EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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Prikazano 4.601 - 4.700 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC	EU REACH: List of SVHC
tin(II) methanesulphonate STANNOUS METHANE SULPHONAT; STANNOUS METHANE SULPHONATE; TIN (II) METHANE SULPHONATE; TIN METHANE SULPHONATE; TIN METHANESULFONATE; TIN SALT FS; ZINN(II) METHANESULFONATE; ZINN(II)-METHANSULFONAT	401-640-7	53408-94-9	Skin Corr. 1B; Acute Tox. 4; Skin Sens. 1
titanium dioxide [in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm]	236-675-5	13463-67-7	Carc. 2
titanium tetrachloride	231-441-9	7550-45-0	Skin Corr. 1B
titanium(4+) oxalate TITANYL OXALAAT	403-260-7	31363-92-5	Eye Dam. 1
tolclofos-methyl (ISO); O-(2,6-dichloro-p-tolyl)-O,O-dimethyl thiophosphate	260-515-3	57018-04-9	Skin Sens. 1B
toluene	203-625-9	108-88-3	Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; STOT SE 3
toluene-2,4-diammonium sulphate; 4-methyl-m-phenylenediamine sulfate	265-697-8	65321-67-7	Carc. 1B; Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
toluidine sulphate (1:1)	208-741-3	540-25-0	Carc. 2; Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
toluidinium chloride	208-740-8	540-23-8	Carc. 2; Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing ≥0.1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]	211-986-9	731-27-1	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing ≥0.1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]	211-986-9	731-27-1	Acute Tox. 2; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Tonate virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Toroviridae	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Toscana virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
tosylchloramide sodium	204-854-7	127-65-1	Acute Tox. 4; Skin Corr. 1B; Resp. Sens. 1
Toxocara canis	-	-		P Parasites
Toxoplasma gondii	-	-		P Parasites
tralkoxydim (ISO); 2-(N-ethoxypropanimidoyl)-3-hydroxy-5-mesitylcyclohex-2-en-1-one	618-075-9	87820-88-0	Carc. 2; Acute Tox. 4
trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide FC4010	417-290-3	147086-81-5	Acute Tox. 4
trans-(5RS,6SR)-6-amino-2,2-dimethyl-1,3-dioxepan-5-ol AMINODIOXEPAN	419-050-3	79944-37-9	Skin Sens. 1
trans-1-methyl-4-(1-methylvinyl)cyclohexene	229-977-3	6876-12-6	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
trans-2-isopropyl-5-carboxy-1,3-dioxane DHP OPT	445-770-2	42031-28-7	Eye Dam. 1
trans-2-methylcyclohexanol	231-186-3	7443-52-9	Acute Tox. 4
trans-4-cyclohexyl-L-proline monohydrochloride SQ28,646	419-160-1	90657-55-9	Repr. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
trans-4-phenyl-L-proline SQ 27,616	416-020-1	96314-26-0	Repr. 2; Skin Sens. 1
trans-cyclohexane-1,2-dicarboxylic anhydride	238-009-9	14166-21-3	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1		yes
trans-dichloroethylene	205-860-2	156-60-5	Flam. Liq. 2; Acute Tox. 4
trans-isopropyl-3-[[(ethylamino)methoxyfosfinothioyl]oxy]crotonate; isopropyl 3-[[(ethylamino)methoxyphosphinothioyl]oxy]isocrotonate; propetamphos (ISO)	250-517-2	31218-83-4	Acute Tox. 3
trans-methyl-2-ethyl-but-2-enoate	443-150-6	101226-85-1	Flam. Liq. 3
transfluthrin (ISO); 2,3,5,6-tetrafluorobenzyl trans-2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylate	405-060-5	118712-89-3	Skin Irrit. 2
trans—N-methyl-2-styryl-[4'- aminomethine-(1-acetyl-1-(2- methoxyphenyl)acetamido)]py ridinium acetate BASIC YELLOW 105; C.I. BASIC YELLOW 105	405-860-4	121315-16-0	Skin Sens. 1
Treponema carateum	-	-		B Bacteria and similar species
Treponema pallidum	-	-		B Bacteria and similar species
Treponema pertenue	-	-		B Bacteria and similar species
Treponema spp.	-	-		B Bacteria and similar species
tri-allate (ISO); S-2,3,3-trichloroallyl diisopropylthiocarbamate	218-962-7	2303-17-5	Acute Tox. 4; STOT RE 2; Skin Sens. 1
tri-methylamine;tri-methylamine ... %	200-875-0	75-50-3	Flam. Gas 1; Press. Gas; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
tri-methylamine;tri-methylamine ... %	200-875-0	75-50-3	Flam. Liq. 1; Acute Tox. 4; Skin Corr. 1B
triadimefon (ISO); 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butanone	256-103-8	43121-43-3	Acute Tox. 4; Skin Sens. 1
triadimenol (ISO); (1RS,2RS;1RS,2SR)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; α-tert-butyl-β-(4-chlorophenoxy)-1H-1,2,4-triazole-1-ethanol	259-537-6	55219-65-3	Repr. 1B; Lact.; Acute Tox. 4
trialkylboranes, solid	-	-	Pyr. Liq. 1; Skin Corr. 1B
triamiphos (ISO); 5-amino-3-phenyl-1,2,4-triazol-1-yl-N, N,N',N'-tetramethylphosphonic diamide	620-368-1	1031-47-6	Acute Tox. 1; Acute Tox. 2
triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate	432-270-4	221354-37-6	Repr. 2; STOT RE 2
triarimol (ISO); 2,4-dichloro-α-(pyrimidin-5-yl)benzhydryl alcohol	-	26766-27-8	Acute Tox. 4
triazophos (ISO); O, O-diethyl-O-1-phenyl-1H-1,2,4-triazol-3-yl phosphorothioate	245-986-5	24017-47-8	Acute Tox. 3; Acute Tox. 4
tribenuron-methyl (ISO); 2-[4-methoxy-6-methyl-1,3,5-triazin-2-yl(methyl)carbamoylsulfamoyl]benzoic acid methyl ester; methyl 2-(3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3methylureidosulfonyl)benzoate	401-190-1	101200-48-0	STOT RE 2; Skin Sens. 1
tributyl phosphate	204-800-2	126-73-8	Carc. 2; Acute Tox. 4; Skin Irrit. 2
tributyltetradecylphosphonium tetrafluoroborate D 27-046	413-520-1	125792-14-5	Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1
tributyltin compounds, with the exception of those specified elsewhere in this Annex	-	-	Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Irrit. 2; Eye Irrit. 2
Trichinella spiralis	-	-		P Parasites
trichlorfon (ISO); dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate	200-149-3	52-68-6	Acute Tox. 4; Skin Sens. 1
trichloro(methyl)silane; methyltrichlorosilane	200-902-6	75-79-6	Flam. Liq. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
trichloroacetonitrile	208-885-7	545-06-2	Acute Tox. 3
trichloroethylene; trichloroethene	201-167-4	79-01-6	Carc. 1B; Muta. 2; Eye Irrit. 2; Skin Irrit. 2; STOT SE 3		yes
trichloromethylstannane	213-608-8	993-16-8	Repr. 2
trichloronate (ISO); O-ethyl O-2,4,5-trichlorophenyl ethylphosphonothioate	206-326-1	327-98-0	Acute Tox. 2; Acute Tox. 3
trichloronitromethane; chloropicrin	200-930-9	76-06-2	Acute Tox. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
trichlorosilane	233-042-5	10025-78-2	Flam. Liq. 1; Pyr. Liq. 1; Acute Tox. 4; Skin Corr. 1A
Trichophyton rubrum	-	-		F Fungi
Trichophyton spp.	-	-		F Fungi
Trichuristrichiura	-	-		P Parasites
triclosan;2,4,4'-trichloro-2'-hydroxy-diphenyl-ether; 5-chloro-2-(2,4-dichlorophenoxy)phenol	222-182-2	3380-34-5	Eye Irrit. 2; Skin Irrit. 2
Tricosafluorododecanoic acid	206-203-2	307-55-1			yes
tricresyl phosphate (m-m-m-, m-m-p-, m-p-p-, p-p-p-); tritolyl phosphate (m-m-m-, m-m-p-, m-p-p-, p-p-p-);tricresyl phosphate (o-o-o-, o-o-m-, o-o-p-, o-m-m-, o-m-p-, o-p-p-); tritolyl phosphate (o-o-o-, o-o-m-, o-o-p-, o-m-m-, o-m-p-, o-p-p-)	215-548-8	1330-78-5	Acute Tox. 4
tricresyl phosphate (m-m-m-, m-m-p-, m-p-p-, p-p-p-); tritolyl phosphate (m-m-m-, m-m-p-, m-p-p-, p-p-p-);tricresyl phosphate (o-o-o-, o-o-m-, o-o-p-, o-m-m-, o-m-p-, o-p-p-); tritolyl phosphate (o-o-o-, o-o-m-, o-o-p-, o-m-m-, o-m-p-, o-p-p-)	215-548-8	1330-78-5	STOT SE 1
tricyclazole (ISO); 5-methyl-1,2,4-triazolo(3,4-b)benzo-1,3-thiazole	255-559-5	41814-78-2	Acute Tox. 4
Tridecafluorohexanesulphonic acid, compound with 2,2'-iminodiethanol (1:1)	274-462-9	70225-16-0			yes
tridemorph (ISO); 2,6-dimethyl-4-tridecylmorpholine	246-347-3	24602-86-6	Repr. 1B; Acute Tox. 4; Skin Irrit. 2
triethoxyisobutylsilane DYNASILAN BH N; DYNASILAN BSM 100 N; DYNASILAN NH 42	402-810-3	17980-47-1	Skin Irrit. 2
triethyl arsenate TRIETHYLARSENAT; TRIETHYLARSENATE; TRIETHYLARSENATE (TEASAT)	427-700-2	15606-95-8	Carc. 1A; Acute Tox. 3		yes
triethyl phosphate	201-114-5	78-40-0	Acute Tox. 4
triethylamine	204-469-4	121-44-8	Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
triethyltin compounds, with the exception of those specified elsewhere in this Annex	-	-	Acute Tox. 2; Acute Tox. 1
trifenmorph (ISO);4-tritylmorpholine	215-812-2	1420-06-0	Acute Tox. 4
trifloxystrobin (ISO); methyl (E)-methoxyimino-{(E)-α-[1-(α,α,α-trifluoro-m-tolyl) ethylideneaminooxy]-o-tolyl}acetate	604-237-6	141517-21-7	Lact.; Skin Sens. 1
triflumizole (ISO); (1E)-N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(1H-imidazol-1-yl)-2-propoxyethanimine	614-708-8	68694-11-1	Repr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
trifluoroacetic acid . . . %	200-929-3	76-05-1	Acute Tox. 4; Skin Corr. 1A
trifluoroiodomethane; trifluoromethyl iodide	219-014-5	2314-97-8	Muta. 2
trifluralin (ISO) (containing <0.5 ppm NPDA); α, α, α-trifluoro-2,6-dinitro-N, N-dipropyl-p-toluidine (containing; < 0,5 ppm NPDA); 2,6-dinitro-N, N-dipropyl-4-trifluoromethylaniline (containing < 0,5 ppm NPDA); N, N-dipropyl-2,6-dinitro-4-trifluoromethylaniline (containing < 0.5 ppm NPDA)	216-428-8	1582-09-8	Carc. 2; Skin Sens. 1
triflusulfuron-methyl; methyl 2-({[4-(dimethylamino)-6- (2,2,2-trifluoroethoxy)-1,3,5- triazin-2-yl]carbamoyl}sulfamoyl)-3-methylbenzoate	603-146-9	126535-15-7	Carc. 2
trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-)	235-688-3	12519-85-6	Carc. 1A; STOT RE 1; Skin Sens. 1
Trilead bis(carbonate)dihydroxide	215-290-6	1319-46-6			yes
trilead bis(orthophosphate)	231-205-5	7446-27-7	Repr. 1A; STOT RE 2
Trilead diarsenate	222-979-5	3687-31-8			yes
Trilead dioxide phosphonate	235-252-2	12141-20-7			yes
trilithium bis(4-((4-(diethylamino)-2-hydroxyphenyl)azo)-3-hydroxy-1-naphthalenesulfonato(3-))chromate(3-) ACID BLUE FC 77890	414-290-5	149564-65-8	Acute Tox. 4
trilithium-1-hydroxy-7-(3-sulfonatoanilino)-2-(3-methyl-4-(2-methoxy-4-(3-sulfonatophenylazo)phenylazo)phenylazo)naphthalene-3-sulfonate IJA-286; IJBK-286; IJBK-286-LI	403-650-7	117409-78-6	Expl. 1.3
trimethoxyvinylsilane; trimethoxy(vinyl)silane	220-449-8	2768-02-7	Skin Sens. 1B
trimethyl borate	204-468-9	121-43-7	Flam. Liq. 3; Acute Tox. 4
trimethylenediaminetetraacetic acid 1,3-PDTA; AGENT CHELATANT KODAK NO.1; DISSOLVINE PDZ; HAMPSHIRE PDTA; KODAK CHELATING AGENT NO.1; TRILON R FS	400-400-9	1939-36-2	Acute Tox. 4; Eye Dam. 1
trimethylopropane tri(3-aziridinylpropanoate); (TAZ)	257-765-0	52234-82-9	Muta. 2; Eye Dam. 1; Skin Sens. 1
trimethyltin compounds, with the exception of those specified elsewhere in this Annex	-	-	Acute Tox. 2; Acute Tox. 1
trinexapac-ethyl (ISO); ethyl 4-[cyclopropyl (hydroxy) methylene]-3,5-dioxocyclohexanecarboxylate	680-302-2	95266-40-3	STOT RE 2; Skin Sens. 1B
trinickel bis(arsenate); nickel(II) arsenate	236-771-7	13477-70-8	Carc. 1A; STOT RE 1; Skin Sens. 1
trinickel bis(arsenite)	-	74646-29-0	Carc. 1A; STOT RE 1; Skin Sens. 1
trinickel bis(orthophosphate)	233-844-5	10381-36-9	Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
trinickel boride	234-495-1	12007-02-2	Carc. 1A; STOT RE 1; Skin Sens. 1
trinickel disulfide; nickel subsulfide	234-829-6	12035-72-2	Carc. 1A; Muta. 2; Acute Tox. 3; STOT RE 1; Skin Sens. 1
trinickel tetrasulfide	-	12137-12-1	Carc. 1A; STOT RE 1; Skin Sens. 1
trioctylstannane TZ 02508	413-320-4	869-59-0	STOT RE 1; Skin Irrit. 2

Prikazano 4.601 - 4.700 od 4.821 rezultata.

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EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

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Last updated 26 srpnja 2024. Database contains 4821 unique substances/entries.

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