EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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Prikaz 2.901 - 3.000 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
hydrogen sodium N-carboxylatoethyl-N-octadec-9-enylmaleamate 2-BUTANEDIOIC ACID, MONOAMIDE WITH N-(9-OCTADECENYL)-3-AMINO	402-970-4	148292-42-6	Skin Sens. 1
hydrogen sulphide	231-977-3	7783-06-4	Flam. Gas 1; Press. Gas; Acute Tox. 2
hydroxo(2-(benzenesulfonamido)benzoato)zinc(II) SICORIN E 10197	403-750-0	113036-91-2	Acute Tox. 4
hydroxydisulfito platinum(II)acid	423-310-1	61420-92-6	Acute Tox. 4; STOT RE 2; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1
hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI); reaction mass of 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde and 3-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde	641-410-5	130066-44-3	Skin Sens. 1A
hydroxylamine ... % [> 55 % in aqueous solution];hydroxylamine ...% [≤ 55 % in aqueous solution]	232-259-2	7803-49-8	Unst. Expl.; Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
hydroxylamine ... % [> 55 % in aqueous solution];hydroxylamine ...% [≤ 55 % in aqueous solution]	232-259-2	7803-49-8	Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
hydroxylamine 4-methylben; zenesulfonate	258-872-5	53933-48-5	Expl. 1.1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxylamine dihydrogenphos; phate	242-818-2	19098-16-9	Expl. 1.1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxylamine phosphate	244-077-0	20845-01-6	Expl. 1.1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxylammonium chloride; hydroxylamine hydrochloride	226-798-2	5470-11-1	Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxylammonium hydrogensulfate; hydroxylamine sulfate(1:1)	233-154-4	10046-00-1	Expl. 1.1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxylammonium nitrate	236-691-2	13465-08-2	Expl. 1.1; Carc. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
hydroxyphosphonoacetic acid DP-3337	405-710-8	23783-26-8	Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
Hymenolepis diminuta	-	-		P Parasites
Hymenolepis nana	-	-		P Parasites
hymexazol (ISO);3-hydroxy-5-methylisoxazole	233-000-6	10004-44-1	Repr. 2; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
hyoscine	200-090-3	51-34-3	Acute Tox. 2; Acute Tox. 1
hyoscyamine	202-933-0	101-31-5	Acute Tox. 2
Hypr	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
imazalil (ISO); 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole	252-615-0	35554-44-0	Carc. 2; Acute Tox. 3; Acute Tox. 4; Eye Dam. 1
imazalil sulphate (ISO) powder; 1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imid azolium hydrogen sulphate;imazalil sulphate (ISO), aqueous solution; 1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imidazolium hydrogen sulphate	261-351-5	58594-72-2	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
imazalil sulphate (ISO) powder; 1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imid azolium hydrogen sulphate;imazalil sulphate (ISO), aqueous solution; 1-[2-(allyloxy)ethyl-2-(2,4- dichlorophenyl)]-1H-imidazolium hydrogen sulphate	261-351-5	58594-72-2	Acute Tox. 4; Skin Sens. 1
imazamox (ISO); (RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid	601-305-7	114311-32-9	Repr. 2
imazapyr (ISO);2-[4,5-dihydro-4-methyl-4-(1- methylethyl)-5-oxo-1H- imidazol-2-yl]-3-pyridine carboxylate	617-219-8	81334-34-1	Eye Irrit. 2
imidacloprid (ISO); (E)-1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine; (2E)-1-[(6-chloropyridin-3-yl) methyl]-N-nitroimidazolidin-2-imine	428-040-8	138261-41-3	Acute Tox. 3
imidazo[1,2-b]pyridazin hydrochloride	431-510-5	18087-70-2	Acute Tox. 4; Eye Irrit. 2
imidazole	206-019-2	288-32-4	Repr. 1B; Acute Tox. 4; Skin Corr. 1C
imiprothrin (ISO); reaction mass of: [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-cis-chrysanthemate; [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-trans-chrysanthemate	428-790-6	72963-72-5	Carc. 2; Acute Tox. 4; STOT SE 2
indium phosphide	244-959-5	22398-80-7	Carc. 1B; Repr. 2; STOT RE 1
indoxacarb (ISO); methyl (4aS)-7-chloro-2-{(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]carbamoyl}-2,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate	605-683-4	173584-44-6	Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Sens. 1B
Influenza viruses types A, B and C	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Inorganic compounds of mercury with the exception of mercuric sulphide and those specified elsewhere in this Annex	-	-	Acute Tox. 2; Acute Tox. 1; STOT RE 2
iodine	231-442-4	7553-56-2	Acute Tox. 4
iodoacetic acid	200-590-1	64-69-7	Acute Tox. 3; Skin Corr. 1A
iodoxybenzene	-	696-33-3	Expl.
ioxynil (ISO) 4-hydroxy-3,5-diiodobenzonitrile	216-881-1	1689-83-4	Repr. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Eye Irrit. 2
ioxynil octanoate (ISO); 4-cyano-2,6-diiodophenyl octanoate	223-375-4	3861-47-0	Repr. 2; Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	-	115937-89-8	Repr. 1B; Acute Tox. 4; STOT RE 2
ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	-	115850-69-6	Repr. 1B; Acute Tox. 4; STOT RE 2
ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	603-038-1	125225-28-7	Repr. 1B; Acute Tox. 4; STOT RE 2
iprobenfos(ISO); S-benzyl diisopropyl phosphorothioate	247-449-0	26087-47-8	Acute Tox. 4
iprodione (ISO); 3-(3,5-dichlorophenyl)-2,4-dioxo-N-isopropylimidazolidine-1-carboxamide	253-178-9	36734-19-7	Carc. 2
iprovalicarb (ISO); isopropyl [(2S)-3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl]carbamate	604-209-3	140923-17-7	Carc. 2
IPSP; S-ethylsulphinylmethyl O,O-diisopropylphosphorodithioate	-	5827-05-4	Acute Tox. 1; Acute Tox. 3
iron (II) sulfate	231-753-5	7720-78-7	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
iron (II) sulfate (1:1) heptahydrate; sulfuric acid, iron(II) salt (1:1), heptahydrate; ferrous sulfate heptahydrate	616-510-7	7782-63-0	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Iron (III) tris(4-methylbenzenesulfonate) JOF 2822 5F; JOF 2822 5FL; JOF 4443	420-960-8	77214-82-5	Eye Dam. 1
isazofos (ISO); O-(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O, O-diethyl phosphorothioate	255-863-8	42509-80-8	Acute Tox. 2; Acute Tox. 3; STOT RE 2; Skin Sens. 1
iso-butyl propionate	208-746-0	540-42-1	Flam. Liq. 3
isobenzan (ISO); 1,3,4,5,6,7,8,8-octachloro-1,3,3a,4,7,7a-hexahydro-4,7-methanoisobenzofuran	206-045-4	297-78-9	Acute Tox. 1; Acute Tox. 2
isobutane;isobutane (containing ≥ 0,1 % butadiene (203-450-8))	200-857-2	75-28-5	Flam. Gas 1; Press. Gas; Carc. 1A; Muta. 1B
isobutane;isobutane (containing ≥ 0,1 % butadiene (203-450-8))	200-857-2	75-28-5	Flam. Gas 1; Press. Gas
isobutyl 2-(4-(4-chlorophenoxy)phenoxy)propionate; clofop-isobutyl (ISO)	-	51337-71-4	Acute Tox. 4
isobutyl 3,4-epoxybutyrate IVAX	401-920-9	100181-71-3	Skin Irrit. 2; Skin Sens. 1
isobutyl acetate	203-745-1	110-19-0	Flam. Liq. 2
isobutyl acrylate	203-417-8	106-63-8	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
isobutyl but-3-enoate ISOBUTYLVINYL ACETATE; IVA	401-170-2	24342-03-8	Flam. Liq. 3
isobutyl formate	208-818-1	542-55-2	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
isobutyl methacrylate	202-613-0	97-86-9	Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Skin Sens. 1B
isobutyl nitrite	208-819-7	542-56-3	Flam. Liq. 2; Carc. 1B; Muta. 2; Acute Tox. 4
isobutylidene-(2-(2-isopropyl-4,4-dimethyloxazolidine-3-yl)-1,1-dimethylethyl)amine ZOLDINE RD-4	419-850-2	148348-13-4	Skin Corr. 1B
isobutylisopropyldimethoxysilane ALKYLSILANE TZ 01748; DYNASYLAN 9405; EURENOR(R) 5020; PSX 5305	402-580-4	111439-76-0	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
isobutyric acid	201-195-7	79-31-2	Acute Tox. 4
isobutyryl chloride	201-194-1	79-30-1	Flam. Liq. 2; Skin Corr. 1A
isodrin; (1α,4α,4aβ, 5β,8β,8aβ)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene	207-366-2	465-73-6	Acute Tox. 2; Acute Tox. 1
isoeugenol	202-590-7	97-54-1	Skin Sens. 1A
isofenphos (ISO); O-ethyl O-2-isopropoxycarbonylphenyl-isopropylphosphoramidothioate	246-814-1	25311-71-1	Acute Tox. 3
isoheptane	250-610-8	31394-54-4	Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
isooctane	247-861-0	26635-64-3	Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
isooctyl acrylate	249-707-8	29590-42-9	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
isopentane; 2-methylbutane	201-142-8	78-78-4	Flam. Liq. 1; Asp. Tox. 1; STOT SE 3
isopentyl acetate	204-662-3	123-92-2	Flam. Liq. 3
isopentyl formate	203-769-2	110-45-2	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
isopentyl propionate	203-322-1	105-68-0	Flam. Liq. 3
isoprene (stabilised); 2-methyl-1,3-butadiene	201-143-3	78-79-5	Flam. Liq. 1; Carc. 1B; Muta. 2
isoprocarb (ISO); 2-isopropylphenyl N-methylcarbamate	220-114-6	2631-40-5	Acute Tox. 4
isopropyl acetate	203-561-1	108-21-4	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
isopropyl chloroacetate	203-301-7	105-48-6	Flam. Liq. 3; Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
isopropyl formate	210-901-2	625-55-8	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
isopropyl propionate	211-300-8	637-78-5	Flam. Liq. 2
isopropylammonium 2-(3-benzoylphenyl)propionate	417-970-1	1379932-74-7	Acute Tox. 3; Acute Tox. 4; STOT RE 1; Eye Dam. 1
isoproturon (ISO); 3-(4-isopropylphenyl)-1,1-dimethylurea	251-835-4	34123-59-6	Carc. 2; STOT RE 2
isostearic acid monoisopropanolamide	431-540-9	170573-32-7	Skin Irrit. 2
isothioate (ISO); S-2-isopropylthioethyl O,O-dimethyl phosphorodithioate	-	36614-38-7	Acute Tox. 3
isoxaflutole (ISO); 5-cyclopropyl-1,2-oxazol-4-yl α,α,α-trifluoro-2-mesyl-p-tolyl ketone	604-222-4	141112-29-0	Repr. 2
isoxathion (ISO); O,O-diethyl O-5-phenylisoxazol-3-ylphosphorothioate	242-624-8	18854-01-8	Acute Tox. 3
Japanese B encephalitis	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Junin virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
kelevan (ISO); ethyl 5-(perchloro-5-hydroxypentacyclo[5,3,0,02,6,03,9,04,8]decan-5-yl)-4-oxopentanoate; ethyl 5-(1,2,3,5,6,7,8,9,10,10-decachloro-4-hydroxypentacyclo(5,2,1,02,6,03,9,05,8)dec-4-yl)-4-oxovalerate	620-410-9	4234-79-1	Acute Tox. 3; Acute Tox. 4
Kerosine (petroleum), hydrodesulfurized thermal cracked; Cracked kerosine [ complex combination of hydrocarbons obtained by fractionation from hydrodesulfurized thermal cracker distillate. It consists predomi nantly of hydrocarbons predominantly in the range of C8 to C16 and boiling in the range of approximately 120°C to 283°C (284°F to 541°F).] A complex combination of hydrocarbons obtained by fractionation from hydrodesulfurized thermal cracker distillate. It consists predominantly of hydrocarbons predominantly in the range of C8 to C16 and boiling in the range of approximately 120°C to 283°C (284°F to 541°F).	285-507-7	85116-55-8	Asp. Tox. 1
Kerosine (petroleum), hydrodesulfurized; Kerosine — unspecified [ complex combination of hydrocarbons obtained from a petroleum stock by treating with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 150 °C to 290 °C (302 °F to 554 °F).] A complex combination of hydrocarbons obtained from a petroleum stock by treating with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 150°C to 290°C (302°F to 554°F).	265-184-9	64742-81-0	Asp. Tox. 1
Kerosine (petroleum), hydrotreated; Kerosine — unspecified [ complex combination of hydrocarbons obtained from the distillation of petroleum and subsequent hydrotreatment. It consists predominantly of alkanes, cycloalkanes and alkylbenzenes having carbon numbers predominantly in the range of C12 through C16 and boiling in the range of approximately 230 °C to 270 °C (446 °F to 518 °F).] A complex combination of hydrocarbons obtained from the distillation of petroleum and subsequent hydrotreatment. It consists predominantly of alkanes, cycloalkanes and alkylbenzenes having carbon numbers predominantly in the range of C12 through C16 and boiling in the range of approximately 230°C to 270°C (446°F to 518°F).	309-944-0	101631-19-0	Asp. Tox. 1
Kerosine (petroleum), solvent-refined hydrodesulfurized; Kerosine — unspecified	307-033-2	97488-94-3	Asp. Tox. 1
Kerosine (petroleum), solvent-refined sweetened; Kerosine — unspecified [ complex combination of hydrocarbons obtained from a petroleum stock by solvent refining and sweetening and boiling in the range of approximately 150 °C to 260 °C (302 °F to 500 °F).] A complex combination of hydrocarbons obtained from a petroleum stock by solvent refining and sweetening and boiling in the range of approximately 150°C to 260°C (302°F to 500°F).	295-416-4	92045-36-8	Asp. Tox. 1
Kerosine (petroleum), straight-run wide-cut; Straight run kerosine [A complex combination of hydrocarbons obtained as a wide cut hydrocarbon fuel cut from atmospheric distillation and boiling in the range of approximately 70 °C to 220 °C (158 °F to 428 °F).] A complex combination of hydrocarbons obtained as a wide cut hydrocarbon fuel cut from atmospheric distillation and boiling in the range of approximately 70°C to 220°C (158°F to 428°F).	295-418-5	92045-37-9	Asp. Tox. 1
Kerosine (petroleum), sweetened; Kerosine — unspecified [ complex combination of hydrocarbons obtained by subjecting a petroleum distillate to a sweetening process to convert mercaptans or to remove acidic impurities. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of 130 °C to 290 °C (266 °F to 554 °F).] A complex combination of hydrocarbons obtained by subjecting a petroleum distillate to a sweetening process to convert mercaptans or to remove acidic impurities. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of 130°C to 290°C (266°F to 554°F).	294-799-5	91770-15-9	Asp. Tox. 1
Kerosine (petroleum); Straight run kerosine [A complex combination of hydrocarbons produced by the distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 150°C to 290°C (320°F to 554°F).] A complex combination of hydrocarbons produced by the distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 150°C to 290°C (320°F to 554°F).	232-366-4	8008-20-6	Asp. Tox. 1
ketoconazole; 1-[4-[4-[[(2SR, 4RS)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone	265-667-4	65277-42-1	Repr. 1B; Acute Tox. 3; STOT RE 2
Klebsiella oxytoca	-	-		B Bacteria and similar species

Prikaz 2.901 - 3.000 od 4.821 rezultata.

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EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

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Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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