EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 11 rujna 2024. Database contains 4821 unique substances/entries.

Filter the list

Prikaz 1.501 - 1.600 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC
N-(2-(6-ethyl-7-(4-methylphenoxy)-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)propyl)-2-octadecyloxybenzamide UM-229	407-070-5	142859-67-4	Skin Sens. 1
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate; 4-(N-ethyl-N-2-methanesulphonylaminoethyl)-2-methylphenylenediamine sesquisulphate monohydrate	247-161-5	25646-71-3	Acute Tox. 4; Skin Sens. 1
N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide; (4-acetamido-2,2,6,6-tetra; methyl-1-piperidinyl)oxidanyl	423-840-3	14691-89-5	Acute Tox. 4
N-(2',6'-dimethylphenyl)-2-piperidinecarboxamide hydrochloride PPX-HCL	417-950-0	65797-42-4	Acute Tox. 4
N-(1,3-dimethylbutyl)-N'-(phenyl)-1,4-benzoquinonediimine	429-640-2	52870-46-9	Eye Irrit. 2
N,N-dimethylhydrazine	200-316-0	57-14-7	Flam. Liq. 2; Carc. 1B; Acute Tox. 3; Skin Corr. 1B
N,N-dimethylbenzene-1,3-diamine	220-623-3	2836-04-6	Acute Tox. 3
N,N-dimethylaniline	204-493-5	121-69-7	Carc. 2; Acute Tox. 3
N,N-dimethyl-p-toluidine	202-805-4	99-97-8	Acute Tox. 3; STOT RE 2
N,N-dimethyl-o-toluidine	210-199-8	609-72-3	Acute Tox. 3; STOT RE 2
N,N-dimethyl-m-toluidine	204-495-6	121-72-2	Acute Tox. 3; STOT RE 2
N,N-diethylaniline	202-088-8	91-66-7	Acute Tox. 3; STOT RE 2
N,N-diethyl-m-toluamide; deet	205-149-7	134-62-3	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
N,N-bis(cocoyl-2-oxypropyl)-N,N-dibutylammonium bromide	431-530-4	1380226-29-8	Skin Corr. 1A; Skin Sens. 1
N,N,N-trimethylanilinium chloride	205-319-0	138-24-9	Acute Tox. 3
N,N,N,N-tetrakis(4,6-bis(butyl- (N-methyl-2,2,6,6-tetramethyl piperidin-4-yl)amino)triazin-2- yl)-4,7-diazadecane-1,10- diamine CHIMASSORB 119; LOWILITE 19	401-990-0	106990-43-6	Skin Sens. 1
N,N,N',N'-tetraglycidyl-4,4'-diamino-3,3'-diethyldiphenylmethane PFMT 1848	410-060-3	130728-76-6	Muta. 2; Skin Sens. 1
N,N'—1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)-formamide LICHTSCHUTZMITTEL 1736	413-610-0	124172-53-8	Eye Irrit. 2
N,N'-methylenedimorpholine; N,N'-methylenebismorpholine [formaldehyde released from N,N'-methylenebismorpholine]; [MBM]	227-062-3	5625-90-1	Carc. 1B; Muta. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1; Eye Dam. 1
N,N'-dimethylbenzidine	-	2810-74-4	Acute Tox. 4
N,N'-dihexadecyl-N,N'-bis(2-hydroxyethyl)propanediamide QUESTAMIDE H	422-560-9	149591-38-8	Repr. 2; Eye Irrit. 2
N,N'-diacetylbenzidine	210-338-2	613-35-4	Carc. 1B; Muta. 2; Acute Tox. 4
N,N'-bis{6-chloro-4-[6-(4-vinylsulfonylphenylazo)-2,7-disulfonicacid-5-hydroxynapht-4-ylamino]-1,3,5-triazin-2-yl}-N-(2-hydroxyethyl)ethane-1,2-diamine, sodium salt RED REN 363	419-500-9	171599-85-2	Eye Dam. 1; Skin Sens. 1
N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide NYLOSTAB S-EED; NYSEED	419-710-0	42774-15-2	Acute Tox. 4; Eye Irrit. 2
N, N-hydrazinodiacetic acid F.H.D.A.	403-510-5	19247-05-3	Acute Tox. 3; STOT RE 2; Skin Sens. 1
N, N-dimethylanilinium tetrakis(pentafluorophenyl)borate B1; N,N-DIMETHYLANILINUM TETRAKIS(PENTAFLUOROPHENYL)BORATE; TÉTRAKIS(PENTAFLUOROPHÉNYL)BORATE DE N,N-DIMÉTHYLANILINIUM	422-050-6	118612-00-3	Carc. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
N, N-dimethyl-2-(3-(4-chloro phenyl)-4,5-dihydropyrazol-1- ylphenylsulphonyl)ethylamine HOSTALUX VP 3481	401-410-6	10357-99-0	STOT RE 2; Skin Sens. 1
N, N-diethyl-N',N'-dimethylpropan-1,3-diyl-diamine DDPD	406-610-7	62478-82-4	Flam. Liq. 3; Acute Tox. 4; STOT RE 2; Skin Corr. 1A
N, N-dibutyl-(2,5-dihydro-5-thioxo-1H-tetrazol-1-yl)acetamide	418-290-6	168612-06-4	Eye Irrit. 2; Skin Sens. 1
N, N-bis(trimethylsilyl)aminopropylmethyldiethoxysilane	445-890-5	201290-01-9	Acute Tox. 4; Skin Sens. 1
N, N-bis(3-aminopropyl)methylamine	203-336-8	105-83-9	Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
N, N-bis(2-ethylhexyl)-((1,2,4- triazol-1-yl)methyl)amine CM 23-376; REOMET 30	401-280-0	91273-04-0	Skin Corr. 1B; Skin Sens. 1
N, N-bis(2-(p-toluenesulfonyloxy)ethyl)-p-toluenesulfonamide DIETHANOLAMIN-TRITOSYLAT	412-920-3	16695-22-0	Skin Sens. 1
N, N-(dimethylamino)thioacetamide hydrochloride	435-470-1	27366-72-9	Repr. 1B
N, N,N',N'-tetramethylethylenediamine	203-744-6	110-18-9	Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1B
N, N,N',N'-tetramethyldithiobis(ethylene)diamine dihydrochloride AF-172; FPC 114	405-300-9	17339-60-5	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
N, N,N',N'-tetramethyl-p-phenylenediamine	202-831-6	100-22-1	Acute Tox. 4
N, N,N',N'-tetramethyl-3,3'-(propylenebis(iminocarbonyl-4,1-phenylenazo(1,6-dihydro-2-hydroxy-4-methyl-6-oxopyridine-3,1-diyl)))di(propylammonium) dilactate CARTASOL BRILLIANT YELLOW K-6G; CARTASOL BRILLIANT YELLOW K-6G CONC.; GIALLO BRILLANTE CARTASOL K-6G CONC.; JAUNE BRILLANT CARTASOL K-RWA 3904; RWA 3904	403-340-1	164578-09-0	Eye Dam. 1
N, N'-ethylenebis(vinylsulfonylacetamide) H-603	404-790-1	66710-66-5	Eye Dam. 1; Skin Sens. 1
N, N'-diphenyl-p-phenylenediamine; N, N'-diphenyl-1,4-benzenediamine	200-806-4	74-31-7	Skin Sens. 1
N, N'-bis(trifluoroacetyl)-S, S'-bis-L-homocysteine BMS 208143-01; BTHC	429-670-6	105996-54-1	Eye Dam. 1; Skin Sens. 1
N, N'-(2,2-dimethylpropylidene)hexamethylenediamine LUPRAGEN VP 9159	401-660-6	1000-78-8	Skin Irrit. 2; Skin Sens. 1
N, N',N''-tris(2-methyl-2,3-epoxypropyl)-perhydro-2,4,6-oxo-1,3,5-triazine	435-010-8	26157-73-3	Muta. 2
N, N''-(methylenedi-4,1-phenylene)bis[N'-octyl]urea	445-760-8	-	Eye Dam. 1; Resp. Sens. 1
N, N''-(methylenedi-4,1-phenylene)bis[N'-(4-methylphenyl)urea]	429-380-1	133336-92-2	Skin Sens. 1
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide	435-860-1	214417-91-1	Skin Sens. 1
Mycoplasma pneumoniae	-	-		B Bacteria and similar species
Mycoplasma hominis	-	-		B Bacteria and similar species
Mycoplasma caviae	-	-		B Bacteria and similar species
Mycobacterium xenopi	-	-		B Bacteria and similar species
Mycobacterium ulcerans	-	-		B Bacteria and similar species
Mycobacterium tuberculosis	-	-		B Bacteria and similar species
Mycobacterium szulgai	-	-		B Bacteria and similar species
Mycobacterium simiae	-	-		B Bacteria and similar species
Mycobacterium scrofulaceum	-	-		B Bacteria and similar species
Mycobacterium paratuberculosis	-	-		B Bacteria and similar species
Mycobacterium microti	-	-		B Bacteria and similar species
Mycobacterium marinum	-	-		B Bacteria and similar species
Mycobacterium malmoense	-	-		B Bacteria and similar species
Mycobacterium leprae	-	-		B Bacteria and similar species
Mycobacterium kansasii	-	-		B Bacteria and similar species
Mycobacterium fortuitum	-	-		B Bacteria and similar species
Mycobacterium chelonae	-	-		B Bacteria and similar species
Mycobacterium bovis (except BCG strain)	-	-		B Bacteria and similar species
Mycobacterium avium/intracellulare	-	-		B Bacteria and similar species
Mycobacterium africanum	-	-		B Bacteria and similar species
myclobutanil(ISO);2-(4-chlorophenyl)-2-(1H-1,2,4- triazol-1-ylmethyl)hexanenitrile SYSTHANE TECHNICAL	410-400-0	88671-89-0	Repr. 2; Acute Tox. 4; Eye Irrit. 2
musk ketone; 3,5-dinitro-2,6-dimethyl-4-tert-butylacetophenone; 4'-tert-butyl-2', 6'-dimethyl-3',; 5'-dinitroacetophenone	201-328-9	81-14-1	Carc. 2
muscalure; cis-tricos-9-ene	248-505-7	27519-02-4	Skin Sens. 1B
Mumps virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Mucambo virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
morphothion (ISO); O, O-dimethyl-S-(morpholinocarbonylmethyl) phosphorodithioate	205-628-0	144-41-2	Acute Tox. 3
morpholine-4-carbonyl chloride	239-213-0	15159-40-7	Carc. 2; Eye Irrit. 2; Skin Irrit. 2
morpholine	203-815-1	110-91-8	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
Morganella morganii	-	-		B Bacteria and similar species
morfamquat sulfate	-	29873-36-7	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
morfamquat dichloride	225-062-8	4636-83-3	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
morfamquat (ISO); 1,1'-bis(3,5-dimethylmorpholinocarbonylmethyl)-4,4'-bipyridilium ion	-	7411-47-4	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Mopeia virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
monuron (ISO); 3-(4-chlorophenyl)-1,1-dimethylurea	205-766-1	150-68-5	Carc. 2; Acute Tox. 4
monosodium 3-cyano-5-fluoro-6-hydroxypyridine-2-olate	429-570-2	213990-58-0	Skin Sens. 1
monolinuron (ISO); 3-(4-chlorophenyl)-1-methoxy-1-methylurea	217-129-5	1746-81-2	Acute Tox. 4; STOT RE 2
monocrotophos (ISO); dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate	230-042-7	6923-22-4	Muta. 2; Acute Tox. 2; Acute Tox. 3
monobenzone; 4-hydroxyphenyl benzyl ether; hydroquinone monobenzyl ether	203-083-3	103-16-2	Eye Irrit. 2; Skin Sens. 1
monoalkylor monoaryl or monoalkylaryl esters of acrylic acid with the exception of those specified elsewhere in this Annex	-	-	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
monoalkyl or monoaryl or monoalkyaryl esters of methacrylic acid with the exception of those specified elsewhere in this Annex	-	-	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
mono[2-(dimethylamino)ethyl]monohydrogen-2-(hexadec-2-enyl)butanedioate and/or mono[2-(dimethylamino)ethyl]monohydrogen-3-(hexadec-2-enyl)butanedioate Z-22	415-880-5	779343-34-9	Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
mono-methylamine;mono-methylamine ... %	200-820-0	74-89-5	Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
mono-methylamine;mono-methylamine ... %	200-820-0	74-89-5	Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
mono-2-[2-(4-dibenzo[b, f][1,4]thiazepin-11-yl)piperazinium-1-yl]ethoxy)ethanol trans-butenedioate ICI204636 HYDROGEN FUMARATE	415-180-1	773058-82-5	Acute Tox. 4; Eye Dam. 1
Monkeypox virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
molybdenum trioxide	215-204-7	1313-27-5	Carc. 2; Eye Irrit. 2; STOT SE 3
molybdenum nickel tetraoxide	238-034-5	14177-55-0	Carc. 1A; STOT RE 1; Skin Sens. 1
molybdenum nickel oxide	-	12673-58-4	Carc. 1A; STOT RE 1; Skin Sens. 1
molybdenum nickel hydroxide oxide phosphate	268-585-7	68130-36-9	Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
molinate (ISO);S-ethyl 1-perhydroazepinecarbothioate; S-ethyl perhydroazepine-1-carbothioate	218-661-0	2212-67-1	Carc. 2; Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1
mixed linear and branched C14-15 alcohols ethoxylated, reaction product with epichlorohydrin NUPORE G45-10	420-480-9	158570-99-1	Skin Irrit. 2; Skin Sens. 1
mix-cresol	215-293-2	1319-77-3	Acute Tox. 3; Skin Corr. 1B
mipafox (ISO); N,N'-di-isopropylphosphorodiamidic fluoride	206-742-3	371-86-8	STOT SE 1
Mineral wool, with the exception of those specified elsewhere in this Annex [Man-made vitreous (silicate) fibres with random orientation with alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content greater than 18 % by weight] [Man-made vitreous (silicate) fibres with random orientation with alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content greater than 18 % by weight] show/hide Glass, oxide, chemicals This category encompasses the various chemical substances manufactured in the production of inorganic glasses. For purposes of this category, 'glass' is defined as an amorfous, inorganic, transparent, translucent or opaque material traditionally formed by fusion of sources of silica with a flux, such as an alkali-metal carbonate, boron oxide, etc. and a stabilizer, into a mass which is cooled to a rigid condition without crystallization in the case of transparent or liquid-phase separated glass or with controlled crystallization in the case of glass-ceramics. The category consists of the various chemical substances, other than by-products or impurities, which are formed during the production of various glasses and concurrently incorporated into a glass mixture. All glasses contain one or more of these substances, but few, if any, contain all of them. The elements listed below are principally present as components of oxide systems but some may also be present as halides or chalcogenides, in multiple oxidation states, or in more complex compounds. Trace amounts of other oxides or chemical compounds may be present. Oxides of the first seven elements listed* comprise more than 95 percent, by weight, of the glass produced. @Aluminium@Lead@Boron@Lithium@Calcium@Manganese@Magnesium@Molybdenum@Potassium@Neodymium@Silicon@Nickel@Sodium*@Niobium@Antimony@Nitrogen@Arsenic@Phosphorus@Barium@Praseodymium@Bismuth@Rubidium@Cadmium@Selenium@Carbon@Silver@Cerium@Strontium@Cesium@Sulfur@Chromium@Tellurium@Cobalt@Tin@Copper@Titanium@Germanium@Tungsten@Gold@Uranium@Holmium@Vanadium@Iron@Zinc@Lanthanum@Zirconium EC / List no: 266-046-0 \| CAS no: 65997-17-3 Glass Wool EC / List no: - \| CAS no: 308066-92-4	-	-	Carc. 2

Prikaz 1.501 - 1.600 od 4.821 rezultata.

Export search results to:

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

RELEVANT LEGISLATION

Contact EUCLEF Helpdesk

Contact Helpdesk

Last updated 11 rujna 2024. Database contains 4821 unique substances/entries.

Footer Nav Items