EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.

Last updated 09 rujna 2024. Database contains 4821 unique substances/entries.

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Prikaz 3.401 - 3.500 od 4.821 rezultata.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU_BA Directive 2000/54/EC	EU REACH: List of SVHC
bis(8-hydroxyquinolinium) sulphate	205-137-1	134-31-6	Acute Tox. 4
bis(4-methylbenzoyl)peroxide INTEROX-PMBP-70W; INTEROX-PMPB-70W	407-950-9	895-85-2	Org. Perox. B
bis(4-hydroxy-N-methylanilinium) sulphate	200-237-1	55-55-0	Acute Tox. 4; STOT RE 2; Skin Sens. 1
bis(4-fluorophenyl)-methyl-(1,2,4-triazol-4-ylmethyl)silane hydrochloride U 9649	401-380-4	89066-61-5	Eye Irrit. 2
bis(4-dodecylphenyl)iodonium hexafluoroantimonate	404-420-9	71786-70-4	Skin Sens. 1
bis(4-(1,2-bis(ethoxycarbonyl)ethylamino)-3-methylcyclohexyl)methane DESMOPHEN VP-LS 2973 E; DESMOPHEN VP-LS 2975 E; DESMOPHEN VP-LS 2985 E	412-060-9	136210-32-7	Skin Sens. 1
bis(3-(trimethoxysilyl)propyl)amine	280-084-5	82985-35-1	Eye Dam. 1
bis(3,5-di-tert-butylsalicylato-O1,O2)zinc BONTRON E-84; E-84	403-360-0	42405-40-3	Flam. Sol. 1; Acute Tox. 4
bis(2-methoxyethyl) phthalate	204-212-6	117-82-8	Repr. 1B		yes
bis(2-methoxyethyl) ether	203-924-4	111-96-6	Flam. Liq. 3; Repr. 1B		yes
bis(2-ethylhexyl)-4,5-epoxycyclohexane-1,2-dicarboxylate	430-700-5	10138-36-0	Skin Sens. 1
bis(2-ethylhexyl) phthalate; di-(2-ethylhexyl) phthalate; DEHP	204-211-0	117-81-7	Repr. 1B		yes
bis(2-ethylhexyl) dithiodiacetate DI(2-ETHYLHEXYL)DITHIODIGLYKOLAT; DP 327	404-510-8	62268-47-7	Acute Tox. 4; Skin Sens. 1
bis(2-dimethylaminoethyl)(methyl)amine	221-201-1	3030-47-5	Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
bis(2-chloroethyl) ether	203-870-1	111-44-4	Carc. 2; Acute Tox. 2; Acute Tox. 1
bis(2-(2-methoxyethoxy)ethyl)ether; tetraglyme	205-594-7	143-24-8	Repr. 1B		yes
bis(2,6-dimethoxybenzoyl)-2,4,4-trimethylpentylphosphinoxide CGI 403	412-010-6	145052-34-2	Skin Sens. 1
bis(2,4,6-trinitrophenyl)amine; hexyl	205-037-8	131-73-7	Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
bis(2,4,4-trimethylpentyl)dithiophosphonic acid	420-160-9	107667-02-7	Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1B
bis(2,2,6,6-tetramethyl-4-piperidyl) succinate TINUVIN 780	402-940-0	62782-03-0	Eye Irrit. 2
bis(1-methylethyl)-dimethoxysilane EURENOR 5021; PSX 872	421-540-7	18230-61-0	Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
bis(1,2,3-trithiacyclohexyldimethylammonium) oxalate; thiocyclam-oxalate	250-859-2	31895-22-4	Acute Tox. 4
bis(1,1-dimethyl-2-propynyloxy)dimethylsilane PLR-22; XC95-A0638	414-960-7	53863-99-3	Acute Tox. 4
biphenyl; diphenyl	202-163-5	92-52-4	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
biphenyl-4-ylamine; xenylamine; 4-aminobiphenyl	202-177-1	92-67-1	Carc. 1A; Acute Tox. 4		yes
biphenyl-3,3', 4,4'-tetrayltetraamine; diaminobenzidine	202-110-6	91-95-2	Carc. 1B; Muta. 2
biphenyl-2-ylamine	201-990-9	90-41-5	Carc. 2; Acute Tox. 4
binapacryl (ISO); 2-sec-butyl-4,6-dinitrophenyl-3-methylcrotonate	207-612-9	485-31-4	Repr. 1B; Acute Tox. 4
bifenthrin (ISO); (2-methylbiphenyl-3-yl)methylrel-(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	617-373-6	82657-04-3	Carc. 2; Acute Tox. 3; Acute Tox. 2; STOT RE 1; Skin Sens. 1B
bifenazate (ISO); isopropyl 2-(4-methoxybiphenyl-3-yl)hydrazinecarboxylate	442-820-5	149877-41-8	STOT RE 2; Skin Sens. 1
Bhanja	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
Beta-hexabromocyclododecane	603-802-4	134237-51-7			yes
beryllium oxide	215-133-1	1304-56-9	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
beryllium compounds with the exception of aluminium beryllium silicates, and with those specified elsewhere in this Annex show/hide Beryllium hydroxide EC / List no: 236-368-6 \| CAS no: 13327-32-7 Beryllium acetylide EC / List no: 208-050-7 \| CAS no: 506-66-1 Silicic acid, beryllium salt EC / List no: 261-293-0 \| CAS no: 58500-38-2 Beryllium diammonium tetrafluoride EC / List no: 238-948-4 \| CAS no: 14874-86-3 Steel manufacture, chemicals This category includes the chemical substances which are manufactured as part of steel and alloy steels. The following list identifies those elements which may exist in steel or which may comprise compounds present in steel or alloy steels. Aluminum, beryllium, boron, calcium, carbon, cerium, chromium, cobalt, copper, hafnium, iron, lanthanum, lead, magnesium, manganese, molybdenum, nickel, niobium, nitrogen, oxygen, phosphorus, selenium, silicon, sulfur, tantalum, tin, titanium, tungsten, vanadium, yttrium, zinc, zirconium. EC / List no: 266-048-1 \| CAS no: 65997-19-5 Beryllium diboride EC / List no: 235-694-6 \| CAS no: 12536-51-5 Beryllium phosphide EC / List no: 261-137-1 \| CAS no: 58127-61-0 Nitric acid, beryllium salt, tetrahydrate EC / List no: 690-699-4 \| CAS no: 13510-48-0 Beryllium sulfate tetrahydrate EC / List no: 629-461-1 \| CAS no: 7787-56-6 Bis(pentane-2,4-dionato-O,O')beryllium EC / List no: 233-513-5 \| CAS no: 10210-64-7 Bertrandite (Be4(OH)2O(SiO3)2) EC / List no: 235-299-9 \| CAS no: 12161-82-9 Beryllium di(acetate) EC / List no: 208-850-6 \| CAS no: 543-81-7 Beryllium carbonate EC / List no: 236-030-8 \| CAS no: 13106-47-3 Beryllium, bis(carbonato(2-))dihydroxytri- EC / List no: - \| CAS no: 66104-24-3 Beryllium selenide EC / List no: 235-450-9 \| CAS no: 12232-25-6 Hexakis[μ-(acetato-O:O')]-μ4-oxotetraberyllium EC / List no: 242-785-4 \| CAS no: 19049-40-2 Beryllium telluride EC / List no: 235-451-4 \| CAS no: 12232-27-8 Beryllium chloride EC / List no: 232-116-4 \| CAS no: 7787-47-5 Beryllium hydrogen phosphate (1:1) EC / List no: - \| CAS no: 13598-15-7 Beryllium nitrate trihydrate EC / List no: - \| CAS no: 7787-55-5 Beryllium nitrate EC / List no: 237-062-5 \| CAS no: 13597-99-4 Beryllium dibromide EC / List no: 232-115-9 \| CAS no: 7787-46-4 Beryllium hexaboride EC / List no: 235-657-4 \| CAS no: 12429-94-6 Beryllium orthosilicate EC / List no: 239-251-8 \| CAS no: 15191-85-2 Disodium tetrafluoroberyllate EC / List no: 237-630-2 \| CAS no: 13871-27-7 Phosphoric acid, beryllium salt EC / List no: 252-356-3 \| CAS no: 35089-00-0 Beryllium oxyfluoride EC / List no: - \| CAS no: 63990-88-5 Triberyllium nitride EC / List no: 215-132-6 \| CAS no: 1304-54-7 Copper alloy, Cu 96, Be 2.2-2.8, Ni 1.1 (CDA 827) EC / List no: - \| CAS no: 11108-64-8 Diethylberyllium EC / List no: 208-823-9 \| CAS no: 542-63-2 Zinc beryllium silicate EC / List no: - \| CAS no: 39413-47-3 Beryllium diboride EC / List no: 235-443-0 \| CAS no: 12228-40-9 Phosphoric acid, beryllium salt (2:3) EC / List no: - \| CAS no: 13598-26-0 Aluminium alloy, Al,Be EC / List no: 603-236-8 \| CAS no: 12770-50-2 Beryllium diiodide EC / List no: 232-119-0 \| CAS no: 7787-53-3 Beryllium phosphide (BeP2) EC / List no: - \| CAS no: 1268721-56-7 Octadecanoic acid, beryllium salt EC / List no: - \| CAS no: 16687-38-0 Beryllium fluoride EC / List no: 232-118-5 \| CAS no: 7787-49-7 Beryllium sulphate EC / List no: 236-842-2 \| CAS no: 13510-49-1 Beryllium sulphide EC / List no: 237-064-6 \| CAS no: 13598-22-6 Beryllium zinc silicate EC / List no: 247-151-0 \| CAS no: 25638-88-4 Tetraberyllium boride EC / List no: 235-695-1 \| CAS no: 12536-52-6	-	-	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
beryllium	231-150-7	7440-41-7	Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
benzyltributylammonium 4-hydroxynaphthalene-1-sulphonate BONTRON P-51	402-240-5	102561-46-6	Acute Tox. 4
benzyldimethyloctadecylammonium 3-nitrobenzenesulfonate CA10	405-330-2	124088-59-1	Skin Irrit. 2; Eye Dam. 1
benzyldimethylamine	203-149-1	103-83-3	Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
benzylamine	202-854-1	100-46-9	Acute Tox. 4; Skin Corr. 1B
benzyl-N-(2-(2-methoxyphenoxy)ethyl)amine hydrochloride BM 96.0258.HCL	428-290-8	120606-08-8	Acute Tox. 4; Eye Dam. 1
benzyl-2-hydroxydodecyldi; methylammonium benzoate B 2049	402-610-6	113694-52-3	Skin Corr. 1B; Acute Tox. 4
benzyl(S)-2-[(2'-cyanobiphenyl-4-ylmethyl)pentanoylamino]-3-methylbutyrate	427-470-3	137864-22-3	Acute Tox. 4; Skin Sens. 1
benzyl violet 4B; α-[4-(4-dimethylamino-α-{4-[ethyl(3-sodiosulphonato benzyl)amino] phenyl}benzylidene)cyclohexa-2,5-dienylidene(ethyl)ammonio]toluene-3-sulphonate	216-901-9	1694-09-3	Carc. 2
benzyl salicylate	204-262-9	118-58-1	Skin Sens. 1B
benzyl chloroformate	207-925-0	501-53-1	Skin Corr. 1B
benzyl benzoate	204-402-9	120-51-4	Acute Tox. 4
benzyl alcohol	202-859-9	100-51-6	Acute Tox. 4
benzyl [hydroxy-(4-phenylbutyl)phosphinyl] acetate SQ 28,355; SQ 28355	416-050-5	87460-09-1	Eye Dam. 1
benzyl 2,4-dibromobutanoate B2,4DBB	420-710-8	23085-60-1	Repr. 2; Skin Irrit. 2; Skin Sens. 1
benzthiazuron (ISO); 1-benzothiazol-2-yl-3-methylurea	217-685-9	1929-88-0	Acute Tox. 4
benzoyl chloride	202-710-8	98-88-4	Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
benzovindiflupyr (ISO); N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	691-719-4	1072957-71-1	Acute Tox. 3
benzothiazole-2-thiol	205-736-8	149-30-4	Skin Sens. 1
benzophenone-3,3',4,4'-tetracarboxylic dianhydride; 4,4'-carbonyldi(phthalic anhydride)	219-348-1	2421-28-5	Eye Irrit. 2; STOT SE 3
benzonitrile	202-855-7	100-47-0	Acute Tox. 4
Benzol forerunnings (coal); Light Oil Redistillate, low boiling [The distillate from coke oven light oil having an approximate distillation range below 100 o C (212 °F). Composed primarily of C4 to C6 aliphatic hydrocarbons.] The distillate from coke oven light oil having an approximate distillation range below 100°C (212°F). Composed primarily of C4 to C6 aliphatic hydrocarbons.	266-023-5	65996-88-5	Carc. 1B; Muta. 1B
benzoic acid, N-tert-butyl-N'-(4-chlorobenzoyl)hydrazide	431-600-4	112226-61-6	Skin Sens. 1
benzoic acid	200-618-2	65-85-0	STOT RE 1; Skin Irrit. 2; Eye Dam. 1
benzo[rst]pentaphene	205-877-5	189-55-9	Carc. 1B; Muta. 2
benzo[k]fluoranthene	205-916-6	207-08-9	Carc. 1B		yes
benzo[j]fluoranthene	205-910-3	205-82-3	Carc. 1B
Benzo[ghi]perylene	205-883-8	191-24-2			yes
benzo[e]pyrene	205-892-7	192-97-2	Carc. 1B
benzo[a]pyrene; benzo[def]chrysene	200-028-5	50-32-8	Carc. 1B; Muta. 1B; Repr. 1B; Skin Sens. 1		yes
benzidine; 1,1'-biphenyl-4,4'-diamine; 4,4'-diaminobiphenyl; biphenyl-4,4'-ylenediamine	202-199-1	92-87-5	Carc. 1A; Acute Tox. 4
benzidine based azo dyes; 4,4'-diarylazobiphenyl dyes, with the exception of those specified elsewhere in this Annex	-	-	Carc. 1B
benzenesulfonic acid, 3,3'-(methylenebis((dihydroxyphenylene)azo)) bis-, potassium sodium salt; potassium sodium 3-[(E)-(6{3,4-dihydroxy-2-}(Z)-(3-sulfonatophenyl)diazenyl]benzyl}-2,3-dihydroxyphenyl)diazenyl]benzenesulfonate HWL-158	432-590-4	243869-48-9	Eye Irrit. 2
benzene-1,4-diamine dihydrochloride; p-phenylenediamine dihydrochloride	210-834-9	624-18-0	Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
benzene-1,2:4,5-tetracarboxylic dianhydride; benzene-1,2:4,5-tetracarboxylic dianhydride; pyromellitic dianhydride	201-898-9	89-32-7	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
benzene-1,2,4-tricarboxylic acid 1,2-anhydride; trimellitic anhydride	209-008-0	552-30-7	STOT SE 3; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1		yes
benzene	200-753-7	71-43-2	Flam. Liq. 2; Carc. 1A; Muta. 1B; STOT RE 1; Asp. Tox. 1; Eye Irrit. 2; Skin Irrit. 2
benzaldehyde	202-860-4	100-52-7	Acute Tox. 4
benz[e]acephenanthrylene	205-911-9	205-99-2	Carc. 1B
benz[a]anthracene	200-280-6	56-55-3	Carc. 1B		yes
bentazone (ISO);3-isopropyl-2,1,3-benzothiadiazine-4-one-2,2-dioxide	246-585-8	25057-89-0	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1
bensultap (ISO); 1,3-bis(phenylsulfonylthio)-2-(N,N-dimethylamino)propane	605-769-1	17606-31-4	Acute Tox. 4
bensulide (ISO); O, O-diisopropyl 2-phenylsulphonylaminoethyl phosphorodithioate	212-010-4	741-58-2	Acute Tox. 4
benquinox (ISO); p-benzoquinone 1-benzoylhydrazone 4-oxime	207-807-9	495-73-8	Acute Tox. 3; Acute Tox. 4
benomyl (ISO);methyl 1-(butylcarbamoyl)benzimidazol-2-ylcarbamate	241-775-7	17804-35-2	Muta. 1B; Repr. 1B; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
benfuracarb (ISO); ethyl N-[2,3-dihydro-2,2-dimethylbenzofuran-7-yloxycarbonyl(methyl)aminothio]-N-isopropyl-β-alaninate	617-356-3	82560-54-1	Repr. 2; Acute Tox. 3; Acute Tox. 4
bendiocarb (ISO); 2,2-dimethyl-1,3-benzodioxol-4-yl N-methylcarbamate	245-216-8	22781-23-3	Acute Tox. 3; Acute Tox. 2
benazolin (ISO); 4-chloro-2,3-dihydro-2-oxo-1,3-benzothiazol-3-ylacetic acid	223-297-0	3813-05-6	Eye Irrit. 2; Skin Irrit. 2
Belgrade	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
behenamidopropyl-dimethyl-(dihydroxypropyl) ammonium chloride LEXQUAT AMG-BEO (CONCENTRATE)	423-420-1	136920-10-0	Eye Dam. 1; Skin Sens. 1
Bebaru virus	-	-		V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans.
BBP; benzyl butyl phthalate e	201-622-7	85-68-7	Repr. 1B		yes
basic phenylmercury nitrate	620-403-0	8003-05-2	Acute Tox. 3; STOT RE 1; Skin Corr. 1B
Bartonella quintana	-	-		B Bacteria and similar species
Bartonella bacillifonnis	-	-		B Bacteria and similar species
Bartonella (Rochalinea) spp.	-	-		B Bacteria and similar species
barium sulphide	244-214-4	21109-95-5	Acute Tox. 4
barium salts, with the exception of barium sulphate, salts of 1-azo-2-hydroxynaphthalenyl aryl sulphonic acid, and of salts specified elsewhere in this Annex	-	-	Acute Tox. 4
barium polysulphides	256-814-3	50864-67-0	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
barium peroxide	215-128-4	1304-29-6	Ox. Sol. 2; Acute Tox. 4
barium perchlorate	236-710-4	13465-95-7	Ox. Sol. 1; Acute Tox. 4
barium chloride	233-788-1	10361-37-2	Acute Tox. 3; Acute Tox. 4
barium chlorate	236-760-7	13477-00-4	Ox. Sol. 1; Acute Tox. 4
barium carbonate	208-167-3	513-77-9	Acute Tox. 4
barium calcium cesium lead samarium strontium bromide chloride fluoride iodide europium doped	431-780-4	199876-46-5	Acute Tox. 4; STOT RE 2
barban (ISO); 4-chlorbut-2-ynyl N-(3-chlorophenyl)carbamate	202-930-4	101-27-9	Acute Tox. 4; Skin Sens. 1

Prikaz 3.401 - 3.500 od 4.821 rezultata.

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EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998

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Last updated 09 rujna 2024. Database contains 4821 unique substances/entries.

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