EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 06 rujna 2024. Database contains 4821 unique substances/entries.

Filter the list

Prikazano 3.101 - 3.200 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC	EU REACH: List of SVHC
Coltivirus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
colecalciferol; cholecalciferol; Vitamin D3	200-673-2	67-97-0	Acute Tox. 2; STOT RE 1
colchicine	200-598-5	64-86-8	Muta. 1B; Acute Tox. 2
Coccidioides inunitis	-	-		F Fungi
cobalt sulfide	215-273-3	1317-42-6	Skin Sens. 1
cobalt sulfate	233-334-2	10124-43-3	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1		yes
cobalt oxide	215-154-6	1307-96-6	Acute Tox. 4; Skin Sens. 1
cobalt nickel oxide	620-395-9	12737-30-3	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt nickel gray periclase; C.I. Pigment Black 25; C.I. 77332 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77332.	269-051-6	68186-89-0	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt nickel dioxide	261-346-8	58591-45-0	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt lithium nickel oxide	442-750-5	113066-89-0	Carc. 1A; Acute Tox. 2; STOT RE 1; Skin Sens. 1
cobalt dinitrate	233-402-1	10141-05-6	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1		yes
cobalt dimolybdenum nickel octaoxide	268-169-5	68016-03-5	Carc. 1A; STOT RE 1; Skin Sens. 1
cobalt dichloride	231-589-4	7646-79-9	Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1		yes
cobalt di(acetate)	200-755-8	71-48-7	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1		yes
cobalt carbonate	208-169-4	513-79-1	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1		yes
cobalt	231-158-0	7440-48-4	Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
Coal liquids, liq. solvent extn. soln. [The product obtained by filtration of coal mineral matter and undissolved coal from coal extract solution produced by digesting coal in a liquid solvent. A black, viscous, highly complex liquid combination composed primarily of aromatic and partly hydro-genated aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic and other aromatic oxygen compounds and their alkyl derivatives.] The product obtained by filtration of coal mineral matter and undissolved coal from coal extract solution produced by digesting coal in a liquid solvent. A black, viscous, highly complex liquid combination composed primarily of aromatic and partly hydrogenated aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic and other aromatic oxygen compounds and their alkyl derivatives.	302-682-8	94114-47-3	Carc. 1B
Coal liquids, liq. solvent extn. [The substantially solvent-free product obtained by the distillation of the solvent from filtered coal extract solution produced by digesting coal in a liquid solvent. A black semi-solid, composed primarily of a complex combination of condensed-ring aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic compounds and other aromatic oxygen compounds, and their alkyl derivatives.] The substantially solvent-free product obtained by the distillation of the solvent from filtered coal extract solution produced by digesting coal in a liquid solvent. A black semi-solid, composed primarily of a complex combination of condensed-ring aromatic hydrocarbons, aromatic nitrogen compounds, aromatic sulfur compounds, phenolic compounds and other aromatic oxygen compounds, and their alkyl derivatives.	302-683-3	94114-48-4	Carc. 1B
clothianidin (ISO); 3-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-1-nitroguanidine	433-460-1	210880-92-5	Acute Tox. 4
Clostridium tetani	-	-		B Bacteria and similar species
Clostridium spp.	-	-		B Bacteria and similar species
Clostridium perfringens	-	-		B Bacteria and similar species
Clostridium botulinum	-	-		B Bacteria and similar species
clorofene; chlorophene; 2-benzyl-4-chlorophenol	204-385-8	120-32-1	Carc. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1; Eye Dam. 1; STOT RE 2
clopyralid (ISO); 3,6-dichloropyridine-2-carboxylic acid	216-935-4	1702-17-6	Eye Dam. 1
Clonorchisviverrini	-	-		P Parasites
Clonorchis sinensis	-	-		P Parasites
clomazone (ISO); 2-(2-chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one	617-258-0	81777-89-1	Acute Tox. 4
clodinafop-propargyl (ISO)	600-662-6	105512-06-9	Acute Tox. 4; STOT RE 2; Skin Sens. 1
clethodim (ISO); (5RS)-2-{(1EZ)-1-[(2E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylthio)propyl]-3-hydroxycyclohex-2-en-1-one	619-396-7	99129-21-2	Acute Tox. 4; Skin Sens. 1
Clarified oils (petroleum), hydrodesulfurized catalytic cracked; Heavy Fuel oil [A complex combination of hydrocarbons obtained by treating catalytic cracked clarified oil with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350 °C (662 °F). This stream is likely to contain 5 wt. % or more of 4-to 6-membered condensed ring aromatic hydrocarbons.] A complex combination of hydrocarbons obtained by treating catalytic cracked clarified oil with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.	269-782-0	68333-26-6	Carc. 1B
Clarified oils (petroleum), catalytic cracked; Heavy Fuel oil [A complex combination of hydrocarbons produced as the residual fraction from distillation of the products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4-to 6-membered condensed ring aromatic hydrocarbons.] A complex combination of hydrocarbons produced as the residual fraction from distillation of the products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly greater than C20 and boiling above approximately 350°C (662°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.	265-064-6	64741-62-4	Carc. 1B
Cladophialophora bantiana	-	-		F Fungi
citric acid, nickel salt	245-119-0	22605-92-1	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
citric acid, ammonium nickel salt	242-161-1	18283-82-4	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
citric acid	201-069-1	77-92-9	Eye Irrit. 2; STOT SE 3
citral	226-394-6	5392-40-5	Skin Irrit. 2; Skin Sens. 1
cis-dichloroethylene	205-859-7	156-59-2	Flam. Liq. 2; Acute Tox. 4
cis-cyclohexane-1,2-dicarboxylicanhydride	236-086-3	13149-00-3	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1		yes
cis-2-methylcyclohexanol	231-187-9	7443-70-1	Acute Tox. 4
cis-1-amino-2,3-dihydro-1H-inden-2-ol	422-660-2	7480-35-5	Eye Dam. 1; Skin Sens. 1
cis-1-(3-chloropropyl)-2,6-dimethyl-piperidin hydrochloride PD 133602-2	417-430-3	63645-17-0	Acute Tox. 3; STOT RE 2; Skin Sens. 1
cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride	426-020-3	51229-78-8	Flam. Sol. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
cis-1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinamine	425-080-8	104860-26-6	Acute Tox. 4; STOT RE 2; Eye Dam. 1
cis-1,2,3,6-tetrahydrophthalicanhydride	213-308-7	935-79-5	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cis-1,2,3,6-tetrahydro-4-methylphthalic anhydride	216-906-6	1694-82-2	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
cinmethylin (ISO); exo-(±)-1-methyl-2-(2-methylbenzyloxy)-4-isopropyl-7-oxabicyclo(2.2.1)heptane ARGOLD; CINMETHYLIN; WL 95481	402-410-9	87818-31-3	Acute Tox. 4
cinidon ethyl (ISO); ethyl (Z)-2-chloro-3-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboximido)phenyl]acrylate	604-318-6	142891-20-1	Carc. 2; Skin Sens. 1
cinerin II; 3-(but-2-enyl)-2-methyl-4- oxocyclopent-2-enyl 2,2-dimethyl-3-(3-methoxy-2-methyl-3-oxoprop-1-enyl)cyclopropanecarboxylate	204-454-2	121-20-0	Acute Tox. 4
cinerin I; 3-(but-2-enyl)-2-methyl-4- oxocyclopent-2-enyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	246-948-0	25402-06-6	Acute Tox. 4
chymotrypsin	232-671-2	9004-07-3	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
chrysoidine; 4-(phenylazo)benzene-1,3-diamine	207-803-7	495-54-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2
chrysoidine-p-dodecylbenzenesulfonate; dodecylbenzenesulfonic acid, compound with 4-(phenylazo)benzene-1,3-diamine (1:1)	264-409-8	63681-54-9	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine sulfate; bis[4-(phenylazo)benzene-1,3-diamine] sulfate	282-432-1	84196-22-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine monohydrochloride; 4-phenylazophenylene-1,3-diamine monohydrochloride	208-545-8	532-82-1	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine monoacetate; 4-(phenylazo)benzene-1,3-diamine monoacetate	278-290-5	75660-25-2	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine dihydrochloride; 4-(phenylazo)benzene-1,3-diamine dihydrochloride	281-549-5	83968-67-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine compound with dibutylnaphthalene sulfonic acid; dibutylnaphthalenesulfonic acid, compound with 4-(phenylazo)benzene-1,3-diamine (1:1)	304-236-8	94247-67-3	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine C10-14-alkyl derivatives; benzenesulfonic acid, mono-C10-14-alkyl derivatives, compounds; with 4-(phenylazo)-1,3-benzenediamine	286-946-7	85407-90-5	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysoidine acetate; 4-(phenylazo)benzene-1,3-diamine acetate	279-116-0	79234-33-6	Muta. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
chrysene	205-923-4	218-01-9	Carc. 1B; Muta. 2		yes
chromyl dichloride; chromic oxychloride	239-056-8	14977-61-8	Ox. Liq. 1; Carc. 1B; Muta. 1B; Skin Corr. 1A; Skin Sens. 1
chromium (VI) trioxide	215-607-8	1333-82-0	Ox. Sol. 1; Carc. 1A; Muta. 1B; Repr. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1		yes
chromium (VI) compounds, with the exception of barium chromate and of compounds specified elsewhere in this Annex	-	-	Carc. 1B; Skin Sens. 1
Chromic acid	231-801-5	7738-94-5			yes
chlozolinate (ISO); ethyl (RS)-3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-oxazolidine-5-carboxylate	282-714-4	84332-86-5	Carc. 2
chlorthiophos (ISO) [isomeric reaction mass in which O-2,5-dichlorophenyl-4-methylthiophenyl O, O-diethyl phosphorothioate predominates]	244-663-6	21923-23-9	Acute Tox. 2; Acute Tox. 3
chlorthion O-(3-chloro-4-nitrophenyl) O, O-dimethyl phosphorothioate	207-902-5	500-28-7	Acute Tox. 4
chlorthiamid (ISO); 2,6-dichloro (thiobenzamide)	217-637-7	1918-13-4	Acute Tox. 4
chlorpyrifos-methyl (ISO) O, O-dimethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate	227-011-5	5598-13-0	Skin Sens. 1
chlorpyrifos (ISO); O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate	220-864-4	2921-88-2	Acute Tox. 3
chlorpropham (ISO); isopropyl 3-chlorocarbanilate	202-925-7	101-21-3	Carc. 2; STOT RE 2
chlorphonium chloride (ISO); tributyl (2,4-dichlorobenzyl) phosphonium chloride	204-105-4	115-78-6	Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
chloroxylenol	215-316-6	1321-23-9	Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
chlorotricyclohexylstannane	221-437-5	3091-32-5	Acute Tox. 4
chlorotoluron (ISO); 3-(3-chloro-p-tolyl)-1,1-dimethylurea	239-592-2	15545-48-9	Carc. 2; Repr. 2
chlorotoluene	246-698-2	25168-05-2	Acute Tox. 4
chlorothalonil (ISO); tetrachloroisophthalonitrile	217-588-1	1897-45-6	Carc. 2; Acute Tox. 2; STOT SE 3; Eye Dam. 1; Skin Sens. 1
chlorosulphonic acid	232-234-6	7790-94-5	Skin Corr. 1A; STOT SE 3
chloroprene (stabilised); 2-chlorobuta-1,3-diene (stabilised)	204-818-0	126-99-8	Flam. Liq. 2; Carc. 1B; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
chlorophenol	246-691-4	25167-80-0	Acute Tox. 4
chlorophacinone (ISO); 2-(2-(4-chlorophenyl)phenylacetyl)indan-1,3-dione	223-003-0	3691-35-8	Repr. 1B; Acute Tox. 1; STOT RE 1
chloronitroanilines with the exception of those specified elsewhere in this Annex show/hide Benzenamine, chloronitro- EC / List no: - \| CAS no: 41587-36-4 4-chloro-2-nitroaniline EC / List no: 201-925-4 \| CAS no: 89-63-4 N-chloro-2-nitroaniline EC / List no: - \| CAS no: 59483-60-2 Benzenamine, 3-chloro-5-nitro- EC / List no: - \| CAS no: 5344-44-5 Benzenamine, 2-chloro-3-nitro- EC / List no: - \| CAS no: 3970-41-0 2-chloro-5-nitroaniline EC / List no: 228-498-7 \| CAS no: 6283-25-6 Benzenamine, 4-chloro-N-nitro- EC / List no: - \| CAS no: 69732-97-4 4-chloro-3-nitroaniline EC / List no: 211-231-3 \| CAS no: 635-22-3 5-chloro-2-nitroaniline EC / List no: 216-661-5 \| CAS no: 1635-61-6 3-chloro-4-nitroaniline EC / List no: 642-644-0 \| CAS no: 825-41-2 2-chloro-4-nitroaniline EC / List no: 204-502-2 \| CAS no: 121-87-9 2-chloro-6-nitroaniline EC / List no: 212-204-9 \| CAS no: 769-11-9 3-chloro-2-nitroaniline EC / List no: 261-782-9 \| CAS no: 59483-54-4	-	-	Acute Tox. 2; Acute Tox. 1; STOT RE 2
chloromethane; methyl chloride	200-817-4	74-87-3	Flam. Gas 1; Press. Gas; Carc. 2; STOT RE 2
chloroform; trichloromethane	200-663-8	67-66-3	Carc. 2; Repr. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 1; Eye Irrit. 2; Skin Irrit. 2
chloroethane	200-830-5	75-00-3	Flam. Gas 1; Press. Gas; Carc. 2
chlorodinitrobenzene	247-109-1	25567-67-3	Acute Tox. 3; STOT RE 2
chlorocresol; 4-chloro-m-cresol; 4-chloro-3-methylphenol	200-431-6	59-50-7	Acute Tox. 4; Skin Corr. 1C; Eye Dam. 1; STOT SE 3; Skin Sens. 1B
chlorobenzilate (ISO); ethyl 2,2-di(4-chlorophenyl)-2-hydroxyacetate; ethyl 4,4'-dichlorobenzilate	208-110-2	510-15-6	Acute Tox. 4
chlorobenzene	203-628-5	108-90-7	Flam. Liq. 3; Acute Tox. 4; Skin Irrit. 2
chloroanilines (with exception of those specified elsewhere in this Annex)	-	-	Acute Tox. 3; STOT RE 2
chloroacetyl chloride	201-171-6	79-04-9	Acute Tox. 3; STOT RE 1; Skin Corr. 1A
chloroacetonitrile	203-467-0	107-14-2	Acute Tox. 3
chloroacetic acid	201-178-4	79-11-8	Acute Tox. 3; Skin Corr. 1B
chloroacetaldehyde	203-472-8	107-20-0	Carc. 2; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B
chloro-N, N-dimethylformiminium chloride SEL DE VILSMEIER-HAACK	425-970-6	3724-43-4	Repr. 1B; Acute Tox. 4; Skin Corr. 1A
chloro-1-ethylcyclohexyl carbonate	444-950-8	99464-83-2	Muta. 2; Skin Sens. 1
chloro(3-(3-chloro-4-fluorophenyl)propyl)dimethylsilane SILAN MCS	410-270-5	770722-46-8	Skin Corr. 1A
chlormethyl methyl ether; chlorodimethyl ether	203-480-1	107-30-2	Flam. Liq. 2; Carc. 1A; Acute Tox. 4

Prikazano 3.101 - 3.200 od 4.821 rezultata.

Export search results to:

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

RELEVANT LEGISLATION

Contact EUCLEF Helpdesk

Contact Helpdesk

Last updated 06 rujna 2024. Database contains 4821 unique substances/entries.

Footer Nav Items