EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 14 lipnja 2024. Database contains 4821 unique substances/entries.
Filter the list

680-302-2
95266-40-3
STOT RE 2; Skin Sens. 1B
236-771-7
13477-70-8
Carc. 1A; STOT RE 1; Skin Sens. 1
-
74646-29-0
Carc. 1A; STOT RE 1; Skin Sens. 1
233-844-5
10381-36-9
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
234-495-1
12007-02-2
Carc. 1A; STOT RE 1; Skin Sens. 1
234-829-6
12035-72-2
Carc. 1A; Muta. 2; Acute Tox. 3; STOT RE 1; Skin Sens. 1
-
12137-12-1
Carc. 1A; STOT RE 1; Skin Sens. 1
TZ 02508
413-320-4
869-59-0
STOT RE 1; Skin Irrit. 2
-
-
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
202-908-4
101-02-0
Eye Irrit. 2; Skin Irrit. 2
442-960-7
332350-93-3
Acute Tox. 3; Eye Dam. 1
-
-
Acute Tox. 3
TRYPROPYLAMMONIUM DIHYDROGENPHOSPHAT
433-700-3
35687-90-2
Acute Tox. 4
-
-
Acute Tox. 3
-
7276-58-6
Acute Tox. 4
ACETOACETYLORTHOSINIC ACID, A6-SALT
403-760-5
68030-79-5
Skin Sens. 1
PIGMENTBLAU 1755
403-210-4
108300-90-9
Eye Dam. 1
LEXMARK YELLOW DYE 415; PRISM YELLOW
406-073-9
131013-81-5
Acute Tox. 3
237-159-2
13674-87-8
Carc. 2
BROWN 1612969
407-110-1
480445-87-2
Eye Dam. 1; Skin Sens. 1
SÄUREBLAU 82 226
402-500-8
104105-46-6
Eye Dam. 1
SCARLET 12 04 262
406-820-9
159317-41-6
Eye Irrit. 2
BLUE TZ 4312
423-770-3
-
Eye Dam. 1
427-710-7
215612-56-9
Eye Dam. 1; Skin Sens. 1
429-240-8
212652-59-0
Eye Dam. 1
BLEU REACTIF CAC 10; DIOXAZINE MONCHLORTRIAZINE; FAT NO. 40 407; REACTIVE BLUE CAC 10
410-130-3
136248-03-8
Skin Sens. 1
430-280-3
844491-96-9
Skin Sens. 1
440-480-2
341026-59-3
Eye Dam. 1; Skin Sens. 1
C.I. REACTIVE YELLOW 174; GIALLO REATTIVO 174; JAUNE REACTIF 174; REAKTIV GELB 174
402-170-5
106359-91-5
Skin Sens. 1
423-100-1
-
Eye Dam. 1
TURQUOISE 10 40 518
411-430-7
-
Eye Dam. 1; Skin Sens. 1
SOLAMINLICHTBLAU VGRL 133
413-590-3
164058-22-4
Carc. 1B
ACID BLUE 349; AZO-METALCOMPLEX-BLUE AP 1149; BLEU ACIDE 349; C.I. ACID BLUE 349; SELLASET BLEU H; SELLASET BLUE H
402-870-0
93952-24-0
Eye Dam. 1
BI 3277; NOIR CORSE SANODAL H3LW CONC.; SANODAL DEEP BLACK H-3LW CONC.; SANODAL TIEFSCHWARZ H-3LW; SANODAL TIEFSCHWARZ H-3LW KONZ.
400-810-8
106084-79-1
Muta. 2
RED JB 747
418-220-4
-
Skin Sens. 1
237-410-6
13775-53-6
STOT RE 1; Acute Tox. 4
239-148-8
15096-52-3
STOT RE 1; Acute Tox. 4
TRILON(R) ES 9910
414-130-4
119710-96-2
Acute Tox. 4
TRILON(R) ES 9851
414-070-9
129050-62-0
Skin Corr. 1B
422-090-4
172737-80-3
Eye Dam. 1
225-768-6
5064-31-3
Carc. 2; Acute Tox. 4; Eye Irrit. 2
REACTIVE BLUE 245
407-580-8
130201-51-3
Eye Dam. 1
-
138182-18-0
Repr. 2; STOT RE 2
604-291-0
142469-14-5
Skin Sens. 1
215-244-5
1314-84-7
Water-react. 1; Acute Tox. 2
218-828-8
2244-21-5
Ox. Sol. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
220-767-7
2893-78-9
Ox. Sol. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
610-700-3
51580-86-0
Acute Tox. 4; Eye Irrit. 2; STOT SE 3
-
-
P Parasites
-
-
P Parasites
-
-
P Parasites
-
-
P Parasites
232-650-8
9002-07-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Any of the volatile predominately terpenic fractions or distillates resulting from the solvent extraction of, gum collection from, or pulping of softwoods. Composed primarily of the C10H16 terpene hydrocarbons: α-pinene, β-pinene, limonene, 3-carene, camphene. May contain other acyclic, monocyclic, or bicyclic terpenes, oxygenated terpenes, and anethole. Exact composition varies with refining methods and the age, location, and species of the softwood source.
232-350-7
8006-64-2
Flam. Liq. 3; Acute Tox. 4; Asp. Tox. 1; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
231-170-6
7440-61-1
Acute Tox. 2; STOT RE 2
show/hide
Uranium dioxide EC / List no: 215-700-3 | CAS no: 1344-57-6
Tetrakis(pentane-2,4-dionato-O,O')uranium EC / List no: 265-498-6 | CAS no: 65137-03-3
Uranium EC / List no: 231-170-6 | CAS no: 7440-61-1
Bis(formato-O)dioxouranium EC / List no: 241-063-6 | CAS no: 16984-59-1
Bis(2-ethylhexanoato-O)dioxouranium EC / List no: 267-849-9 | CAS no: 67939-77-9
Uranium disulphide EC / List no: 234-884-6 | CAS no: 12039-14-4
Nitric acid, uranium salt EC / List no: - | CAS no: 15905-86-9
Bis(nitrato-O,O')dioxouranium EC / List no: 253-053-9 | CAS no: 36478-76-9
Uranium tetraiodide EC / List no: 236-735-0 | CAS no: 13470-22-9
Tetraammonium uranyl tricarbonate, of uranium depleted in uranium-235 EC / List no: 241-988-5 | CAS no: 18077-77-5
Uranium trioxide EC / List no: 215-701-9 | CAS no: 1344-58-7
Uranium hydride (UH3) EC / List no: - | CAS no: 13598-56-6
Uranium carbide (UC2) EC / List no: - | CAS no: 12071-33-9
Hydrogen dioxo[phosphato(3-)-O,O']uranate(1-) EC / List no: 242-306-9 | CAS no: 18433-48-2
Triuranium tetraphosphide EC / List no: 234-871-5 | CAS no: 12037-84-2
Uranium hydride EC / List no: 257-346-2 | CAS no: 51680-55-8
Uranium trifluoride EC / List no: 237-404-3 | CAS no: 13775-06-9
Dioxobis(pentane-2,4-dionato-O,O')uranium EC / List no: 241-951-3 | CAS no: 18039-69-5
Uranium nitrate EC / List no: - | CAS no: 13826-82-9
Uranium diboride EC / List no: 234-508-0 | CAS no: 12007-36-2
Titanate(4-), oxobis[phosphato(3-)]-, barium (1:2), uranium-doped EC / List no: 309-550-9 | CAS no: 100403-10-9
Nitric acid, uranium(6+) salt EC / List no: - | CAS no: 20820-60-4
Barium uranium oxide EC / List no: - | CAS no: 10380-31-1
Magnesium uranium(4+) hexaacetate EC / List no: 243-905-8 | CAS no: 20596-93-4
Uranium fluoride (U2F9) EC / List no: - | CAS no: 12134-48-4
Calcines, uranium ore-conc.
Calcined precipitates of ammonium, magnesium or sodium uranates obtained from natural uranium ores.
EC / List no: 297-819-0 | CAS no: 93763-02-1
Nickel triuranium decaoxide EC / List no: 239-876-6 | CAS no: 15780-33-3
Zinc tetrakis(acetato-O)dioxouranate EC / List no: 251-762-8 | CAS no: 33959-50-1
Uranium disilicide EC / List no: 234-906-4 | CAS no: 12039-85-9
Uranium carbide (UC) EC / List no: - | CAS no: 12070-09-6
Zinc bis(acetato-O)dioxouranate EC / List no: 233-390-8 | CAS no: 10138-94-0
Uranium nitride EC / List no: - | CAS no: 12058-37-6
Nickel uranyl tetraacetate, of uranium depleted in uranium-235 EC / List no: 275-994-4 | CAS no: 71767-12-9
Oxobis(pentane-2,4-dionato-O,O')uranium EC / List no: 254-311-3 | CAS no: 39136-40-8
Dichlorodioxouranium EC / List no: 232-246-1 | CAS no: 7791-26-6
Uranium ditelluride EC / List no: 235-249-6 | CAS no: 12138-37-3
Triuranium octaoxide EC / List no: 215-702-4 | CAS no: 1344-59-8
Resin acids and Rosin acids, uranyl salts EC / List no: 273-325-0 | CAS no: 68956-97-8
Uranium hexafluoride EC / List no: 232-028-6 | CAS no: 7783-81-5
Disodium heptaoxodiuranate, of uranium depleted in uranium-235 EC / List no: 237-286-3 | CAS no: 13721-34-1
Uranium pentafluoride EC / List no: 237-405-9 | CAS no: 13775-07-0
Acetic acid, uranium(4+) zinc salt EC / List no: 243-904-2 | CAS no: 20596-91-2
Uranium triiodide EC / List no: 237-406-4 | CAS no: 13775-18-3
Difluorodioxouranium EC / List no: 236-898-8 | CAS no: 13536-84-0
Dipotassium heptaoxodiuranate EC / List no: 232-217-3 | CAS no: 7790-63-8
Magnesium diuranium heptaoxide EC / List no: 236-982-4 | CAS no: 13568-61-1
polysilicate EC / List no: - | CAS no: 12427-14-4
Uranyl acetate-2H2O EC / List no: 629-550-5 | CAS no: 6159-44-0
Uranium diselenide EC / List no: 235-245-4 | CAS no: 12138-21-5
Nasturan EC / List no: 690-098-7 | CAS no: 1317-99-3
Sodium uranyl triacetate, of uranium depleted in uranium-235 EC / List no: 241-714-4 | CAS no: 17712-38-8
Uranium dioxideperoxide EC / List no: 234-852-1 | CAS no: 12036-71-4
[oxalato(2-)-O,O']dioxouranium EC / List no: 217-986-5 | CAS no: 2031-89-2
Bis(nitrato-O)dioxouranium EC / List no: 233-266-3 | CAS no: 10102-06-4
Dioxo[sulphato(2-)-O]uranium EC / List no: 215-240-3 | CAS no: 1314-64-3
Disodium uranium tetraoxide EC / List no: 236-846-4 | CAS no: 13510-99-1
Dipotassium uranyl bis(sulphate), of uranium depleted in uranium-235 EC / List no: 262-284-4 | CAS no: 60542-74-7
Sodium tris(benzeneacetato-O)dioxouranate(1-) EC / List no: 309-040-6 | CAS no: 99800-13-2
Bis(acetato-O)dioxouranium EC / List no: 208-767-5 | CAS no: 541-09-3
Uranium tetrachloride EC / List no: 233-057-7 | CAS no: 10026-10-5
Calcium diuranium heptaoxide EC / List no: 237-428-4 | CAS no: 13780-21-7
Diammonium diuranium heptaoxide EC / List no: 231-986-2 | CAS no: 7783-22-4
Uranium tetraboride EC / List no: 234-520-6 | CAS no: 12007-84-0
Uranium tetrafluoride EC / List no: 233-170-1 | CAS no: 10049-14-6
Uranium tetrabromide EC / List no: 236-734-5 | CAS no: 13470-20-7
Lead uranate pigment EC / List no: 287-565-9 | CAS no: 85536-79-4
-
-
Acute Tox. 2; STOT RE 2
200-123-1
51-79-6
Carc. 1B
ITC 826 CONCENTRATE
422-720-8
166242-53-1
Carc. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
203-677-2
109-52-4
Skin Corr. 1B
D,L-VALINEAMIDE
402-840-7
20108-78-5
Repr. 2; Eye Irrit. 2; Skin Sens. 1
218-894-8
2275-23-2
Acute Tox. 3; Acute Tox. 4
424-390-0
93280-40-1
Acute Tox. 4; STOT RE 2; Eye Dam. 1
BTN; VPO CATALYST
406-260-5
58834-75-6
Eye Irrit. 2; Skin Sens. 1
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
217-681-7
1929-77-7
Acute Tox. 4
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
B Bacteria and similar species
-
-
B Bacteria and similar species
-
-
B Bacteria and similar species
256-599-6
50471-44-8
Carc. 2; Repr. 1B; Skin Sens. 1
203-545-4
108-05-4
Flam. Liq. 2; Carc. 2; Acute Tox. 4; STOT SE 3
200-831-0
75-01-4
Press. Gas; Flam. Gas 1; Carc. 1A
201-377-6
81-81-2
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.
295-549-8
92062-34-5
Carc. 1B
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
601-810-2
12185-10-3
Pyr. Sol. 1; Acute Tox. 2; Skin Corr. 1A
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
P Parasites
607-955-8
2655-14-3
Acute Tox. 4
215-535-7
1330-20-7
Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
215-089-3
1300-71-6
Acute Tox. 3; Skin Corr. 1B
215-091-4
1300-73-8
Acute Tox. 3; STOT RE 2
219-364-9
2425-10-7
Acute Tox. 4
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
-
-
B Bacteria and similar species
-
-
B Bacteria and similar species
-
-
B Bacteria and similar species
-
-
B Bacteria and similar species
Z-6
402-280-3
149144-82-1
Eye Irrit. 2; Skin Irrit. 2
205-232-8
136-23-2
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
238-270-9
14324-55-1
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
231-592-0
7646-85-7
Acute Tox. 4; Skin Corr. 1B
show/hide
Zinc chromate EC / List no: 236-878-9 | CAS no: 13530-65-9
C.I. Pigment Yellow 36 EC / List no: 609-398-6 | CAS no: 37300-23-5
Chromic acid, potassium zinc salt EC / List no: 255-252-6 | CAS no: 41189-36-0
Pentazinc chromate octahydroxide EC / List no: 256-418-0 | CAS no: 49663-84-5
Potassium hydroxyoctaoxodizincatedichromate(1-) EC / List no: 234-329-8 | CAS no: 11103-86-9
Zinc dichromate EC / List no: 237-843-0 | CAS no: 14018-95-2
-
-
Carc. 1A; Acute Tox. 4; Skin Sens. 1
425-240-7
-
Eye Dam. 1

Export search results to: