	7726-95-6	Acute Tox. 2; Skin Corr. 1A
bromoacetic acid	201-175-8	79-08-3	Acute Tox. 3; Skin Corr. 1A; Skin Sens. 1
bromobenzene	203-623-8	108-86-1	Flam. Liq. 3; Skin Irrit. 2
bromobenzylbromotoluene, reaction mass of isomers DBBT	402-210-1	99688-47-8	STOT RE 2; Skin Sens. 1
bromoethane; ethyl bromide	200-825-8	74-96-4	Flam. Liq. 2; Carc. 2; Acute Tox. 4
bromoethylene	209-800-6	593-60-2	Press. Gas; Flam. Gas 1; Carc. 1B
bromofenoxim (ISO); 3,5-dibromo-4-hydroxybenzaldehyde-O-(2,4-dinitrophenyl)-oxime	236-129-6	13181-17-4	Acute Tox. 4
bromoform; tribromomethane	200-854-6	75-25-2	Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
bromomethane; methylbromide	200-813-2	74-83-9	Press. Gas; Muta. 2; Acute Tox. 3; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
bromophos (ISO); O-4-bromo-2,5-dichlorophenyl O,O-dimethyl phosphorothioate	218-277-3	2104-96-3	Acute Tox. 4
bromophos-ethyl (ISO); O-4-bromo-2,5-dichlorophenyl; O,O-diethyl phosphorothioate	225-399-0	4824-78-6	Acute Tox. 3; Acute Tox. 4
bromoxynil (ISO) 3,5-dibromo-4-hydroxybenzonitrile; bromoxynil phenol show/hide 2,6-dibromo-4-cyanophenyl octanoate EC / List no: 216-885-3 \| CAS no: 1689-99-2 2,6-dibromo-4-cyanophenyl butyrate EC / List no: 223-374-9 \| CAS no: 3861-41-4 2,6-dibromo-4-cyanophenyl heptanoate EC / List no: 260-300-4 \| CAS no: 56634-95-8 3,5-dibromo-4-hydroxybenzonitrile EC / List no: 216-882-7 \| CAS no: 1689-84-5	216-882-7	1689-84-5	Repr. 2; Acute Tox. 2; Acute Tox. 3; Skin Sens. 1
bromoxynil heptanoate (ISO); 2,6-dibromo-4-cyanophenyl heptanoate	260-300-4	56634-95-8	Repr. 2; Acute Tox. 4; Skin Sens. 1
bromoxynil octanoate (ISO); 2,6-dibromo-4-cyanophenyl octanoate	216-885-3	1689-99-2	Repr. 2; Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
bronopol (INN); 2-bromo-2-nitropropane-1,3-diol	200-143-0	52-51-7	Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
Brucella abortus	-	-		B Bacteria and similar species
Brucella canis	-	-		B Bacteria and similar species
Brucella melitensis	-	-		B Bacteria and similar species
Brucella suis	-	-		B Bacteria and similar species
brucine nitrate	227-317-9	5786-97-0	Acute Tox. 2
brucine sulphate	225-432-9	4845-99-2	Acute Tox. 2
brucine; 2,3-dimethoxystrychnine	206-614-7	357-57-3	Acute Tox. 2
Brugia malayi	-	-		P Parasites
Brugia pahangi	-	-		P Parasites
bufa-4,20,22-trienolide, 6-(acetyloxy)-3-(β-D-glucopyranosyloxy)-8,14-dihydroxy-, (3β, 6β)-; red squill; scilliroside	208-077-4	507-60-8	Acute Tox. 2
bufencarb (ISO); reaction mass of 3-(1-methylbutyl)phenyl N-methylcarbamate and 3-(1-ethylpropyl)phenyl N-methylcarbamate	620-359-2	8065-36-9	Acute Tox. 3
Buffalopox virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.

Prikazano 1.601 - 1.700 od 4.821 rezultata.

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EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

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Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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