EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Last updated 12 rujna 2024. Database contains 4917 unique substances/entries.
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445-890-5
201290-01-9
Acute Tox. 4; Skin Sens. 1
Details
418-290-6
168612-06-4
Eye Irrit. 2; Skin Sens. 1
Details
DDPD
406-610-7
62478-82-4
Flam. Liq. 3; Acute Tox. 4; STOT RE 2; Skin Corr. 1A
Details
HOSTALUX VP 3481
401-410-6
10357-99-0
STOT RE 2; Skin Sens. 1
Details
B1; N,N-DIMETHYLANILINUM TETRAKIS(PENTAFLUOROPHENYL)BORATE; TÉTRAKIS(PENTAFLUOROPHÉNYL)BORATE DE N,N-DIMÉTHYLANILINIUM
422-050-6
118612-00-3
Carc. 2; Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
Details
F.H.D.A.
403-510-5
19247-05-3
Acute Tox. 3; STOT RE 2; Skin Sens. 1
Details
NYLOSTAB S-EED; NYSEED
419-710-0
42774-15-2
Acute Tox. 4; Eye Irrit. 2
Details
RED REN 363
419-500-9
171599-85-2
Eye Dam. 1; Skin Sens. 1
Details
210-338-2
613-35-4
Carc. 1B; Muta. 2; Acute Tox. 4
Details
QUESTAMIDE H
422-560-9
149591-38-8
Repr. 2; Eye Irrit. 2
Details
-
2810-74-4
Acute Tox. 4
Details
227-062-3
5625-90-1
Carc. 1B; Muta. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1; Eye Dam. 1
Details
LICHTSCHUTZMITTEL 1736
413-610-0
124172-53-8
Eye Irrit. 2
Details
PFMT 1848
410-060-3
130728-76-6
Muta. 2; Skin Sens. 1
Details
CHIMASSORB 119; LOWILITE 19
401-990-0
106990-43-6
Skin Sens. 1
Details
205-319-0
138-24-9
Acute Tox. 3
Details
431-530-4
1380226-29-8
Skin Corr. 1A; Skin Sens. 1
Details
205-149-7
134-62-3
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Details
202-088-8
91-66-7
Acute Tox. 3; STOT RE 2
Details
204-495-6
121-72-2
Acute Tox. 3; STOT RE 2
Details
210-199-8
609-72-3
Acute Tox. 3; STOT RE 2
Details
202-805-4
99-97-8
Carc. 1B; Acute Tox. 4; Acute Tox. 3; STOT RE 2
Details
204-493-5
121-69-7
Carc. 2; Acute Tox. 3
Details
220-623-3
2836-04-6
Acute Tox. 3
Details
200-316-0
57-14-7
Flam. Liq. 2; Carc. 1B; Acute Tox. 3; Skin Corr. 1B
Details
429-640-2
52870-46-9
Eye Irrit. 2
Details
PPX-HCL
417-950-0
65797-42-4
Acute Tox. 4
Details
423-840-3
14691-89-5
Acute Tox. 4
Details
247-161-5
25646-71-3
Acute Tox. 4; Skin Sens. 1
Details
UM-229
407-070-5
142859-67-4
Skin Sens. 1
Details
425-650-6
171887-03-9
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
Details
477-690-9
874819-71-3
Repr. 1B; STOT RE 2
Details
UC-129
403-790-9
108673-51-4
Skin Sens. 1
Details
811-438-4
1255734-28-1
Repr. 2; Acute Tox. 4; Skin Sens. 1B
Details
TSD-40
413-200-1
129604-78-0
Skin Sens. 1
Details
211-952-3
719-96-0
Skin Irrit. 2
Details
NOP; SURFADONE LP-100 SURFACTANT
403-700-8
2687-94-7
Skin Corr. 1B
Details
205-223-9
135-88-6
Carc. 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
BTAD
416-470-9
170292-97-4
Eye Irrit. 2
Details
430-360-8
84793-24-8
Eye Dam. 1; Skin Sens. 1
Details
DISPERSOL BLUE C-4G COLOUR; SUBSTANCE H87919
416-860-9
777891-21-1
Repr. 2; Skin Sens. 1
Details
DS 100
415-060-7
1379678-87-1
Eye Dam. 1; Skin Sens. 1
Details
423-530-8
152828-23-4
STOT RE 1; Acute Tox. 4
Details
BENZANILID-DISPERSE-INTERMEDIATE ZP 9955
411-590-8
70693-57-1
Skin Corr. 1B
Details
427-880-2
90357-53-2
STOT RE 2
Details
424-550-1
84245-12-5
Carc. 1B; Muta. 1B; Repr. 1B
Details
429-120-5
208535-04-0
Eye Dam. 1
Details
425-300-2
186450-73-7
Skin Sens. 1
Details
204-658-1
123-86-4
Flam. Liq. 3; STOT SE 3
Details
205-480-7
141-32-2
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Details
202-615-1
97-88-1
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Details
209-669-5
590-01-2
Flam. Liq. 3
Details
EP 389
407-730-2
104958-67-0
Eye Irrit. 2; Skin Sens. 1
Details
DISPERSOL YELLOW XF
407-970-8
75511-91-0
Skin Sens. 1
Details
203-700-6
109-74-0
Flam. Liq. 2; Acute Tox. 3
Details
200-652-8
67-43-6
Repr. 1B; Acute Tox. 4; STOT RE 2; Eye Irrit. 2
Details
PREVENTOL VP OC 3061
423-990-1
149118-66-1
Acute Tox. 4; Eye Dam. 1
Details
202-411-2
95-33-0
Skin Sens. 1
Details
DIMETHYLPAPAMIDOLAURDIMONIUM TOSYLATE
421-130-8
156679-41-3
Eye Dam. 1; Skin Sens. 1
Details
220-250-6
2687-91-4
Repr. 1B
Details
437-720-3
227085-51-0
Eye Dam. 1
Details
CATALYST 4017
407-780-5
4186-71-4
Acute Tox. 4
Details
203-135-5
103-69-5
Acute Tox. 3; STOT RE 2
Details
DTBA
401-980-6
-
Skin Irrit. 2; Skin Sens. 1
Details
203-777-6
110-54-3
Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; STOT SE 3
Details
N-HEXYLLITHIUM
404-950-0
21369-64-2
Water-react. 1; Pyr. Sol. 1; Skin Corr. 1A
Details
202-969-7
101-72-4
Acute Tox. 4; Skin Sens. 1
Details
817-852-1
1228284-64-7
Carc. 2; Repr. 2
Details
N-METHYL-4-(P-FORMYLSTYRYL)-PYRIDINIUM METHYLSULFATE; SBQ; SBQ-SALZ
418-240-3
74401-04-0
Skin Sens. 1
Details
211-795-0
696-44-6
Acute Tox. 3; STOT RE 2
Details
207-531-9
479-45-8
Expl. 1.1; Acute Tox. 3; STOT RE 2
Details
429-340-1
186295-11-4
Acute Tox. 4; Eye Dam. 1
Details
210-260-9
611-21-2
Acute Tox. 3; STOT RE 2
Details
210-769-6
623-08-5
Acute Tox. 3; STOT RE 2
Details
202-870-9
100-61-8
Acute Tox. 3; STOT RE 2
Details
424-460-0
283167-56-6
Acute Tox. 4; Skin Sens. 1
Details
204-624-6
123-39-7
Repr. 1B; Acute Tox. 4
Details
431-060-1
153719-38-1
Acute Tox. 4; Skin Sens. 1
Details
688-331-2
874967-67-6
Carc. 2
Details
426-150-0
121246-28-4
Skin Sens. 1
Details
218-130-3
2051-79-8
Acute Tox. 3; Eye Irrit. 2; Skin Sens. 1
Details
205-547-0
142-59-6
Acute Tox. 4; STOT SE 3; Skin Sens. 1
Details
-
-
P Parasites
Details
206-098-3
300-76-5
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Details
The residue remaining from the distillation of recovered naphtha. Composed primarily of naphthalene and condensation products of indene and styrene.
292-636-2
90641-12-6
Carc. 1B; Muta. 1B
Details
Fraction of the distillate obtained by hydrocracking of coal extract or solution produced by the liquid solvent extraction or supercritical gas extraction processes and boiling in the range of approximately 30°C to 180°C (86°F to 356°F). Composed primarily of aromatic, hydrogenated aromatic and naphthenic compounds, their alkyl derivatives and alkanes with carbon numbers predominantly in the range of C4 to C9. Nitrogen, sulfur and oxygen-containing aromatic and hydrogenated aromatic compounds are also present.
302-690-1
94114-54-2
Carc. 1B; Muta. 1B
Details
A complex combination of hydrocarbons obtained by subjecting a petroleum naphtha to a sweetening process to convert mercaptans or to remove acidic impurities. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately minus 10°C to 230°C (14°F to 446°F).
265-089-2
64741-87-3
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
271-635-0
68603-08-7
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by the distillation of products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly in the range of C1 through C5.
272-185-8
68783-09-5
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons obtained from the catalytic dewaxing of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 35°C to 230°C (95°F to 446°F).
265-170-2
64742-66-1
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by fractionation from catalytically reformed hydrodesulfurized naphtha. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C7 to C13 and boiling in the range of approximately 98°C to 218°C (208°F to 424°F).
285-508-2
85116-57-0
Asp. Tox. 1
Details
A complex combination of hydrocarbons remaining after removal of aromatic compounds from catalytic reformed light naphtha in a selective absorption process. It consists predominantly of paraffinic and cyclic compounds having carbon numbers predominantly in the range of C5 to C8 and boiling in the range of approximately 66°C to 121°C (151°F to 250°F).
285-510-3
85116-59-2
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by the distillation of products from a catalytic reforming process. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately 30°C to 220°C (90°F to 430°F). It contains a relatively large proportion of aromatic and branched chain hydrocarbons. This stream may contain 10 vol. % or more benzene.
273-271-8
68955-35-1
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C12 and boiling in the range of approximately 65°C to 230°C (149°F to 446°F).
265-122-0
64742-22-9
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
265-123-6
64742-23-0
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons resulting from treatment of full-range straight-run naphtha with natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately -20°C to 220°C (-4°F to 429°F).
271-262-3
68527-21-9
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons resulting from treatment of light straight-run naphtha with a natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C10 and boiling in the range of approximately 93°C to 180°C (200°F to 356°F).
271-263-9
68527-22-0
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by the distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 with some butanes and boiling in the range of approximately 35°C to 200°C (95°F to 428°F).
271-267-0
68527-27-5
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
265-066-7
64741-64-6
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details
A complex combination of hydrocarbons produced by the distillation of products from a fluid coker. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C4 through C15 and boiling in the range of approximately 43°C to 250°C(110°F-500°F).
270-991-4
68513-02-0
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details

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