EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU REACH: List of SVHC
Di-, tri- and tetrachlorotetradecane	950-299-5	-		yes
Nonylphenol, ethoxylated (EO = 10)	939-993-9	-		yes
Reaction products of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and 4-heptylphenol, branched and linear (RP-HP)	939-460-0	1471311-26-8		yes
Nonylphenol, ethoxylated (polymer)	938-618-6	-		yes
Zirconia Aluminosilicate Refractory Ceramic Fibres	936-037-2	-		yes
proteases with the exception of those specified elsewhere in this Annex show/hide Proteinase, Staphylococcus aureus serine EC / List no: 259-611-8 \| CAS no: 55354-32-0 Proteinase, serine EC / List no: 253-431-3 \| CAS no: 37259-58-8 Proteinase, Agkistrodon serine EC / List no: 232-933-6 \| CAS no: 9046-56-4 Proteinase, rhizopus acid EC / List no: 812-486-9 \| CAS no: 9074-09-3 Proteinase, Aspergillus acid EC / List no: 232-796-2 \| CAS no: 9025-49-4 Proteinase, Bacillus alcalophilus serine EC / List no: 306-090-0 \| CAS no: 95979-76-3 Proteinase, microbial alkaline EC / List no: 256-863-0 \| CAS no: 50936-53-3 Proteinase, Serratia extracellular EC / List no: 253-457-5 \| CAS no: 37312-62-2 Proteinase, microbial acid EC / List no: 256-862-5 \| CAS no: 50936-52-2 Proteinase, Endothia aspartic EC / List no: 253-395-9 \| CAS no: 37205-60-0 Proteinase, bacterial E 30 serine EC / List no: - \| CAS no: 39369-34-1 Proteinase, aspartic EC / List no: 278-856-1 \| CAS no: 78169-47-8 Proteinase, Aspergillus melleus, semialkaline EC / List no: - \| CAS no: 76106-83-7 Proteinase, microbial neutral EC / List no: 232-966-6 \| CAS no: 9068-59-1 Proteinase, Myxobacter α-lytic EC / List no: 253-448-6 \| CAS no: 37288-76-9 Proteinase, Streptomyces griseus EC / List no: 232-909-5 \| CAS no: 9036-06-0 Proteinase, Bacillus polymyxa neutral EC / List no: 255-914-4 \| CAS no: 42613-33-2 Amylase, mixture with proteinase EC / List no: 685-079-5 \| CAS no: 9001-11-0 Aspergillin M EC / List no: - \| CAS no: 42615-60-1 Proteinase, Aspergillus alkaline EC / List no: 232-977-6 \| CAS no: 9074-07-1 Proteinase, Bacillus licheniformis serine EC / List no: 279-361-3 \| CAS no: 79986-26-8 Proteinase, serine (Tritirachium album) EC / List no: 686-165-5 \| CAS no: 102925-54-2 Proteinase, Myxobacter AL-1, II EC / List no: 276-716-4 \| CAS no: 72561-05-8 Proteinase, oryzin EC / List no: 232-992-8 \| CAS no: 9081-30-5 Proteinase, Bacillus subtilis EC / List no: 257-520-8 \| CAS no: 51931-23-8 Proteinase, Mucor aspartic EC / List no: 232-975-5 \| CAS no: 9073-79-4 Amylase, mixed with proteinase, Bacillus cereus-fermented EC / List no: - \| CAS no: 68909-35-3 Proteinase, Bacillus subtilis metallo- EC / List no: 232-991-2 \| CAS no: 9080-56-2 Myxobacteralphalyticproteinase EC / List no: - \| CAS no: 12585-31-8 Proteinase, Aspergillus niger neutral EC / List no: 254-422-7 \| CAS no: 39346-39-9 Proteinase, Bothrops atrox serine EC / List no: 232-918-4 \| CAS no: 9039-61-6 Proteinase, Tritirachium album serine EC / List no: 254-457-8 \| CAS no: 39450-01-6 Proteinase, Bacillus neutral EC / List no: 278-547-1 \| CAS no: 76774-43-1 Proteinase, Aspergillus parasiticus neutral EC / List no: 254-418-5 \| CAS no: 39335-09-6 Amylase, mixed with proteinase, Bacillus thuringiensis-fermented EC / List no: - \| CAS no: 68909-36-4 Proteinase, Aspergillus oryzae neutral EC / List no: 232-990-7 \| CAS no: 9080-55-1 Proteinase, Bacillus subtilis, sutilain EC / List no: 235-390-3 \| CAS no: 12211-28-8 Proteinase, submandibular gland serine, A EC / List no: 279-893-6 \| CAS no: 82047-85-6 Bacteria, complex with amylase and proteinase EC / List no: - \| CAS no: 68920-42-3 Bacillus megaterium protease fermentation product EC / List no: - \| CAS no: 68909-17-1 Proteinase, Bacillus subtilis serine EC / List no: 266-557-9 \| CAS no: 67051-83-6 Proteinase, Aspergillus neutral EC / List no: 278-588-5 \| CAS no: 77000-13-6 Thrombin EC / List no: 232-648-7 \| CAS no: 9002-04-4 Proteinase, Bacillus alkaline EC / List no: 232-972-9 \| CAS no: 9073-77-2 Proteinase, pancreatic EC / List no: 232-626-7 \| CAS no: 9001-72-3	934-013-6	39450-01-6	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Nonylphenolpolyglycolether	932-998-7	-		yes
Nonylphenol, ethoxylated (15-EO) (9016-45-9)	931-756-8	-		yes
Nonylphenol, ethoxylated (10-EO) (9016-45-9)	931-755-2	-		yes
Nonylphenol, ethoxylated (8-EO) (9016-45-9)	931-754-7	-		yes
Nonylphenol, ethoxylated (6,5-EO) (9016-45-9)	931-753-1	-		yes
Reaction mass of 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate and 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; reaction mass of DOTE and MOTE	915-270-3	-		yes
(2RS)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol; mefentrifluconazole	822-682-6	1417782-03-6	Skin Sens. 1
N-methoxy-N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-3-(difluoromethyl)- 1-methylpyrazole-4-carboxamide; pydiflumetofen	817-852-1	1228284-64-7	Carc. 2; Repr. 2
(RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; medetomidine	811-718-6	86347-14-0	Acute Tox. 2; STOT SE 3; STOT SE 1; STOT RE 1
sulfoxaflor (ISO); [methyl(oxo) {1-[6-(trifluoromethyl)-3-pyridyl]ethyl}-λ6-sulfanylidene]cyanamide	807-366-8	946578-00-3	Acute Tox. 4
4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one; flupyradifurone	804-373-8	951659-40-8	Acute Tox. 4; STOT RE 2
Tris(4-nonylphenyl, branched) phosphite show/hide Phenol, p-sec-nonyl-, phosphite EC / List no: - \| CAS no: 106599-06-8 Tris(nonylphenyl) phosphite EC / List no: 247-759-6 \| CAS no: 26523-78-4 Phenol, 4-nonyl-, phosphite (3:1) EC / List no: 608-492-4 \| CAS no: 3050-88-2 Phenol, p-isononyl-, phosphite (3:1) EC / List no: - \| CAS no: 31631-13-7 tris(4-nonylphenyl, branched) phosphite EC / List no: 701-028-2 \| CAS no: -	799-976-5	-		yes
Dioctyltin dilaurate, stannane, dioctyl-, bis(coco acyloxy) derivs., and any other stannane, dioctyl-, bis(fatty acyloxy) derivs. wherein C12 is the predominant carbon number of the fatty acyloxy moiety show/hide dioctyltin dilaurate; stannane, dioctyl-, bis(coco acyloxy) derivs. EC / List no: - \| CAS no: - Stannane, dioctyl-, bis(coco acyloxy) derivs. EC / List no: 293-901-5 \| CAS no: 91648-39-4 Dioctyltin dilaurate EC / List no: 222-883-3 \| CAS no: 3648-18-8	799-973-9	-		yes
Phenol, alkylation products (mainly in para position) with C12-rich branched alkyl chains from oligomerisation, covering any individual isomers and/ or combinations thereof (PDDP) show/hide Phenol, (tetrapropenyl) derivatives EC / List no: 616-100-8 \| CAS no: 74499-35-7 Phenol, 4-isododecyl- EC / List no: 608-055-8 \| CAS no: 27147-75-7 Phenol, dodecyl-, branched EC / List no: 310-154-3 \| CAS no: 121158-58-5 Phenol, tetrapropylene- EC / List no: - \| CAS no: 57427-55-1 [No public or meaningful name is available] EC / List no: - \| CAS no: 27459-10-5 Phenol, 4-dodecyl, branched EC / List no: 640-104-9 \| CAS no: 210555-94-5	799-972-3	-		yes
Medium-chain chlorinated paraffins (MCCP) UVCB substances consisting of more than or equal to 80% linear chloroalkanes with carbon chain lengths within the range from C14 to C17 show/hide Alkanes, C14-16, chloro EC / List no: 701-376-5 \| CAS no: 1372804-76-6 di-, tri- and tetrachlorotetradecane EC / List no: 950-299-5 \| CAS no: - Alkanes, C14-17, chloro EC / List no: 287-477-0 \| CAS no: 85535-85-9 Tetradecane, chloro derivs. EC / List no: - \| CAS no: 198840-65-2	799-971-8	-		yes
2-(4-tert-Butylbenzyl)propionaldehyde and its individual stereoisomers show/hide 2-(4-tert-butylbenzyl)propionaldehyde EC / List no: 201-289-8 \| CAS no: 80-54-6 (2R)-3-(4-tert-butylphenyl)-2-methylpropanal EC / List no: - \| CAS no: 75166-31-3 (2S)-3-(4-tert-butylphenyl)-2-methylpropanal EC / List no: - \| CAS no: 75166-30-2	799-970-2	-		yes
metaflumizone (ISO); (EZ)-2-[2-(4-cyanophe-nyl)-1-(a,a,a -trifluoro-m-tolyl)ethylidene]-[4-(tri-fluoromethoxy)phenyl] carbanilohydrazide [E-iso-mer > 90 %, Z-isomer <10 % relative content]; [1] (E)-2-[2-(4-cyanophenyl)-1-(a,a,a -trifluoro-m-tolyl) ethylidene]-[4-(trifluoro-methoxy)phenyl]carbani-lohydrazide [2]	701-454-9	852403-68-0	Repr. 2; Lact.; STOT RE 2
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one	701-394-3	1782069-81-1		yes
Alkanes, C14-16, chloro	701-376-5	1372804-76-6		yes
(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy} ethyl methyl carbonate; tolpyralate	701-225-3	1101132-67-5	Carc. 2; Repr. 2; STOT RE 2
phenol, 3-dodecyl-, branched	701-107-1	1801269-77-1	Repr. 1B; Skin Corr. 1C; Eye Dam. 1
phenol, 2-dodecyl-, branched	701-105-0	1801269-80-6	Repr. 1B; Skin Corr. 1C; Eye Dam. 1
Ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate	700-242-3	62037-80-3		yes
2-methyl-1,2-benzothiazol-3(2H)-one; [MBIT]	695-989-4	2527-66-4	Acute Tox. 4; Acute Tox. 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1A
(5-chloro-2-methoxy-4-methyl-3-pyridyl) (4,5,6-trimethoxy-o-tolyl)methanone; pyriofenone	692-456-8	688046-61-9	Carc. 2
benzovindiflupyr (ISO); N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	691-719-4	1072957-71-1	Acute Tox. 3
N-{2-[[1,1'-bi (cyclopropyl)]-2-yl] phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide; sedaxane	688-331-2	874967-67-6	Carc. 2
2-{2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethoxy}ethanol	687-833-9	1119449-38-5		yes
2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethanol	687-832-3	1119449-37-4		yes
di-L-para-menthene	686-814-2	34363-01-4	Skin Irrit. 2; Skin Sens. 1
tetracopper hexahydroxide sulphate hydrate	682-362-5	12527-76-3	Acute Tox. 4
trinexapac-ethyl (ISO); ethyl 4-[cyclopropyl (hydroxy) methylene]-3,5-dioxocyclohexanecarboxylate	680-302-2	95266-40-3	STOT RE 2; Skin Sens. 1B
amisulbrom (ISO); 3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide	672-776-4	348635-87-0	Carc. 2; Eye Irrit. 2
cyflumetofen (ISO); 2-methoxyethyl (RS)-2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-(α,α,α-trifluoro-o-tolyl)propionate	642-974-5	400882-07-7	Carc. 2; Skin Sens. 1A
hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI); reaction mass of 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde and 3-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde	641-410-5	130066-44-3	Skin Sens. 1A
Cadmium chloride, hydrate (2:5)	640-998-0	7790-78-5		yes
phenol, 4-dodecyl-, branched	640-104-9	210555-94-5	Repr. 1B; Skin Corr. 1C; Eye Dam. 1	yes
α-hydroxypoly(methyl-(3-(2,2,6,6-tetramethylpiperidin-4-yloxy)propyl)siloxane)	639-478-6	182635-99-0	Acute Tox. 4; Skin Corr. 1B
4-(3-ethylheptan-2-yl)phenol	635-696-0	186825-39-8		yes
4-(3,6-dimethylheptan-3-yl)phenol	635-391-2	142731-63-3		yes
4-(3,5-dimethylheptan-3-yl)phenol	635-389-1	186825-36-5		yes
4-(2,6-dimethylheptan-2-yl)phenol	635-388-6	521947-27-3		yes
pinoxaden (ISO); 8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropanoate	635-361-9	243973-20-8	Repr. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Sens. 1A
methacrifos (ISO); methyl (E)-3-[(dimethoxyphosphinothioyl)oxy]methacrylate	630-448-8	62610-77-9	Acute Tox. 4; Skin Sens. 1
Sulphuric acid, cadmium salt (1:1), unspecified hydration rate	626-360-4	15244-35-6		yes
3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA)	622-370-8	1522-92-5		yes
4-tert-Octylphenol monoethoxylate	621-345-9	2315-67-5		yes
4-(1,1,3,3-Tetramethylbutyl)phenol, ethoxylated	621-341-7	2315-61-9		yes
erionite	620-440-2	12510-42-8	Carc. 1A
diclobutrazole (ISO);(R, R)-(±)-β-[(2,4-dichlorop henyl)methyl]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; (2RS, 3RS)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2- (1H—1,2,4-triazol-1yl)pentan-3-ol	620-436-0	75736-33-3	Eye Irrit. 2
propylenethiourea	620-432-9	2122-19-2	Repr. 2; Acute Tox. 4
guazatine (ISO)	620-427-1	108173-90-6	Acute Tox. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
azafenidin (ISO); 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one	620-425-0	68049-83-2	Repr. 1B; STOT RE 2
dinosam (ISO); 2-(1-methylbutyl)-4,6-dinitrophenol	620-422-4	4097-36-3	Acute Tox. 3
2,4,6-trinitroanisole	620-419-8	606-35-9	Expl. 1.1; Acute Tox. 4
8,9-dinorborn-5-ene-2,3-dicarboxylic anhydride	620-411-4	123748-85-6	Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
kelevan (ISO); ethyl 5-(perchloro-5-hydroxypentacyclo[5,3,0,02,6,03,9,04,8]decan-5-yl)-4-oxopentanoate; ethyl 5-(1,2,3,5,6,7,8,9,10,10-decachloro-4-hydroxypentacyclo(5,2,1,02,6,03,9,05,8)dec-4-yl)-4-oxovalerate	620-410-9	4234-79-1	Acute Tox. 3; Acute Tox. 4
dichloroacetylene	620-404-6	7572-29-4	Unst. Expl.; Carc. 2; STOT RE 2
basic phenylmercury nitrate	620-403-0	8003-05-2	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
lithium nickel dioxide	620-400-4	12031-65-1	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt nickel oxide	620-395-9	12737-30-3	Carc. 1A; STOT RE 1; Skin Sens. 1
dimethyl 4-(methylthio)phenyl phosphate	620-379-1	3254-63-5	Acute Tox. 1; Acute Tox. 2
demeton	620-378-6	8065-48-3	Acute Tox. 1; Acute Tox. 2
cyanofenphos (ISO); O-4-cyanophenyl O-ethyl phenylphosphonothioate	620-377-0	13067-93-1	Acute Tox. 3; STOT SE 1; Acute Tox. 4; Eye Irrit. 2
S-[2-(ethylsulphinyl)ethyl] O,O-dimethyl phosphorodithioate	620-370-2	2703-37-9	Acute Tox. 2; Acute Tox. 1
triamiphos (ISO); 5-amino-3-phenyl-1,2,4-triazol-1-yl-N, N,N',N'-tetramethylphosphonic diamide	620-368-1	1031-47-6	Acute Tox. 1; Acute Tox. 2
propineb (ISO); polymeric zinc propylenebis(dithiocarbamate)	620-365-5	9016-72-2	Acute Tox. 4; STOT RE 2; Skin Sens. 1
methyl 3,4-dichlorophenylcarbanilate; SWEP.	620-362-9	1918-18-9	Acute Tox. 4
bufencarb (ISO); reaction mass of 3-(1-methylbutyl)phenyl N-methylcarbamate and 3-(1-ethylpropyl)phenyl N-methylcarbamate	620-359-2	8065-36-9	Acute Tox. 3
3-(4-chlorophenyl)-1,1-dimethyluronium trichloroacetate; monuron-TCA	620-358-7	140-41-0	Carc. 2; Eye Irrit. 2; Skin Irrit. 2
3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide; fluxapyroxad	620-041-3	907204-31-3	Lact.
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide; penflufen	619-823-7	494793-67-8	Carc. 2
clethodim (ISO); (5RS)-2-{(1EZ)-1-[(2E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylthio)propyl]-3-hydroxycyclohex-2-en-1-one	619-396-7	99129-21-2	Acute Tox. 4; Skin Sens. 1
sulcotrione (ISO); 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	619-394-6	99105-77-8	Repr. 2; STOT RE 2; Skin Sens. 1A
fosthiazate (ISO); (RS)-S-sec-butyl-O-ethyl-2-oxo-1,3-thiazolidin-3-ylphosphonothioate	619-377-3	98886-44-3	Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
ethametsulfuron-methyl (ISO); methyl 2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl] carbamoyl}sulfamoyl) benzoate	619-290-0	97780-06-8	Eye Irrit. 2
cyproconazole (ISO); (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl) butan-2-ol	619-020-1	94361-06-5	Repr. 1B; Acute Tox. 3; STOT RE 2
prosulfuron (ISO); 1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	619-000-2	94125-34-5	Acute Tox. 4
Polyethylene glycol mono(tert-octylph-enyl) ether9036-19-5	618-541-1	9036-19-5		yes
cellulose nitrate; nitrocellulose	618-392-2	9004-70-0	Expl. 1.1
2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol	618-344-0	9002-93-1		yes
tralkoxydim (ISO); 2-(N-ethoxypropanimidoyl)-3-hydroxy-5-mesitylcyclohex-2-en-1-one	618-075-9	87820-88-0	Carc. 2; Acute Tox. 4
S-metolachlor; reaction mass of (S)-2-chloro-N-(2-ethyl-6-methyl-phenyl)-N-(2-methoxy-1-methyl-ethyl)-acetamide (80-100 %)	618-004-1	87392-12-9	Skin Sens. 1
flusilazole (ISO); bis(4-fluorophenyl)(methyl)(1H-1,2,4-triazol-1-ylmethyl)silane	617-717-5	85509-19-9	Carc. 2; Repr. 1B; Acute Tox. 4
diniconazole (ISO);(E)-β-[(2,4-dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H—1,2,4-triazol-1- ethanol;(E)-(RS)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H—1,2,4- triazol-1-yl)pent-1-en-3-ol	617-485-5	76714-88-0	Acute Tox. 4
bifenthrin (ISO); (2-methylbiphenyl-3-yl)methylrel-(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	617-373-6	82657-04-3	Carc. 2; Acute Tox. 3; Acute Tox. 2; STOT RE 1; Skin Sens. 1B
benfuracarb (ISO); ethyl N-[2,3-dihydro-2,2-dimethylbenzofuran-7-yloxycarbonyl(methyl)aminothio]-N-isopropyl-β-alaninate	617-356-3	82560-54-1	Repr. 2; Acute Tox. 3; Acute Tox. 4
clomazone (ISO); 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one	617-258-0	81777-89-1	Acute Tox. 4
glyphosate-trimesium; glyphosate-trimethylsulfonium	617-243-9	81591-81-3	Acute Tox. 4
imazapyr (ISO);2-[4,5-dihydro-4-methyl-4-(1- methylethyl)-5-oxo-1H- imidazol-2-yl]-3-pyridine carboxylate	617-219-8	81334-34-1	Eye Irrit. 2
sabadilla (ISO);veratrine	617-100-0	8051-02-3	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt	616-995-5	8018-01-7	Carc. 2; Repr. 1B; STOT RE 2; Skin Sens. 1
bordeaux mixture; reaction products of copper sulphate with calcium dihydroxide	616-932-1	8011-63-0	Acute Tox. 4; Eye Dam. 1
fluazinam (ISO); 3-chloro-N-[3- chloro-2,6-dinitro-4-(trifluor omethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	616-712-5	79622-59-6	Repr. 2; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1A
tefluthrin (ISO); 2,3,5,6-tetrafluoro-4-methylbenzyl (1RS,3RS)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropanecarboxylate	616-699-6	79538-32-2	Acute Tox. 1; Acute Tox. 2
fluazifop-P-butyl (ISO); butyl (R)-2-[4-(5-trifluoromethyl-2-pyridyloxy)phenoxy]propionate	616-669-2	79241-46-6	Repr. 2
Hydrazine hydrate	616-584-0	7803-57-8		yes
Sulfuric acid, cadmium salt (1:1), hydrate (3:8)	616-572-5	7790-84-3		yes
Sodium dichromate	616-541-6	7789-12-0		yes
iron (II) sulfate (1:1) heptahydrate; sulfuric acid, iron(II) salt (1:1), heptahydrate; ferrous sulfate heptahydrate	616-510-7	7782-63-0	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
copper sulphate pentahydrate	616-477-9	7758-99-8	Acute Tox. 4; Eye Dam. 1
asbestos	616-473-7	77536-68-6	Carc. 1A; STOT RE 1
asbestos	616-472-1	77536-67-5	Carc. 1A; STOT RE 1
asbestos	616-471-6	77536-66-4	Carc. 1A; STOT RE 1
paclobutrazol (ISO); (2RS,3RS)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	616-379-6	76738-62-0	Repr. 2; Acute Tox. 4; Eye Irrit. 2
(E)-(7R,11R)-3,7,11,15-tetramethylhexadec-2-ene-1-ol	616-221-6	7541-49-3	Skin Irrit. 2
phenol, (tetrapropenyl) derivatives	616-100-8	74499-35-7	Repr. 1B; Skin Corr. 1C; Eye Dam. 1	yes
zinc sulphate (hydrous) (mono-, hexa-and hepta hydrate)	616-096-8	7446-19-7	Acute Tox. 4; Eye Dam. 1
abamectin (combination of avermectin B1a and avermectin B1b) (ISO)	615-339-5	71751-41-2	Repr. 2; Acute Tox. 2; Acute Tox. 1; STOT RE 1
fenoxaprop-P-ethyl (ISO); ethyl (2R)-2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}propanoate	615-273-7	71283-80-2	STOT RE 2; Skin Sens. 1
metalaxyl-M (ISO); mefenoxam; (R)-2-[(2,6-dimethylphenyl)-methoxyacetylamino]propionic acid methyl ester	615-135-6	70630-17-0	Acute Tox. 4; Eye Dam. 1
triflumizole (ISO); (1E)-N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(1H-imidazol-1-yl)-2-propoxyethanimine	614-708-8	68694-11-1	Repr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
forchlorfenuron (ISO); 1-(2-chloro-4-pyridyl)-3-phenylurea	614-346-0	68157-60-8	Carc. 2
α-cypermethrin (ISO); racemate comprising (R)-α-cyano-3-phenoxybenzyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; (S)-α-cyano-3-phenoxybenzyl(1R, 3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	614-054-3	67375-30-8	Acute Tox. 3; STOT RE 2; STOT SE 3
potassium (oxido-NNO-azoxy)cyclohexane; cyclohexylhydroxydiazene 1-oxide, potassium salt; [K-HDO]	613-953-8	66603-10-9	Flam. Sol. 1; Acute Tox. 3; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
esfenvalerate (ISO); (S)-α-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-3-methylbutyrate	613-911-9	66230-04-4	Acute Tox. 3; STOT SE 1; STOT RE 2; Skin Sens. 1
flumetralin (ISO); N-(2-chloro-6-fluorobenzyl)-N-ethyl-α, α,α-trifluoro-2,6-dinitro-p-toluidine	613-108-3	62924-70-3	Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
sec-butyl propionate	611-802-0	591-34-4	Flam. Liq. 3
acequinocyl (ISO); 3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	611-595-7	57960-19-7	Skin Sens. 1; STOT SE 1; STOT RE 2
pyroquilon (ISO);1,2,5,6-tetrahydropyrrolo[3,2,1- ij]quinolin-4-one	611-516-6	57369-32-1	Acute Tox. 4
reaction mass of: 5-chloro-2-methyl-4-isothiazolin-3-one [EC no. 247-500-7]and 2-methyl-2H-isothiazol-3-one [EC no. 220-239-6] (3:1); reaction mass of: 5-chloro-2-methyl-4-isothiazolin-3-one [EC no. 247-500-7]and 2-methyl-4-isothiazolin-3-one [EC no. 220-239-6] (3:1)	611-341-5	55965-84-9	Acute Tox. 2; Acute Tox. 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1A
ethyl methyl ether	611-089-6	540-67-0	Flam. Gas 1; Press. Gas
troclosene sodium, dihydrate	610-700-3	51580-86-0	Acute Tox. 4; Eye Irrit. 2; STOT SE 3
pyroxsulam (ISO); N-(5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	610-007-6	422556-08-9	Skin Sens. 1
Isononylphenol, ethoxylated	609-346-2	37205-87-1		yes
tembotrione (ISO); 2-{2- chloro-4-(methylsulfonyl)-3- [(2,2,2-trifluoroethoxy)methyl] benzoyl}cyclohexane-1,3-dione	608-879-8	335104-84-2	Repr. 2; STOT RE 2; Skin Sens. 1
polyhexamethylene biguanide hydrochloride; PHMB	608-723-9	32289-58-0	Carc. 2; Acute Tox. 2; Acute Tox. 4; STOT RE 1; Eye Dam. 1; Skin Sens. 1B
bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O')copper; bis(N-cyclohexyl-diazenium-dioxy)-copper; [Cu-HDO]	608-595-4	312600-89-8	Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
Phenol, 4-nonyl-, phosphite (3:1)	608-492-4	3050-88-2		yes
4-Isododecylphenol;Phenol, 4-isododecyl	608-055-8	27147-75-7;27459-10-5		yes
4-Isododecylphenol;Phenol, 4-isododecyl	608-055-8	27147-75-7;27459-10-5		yes
polyhexamethylene biguanide hydrochloride; PHMB	608-042-7	27083-27-8	Carc. 2; Acute Tox. 2; Acute Tox. 4; STOT RE 1; Eye Dam. 1; Skin Sens. 1B
XMC; 3,5-xylyl methylcarbamate	607-955-8	2655-14-3	Acute Tox. 4
piperophos (ISO); S-2-methylpiperidinocarbonylmethyl-O, O-dipropyl phosphorodithioate	607-329-4	24151-93-7	Acute Tox. 4
3-(3-amino-5-(1-methylguanidino)-1-oxopentylamino-6-(4-amino-2-oxo-2,3-dihydro-pyrimidin-1-yl)-2,3-dihydro-(6H)-pyran-2-carboxylic acid; blasticidin-s	606-640-2	2079-00-7	Acute Tox. 2
tert-butyl propionate	606-566-0	20487-40-5	Flam. Liq. 2
spirotetramat (ISO); (5s,8s)-3- (2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4,5]dec- 3-en-4-yl ethyl carbonate	606-523-6	203313-25-1	Repr. 2; STOT SE 3; Eye Irrit. 2; Skin Sens. 1A
proquinazid (ISO); 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	606-168-7	189278-12-4	Carc. 2
bensultap (ISO); 1,3-bis(phenylsulfonylthio)-2-(N,N-dimethylamino)propane	605-769-1	17606-31-4	Acute Tox. 4
silthiofam (ISO); N-allyl-4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxamide	605-752-9	175217-20-6	STOT RE 2
pyraclostrobin (ISO); methyl N-{2-[1-(4-chlorophenyl)-1H-pyrazol-3-yloxymethyl]phenyl}(N-methoxy)carbamate	605-747-1	175013-18-0	Acute Tox. 3; Skin Irrit. 2
indoxacarb (ISO); methyl (4aS)-7-chloro-2-{(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]carbamoyl}-2,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate	605-683-4	173584-44-6	Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Sens. 1B
dimethenamid-P (ISO); 2-chloro-N-(2,4-dimethyl-3- thienyl)-N-[(2S)-1-methoxypropan-2-yl]acetamide	605-329-9	163515-14-8	Acute Tox. 4; Skin Sens. 1
flonicamid (ISO); N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	605-127-0	158062-67-0	Acute Tox. 4
zoxamide (ISO); (RS)-3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide	605-037-1	156052-68-5	Skin Sens. 1
emamectin benzoate (ISO); (4''R)-4''-deoxy-4''-(methylamino) avermectin B1 benzoate	605-015-1	155569-91-8	Acute Tox. 3; STOT SE 1; STOT RE 1; Eye Dam. 1
tepraloxydim (ISO); (RS)-(EZ)-2-{1-[(2E)-3-chloroallyloxyimino]propyl}-3-hydroxy-5-perhydropyran-4-ylcyclohex-2-en-1-one	604-715-4	149979-41-9	Carc. 2; Repr. 2
dimoxystrobin (ISO); (E)-2-(methoxyimino)-N-methyl-2-[α-(2,5-xylyloxy)-o-tolyl]acetamide	604-712-8	149961-52-4	Carc. 2; Repr. 2; Acute Tox. 4
spirodiclofen (ISO); 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutyrate	604-636-5	148477-71-8	Carc. 1B; Repr. 2; STOT RE 2; Skin Sens. 1B
oxasulfuron (ISO); oxetan-3-yl 2-[(4,6-dimethylpyrimidin-2-yl)-carbamoylsulfamoyl]benzoate	604-430-5	144651-06-9	STOT RE 2
reaction mass of (S)-Indoxacarb and (R)-Indoxacarb 75:25; methyl 7-chloro-2-{(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]carbamoyl}-2,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate [2]	604-398-2	144171-61-9	Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Sens. 1B
26-(4-nonylphenoxy)-3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol	604-395-6	14409-72-4		yes
kresoxim-methyl (ISO); methyl (E)-2-methoxyimino-[2-(o-tolyloxymethyl)phenyl]acetate	604-351-6	143390-89-0	Carc. 2
cinidon ethyl (ISO); ethyl (Z)-2-chloro-3-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboximido)phenyl]acrylate	604-318-6	142891-20-1	Carc. 2; Skin Sens. 1
Aluminosilicate Refractory Ceramic Fibres	604-314-4	142844-00-6		yes
tritosulfuron (ISO) (containing ≤0,02 % AMTT); 1-[4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]-3-[2-(trifluoromethyl)benzenesulfonyl]urea (containing ≤ 0,02 % AMTT)	604-291-0	142469-14-5	Skin Sens. 1
flufenacet (ISO);N-(4-fluorophenyl)-N-isopropyl-2-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)acetamide	604-290-5	142459-58-3	Acute Tox. 4; STOT RE 2; Skin Sens. 1
trifloxystrobin (ISO); methyl (E)-methoxyimino-{(E)-α-[1-(α,α,α-trifluoro-m-tolyl) ethylideneaminooxy]-o-tolyl}acetate	604-237-6	141517-21-7	Lact.; Skin Sens. 1
isoxaflutole (ISO); 5-cyclopropyl-1,2-oxazol-4-yl α,α,α-trifluoro-2-mesyl-p-tolyl ketone	604-222-4	141112-29-0	Repr. 2
iprovalicarb (ISO); isopropyl [(2S)-3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl]carbamate	604-209-3	140923-17-7	Carc. 2
metaflumizone (ISO); (EZ)-2-[2-(4-cyanophe-nyl)-1-(a,a,a -trifluoro-m-tolyl)ethylidene]-[4-(tri-fluoromethoxy)phenyl] carbanilohydrazide [E-iso-mer > 90 %, Z-isomer <10 % relative content]; [1] (E)-2-[2-(4-cyanophenyl)-1-(a,a,a -trifluoro-m-tolyl) ethylidene]-[4-(trifluoro-methoxy)phenyl]carbani-lohydrazide [2]	604-167-6	139968-49-3	Repr. 2; Lact.; STOT RE 2
profoxydim (ISO); 2-{(EZ)-1-[(2RS)-2-(4-chlorophenoxy)propoxyimino]butyl}-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-one	604-105-8	139001-49-3	Carc. 2; Repr. 2; Skin Sens. 1
acetamiprid (ISO); (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine	603-921-1	135410-20-7	Acute Tox. 4
Perboric acid (H3BO2(O2)), monosodium salt, trihydrate;perboric acid (H3BO2(O2)), monosodium salt trihydrate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];perboric acid (H3BO2(O2)), monosodium salt, trihydrate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]	603-902-8	13517-20-9		yes
Perboric acid (H3BO2(O2)), monosodium salt, trihydrate;perboric acid (H3BO2(O2)), monosodium salt trihydrate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];perboric acid (H3BO2(O2)), monosodium salt, trihydrate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]	603-902-8	13517-20-9	Repr. 1B; STOT SE 3; Eye Dam. 1
Perboric acid (H3BO2(O2)), monosodium salt, trihydrate;perboric acid (H3BO2(O2)), monosodium salt trihydrate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];perboric acid (H3BO2(O2)), monosodium salt, trihydrate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]	603-902-8	13517-20-9	Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Gamma-hexabromocyclododecane	603-804-5	134237-52-8		yes
Beta-hexabromocyclododecane	603-802-4	134237-51-7		yes
Alpha-hexabromocyclododecane	603-801-9	134237-50-6		yes
fenpyroximate (ISO); tert-butyl 4-[({(E)-[(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino}oxy)methyl]benzoate	603-792-1	134098-61-6	Acute Tox. 3; Acute Tox. 2; Skin Sens. 1B
azoxystrobin (ISO); methyl (E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl}-3-methoxyacrylate	603-524-3	131860-33-8	Acute Tox. 3
famoxadone (ISO); 3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	603-520-1	131807-57-3	STOT RE 2
disodium tetraborate decahydrate	603-411-9	1303-96-4	Repr. 1B	yes
silver zinc zeolite (Zeolite, LTA framework type, surface-modified with silver and zinc ions)	603-404-0	130328-20-0	Repr. 2; Skin Irrit. 2; Eye Dam. 1
triflusulfuron-methyl; methyl 2-({[4-(dimethylamino)-6- (2,2,2-trifluoroethoxy)-1,3,5- triazin-2-yl]carbamoyl}sulfamoyl)-3-methylbenzoate	603-146-9	126535-15-7	Carc. 2
ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	603-038-1	125225-28-7	Repr. 1B; Acute Tox. 4; STOT RE 2
metconazole (ISO); (1RS, 5RS;1RS, 5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	603-031-3	125116-23-6	Repr. 2; Acute Tox. 4
quinoxyfen (ISO);5,7-dichloro-4-(4-fluorophenoxy)quinoline	602-997-3	124495-18-7	Skin Sens. 1
1-hydroxybenzotriazole, monohydrated	602-929-2	123333-53-9	Expl. 1.3
pymetrozine (ISO); (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one	602-927-1	123312-89-0	Carc. 2; Repr. 2
disodium octaborate tetrahydrate	602-894-3	12280-03-4	Repr. 1B
chlorfenapyr (ISO); 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile	602-782-4	122453-73-0	Acute Tox. 3; Acute Tox. 4
white phosphorus	601-810-2	12185-10-3	Pyr. Sol. 1; Acute Tox. 2; Skin Corr. 1A
Disodium tetraborate pentahydrate	601-808-1	12179-04-3	Repr. 1B	yes
asbestos	601-801-3	12172-73-5	Carc. 1A; STOT RE 1
cyprodinil (ISO); 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	601-785-8	121552-61-2	Skin Sens. 1
asbestos	601-650-3	12001-29-5	Carc. 1A; STOT RE 1
asbestos	601-649-8	12001-28-4	Carc. 1A; STOT RE 1
tebufenpyrad (ISO); N-(4-tertbutylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	601-585-0	119168-77-3	Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1B
spiroxamine (ISO); 8-tert-butyl-1,4-dioxaspiro[4.5]decan-2-ylmethyl(ethyl)(propyl)amine	601-505-4	118134-30-8	Repr. 2; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1
imazamox (ISO); (RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid	601-305-7	114311-32-9	Repr. 2
thiacloprid (ISO); (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidenecyanamide; {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide	601-147-9	111988-49-9	Carc. 2; Repr. 1B; Acute Tox. 4; Acute Tox. 3; STOT SE 3
pethoxamide (ISO); 2-chloro-N-(2-ethoxyethyl)-N-(2-methyl-1-phenylprop-1enyl)acetamide	600-765-6	106700-29-2	Acute Tox. 4; Skin Sens. 1
clodinafop-propargyl (ISO)	600-662-6	105512-06-9	Acute Tox. 4; STOT RE 2; Skin Sens. 1

Prikazano 1 - 200 od 4.821 rezultata.

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EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

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Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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