EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Last updated 11 listopada 2024. Database contains 4918 unique substances/entries.
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235-183-8
12124-97-9
Repr. 1B; Lact.; STOT SE 3; STOT RE 1; Eye Irrit. 2
Details
235-180-1
12122-67-7
STOT SE 3; Skin Sens. 1
Details
235-113-6
12069-69-1
Acute Tox. 4; Eye Irrit. 2
Details
235-103-1
12068-61-0
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
235-067-7
12065-90-6
R Toxic for reproduction (article 57c)
Details
235-038-9
12060-00-3
R Toxic for reproduction (article 57c)
Details
235-033-1
12059-14-2
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
235-023-7
12057-74-8
Water-react. 1; Acute Tox. 2; Acute Tox. 3; Acute Tox. 1
Details
235-008-5
12054-48-7
Carc. 1A; Repr. 1B; Muta. 2; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
234-853-7
12036-76-9
R Toxic for reproduction (article 57c)
Details
234-829-6
12035-72-2
Carc. 1A; Muta. 2; Acute Tox. 3; STOT RE 1; Skin Sens. 1
Details
234-828-0
12035-64-2
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-825-4
12035-39-1
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-824-9
12035-38-0
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-823-3
12035-36-8
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-541-0
12008-41-2
Repr. 1B
R Toxic for reproduction (article 57c)
Details
234-495-1
12007-02-2
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-494-6
12007-01-1
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-493-0
12007-00-0
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-454-8
12004-35-2
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Repr. 1B; STOT SE 3; Eye Dam. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
R Toxic for reproduction (article 57c)
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
R Toxic for reproduction (article 57c)
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
R Toxic for reproduction (article 57c)
Details
234-390-0
11138-47-9;12040-72-1;37244-98-7
Ox. Sol. 3; Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
234-363-3
11120-22-2
R Toxic for reproduction (article 57c)
Details
234-349-7
11113-75-0
Carc. 1A; Muta. 2; STOT RE 1; Skin Sens. 1
Details
234-348-1
11113-74-9
Carc. 1A; Repr. 1B; Muta. 2; STOT RE 1; Acute Tox. 4; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
234-343-4
11113-50-1
Repr. 1B
R Toxic for reproduction (article 57c)
Details
234-323-5
11099-02-8
Carc. 1A; STOT RE 1; Skin Sens. 1
Details
234-290-7
11070-44-3
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
Details
234-284-4
11066-49-2
ENDE Endocrine disrupting properties (Article 57(f) - environment)
Details
234-239-9
11005-63-3
Acute Tox. 3; STOT RE 2
Details
234-232-0
10605-21-7
Muta. 1B; Repr. 1B; Skin Sens. 1
Details
234-190-3
10588-01-9
Ox. Sol. 2; Carc. 1B; Muta. 1B; Repr. 1B; Acute Tox. 2; Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
C Carcinogenic (article 57a)
M Mutagen (article 57b)
R Toxic for reproduction (article 57c)
Details
234-129-0
10545-99-0
Skin Corr. 1B; STOT SE 3
Details
234-126-4
10544-72-6
Press. Gas; Ox. Gas 1; Acute Tox. 2; Skin Corr. 1B
Details
233-940-7
10453-86-8
Acute Tox. 4
Details
233-844-5
10381-36-9
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Details
233-788-1
10361-37-2
Acute Tox. 3; Acute Tox. 4
Details
233-710-6
10325-94-7
Carc. 1B; Muta. 1B; Acute Tox. 4; STOT RE 1
Details
233-689-3
10311-84-9
Acute Tox. 2; Acute Tox. 3
Details
233-663-1
10294-56-1
Acute Tox. 4; Skin Corr. 1A
Details
233-658-4
10294-34-5
Press. Gas; Acute Tox. 2; Skin Corr. 1B
Details
233-657-9
10294-33-4
Acute Tox. 2; Skin Corr. 1A
Details
233-606-0
10265-92-6
Acute Tox. 2; Acute Tox. 3
Details
233-539-7
10222-01-2
Acute Tox. 2; Acute Tox. 3; STOT RE 1; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
Details
233-402-1
10141-05-6
Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
C Carcinogenic (article 57a)
R Toxic for reproduction (article 57c)
Details
233-334-2
10124-43-3
Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 4; Resp. Sens. 1; Skin Sens. 1
C Carcinogenic (article 57a)
R Toxic for reproduction (article 57c)
Details
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Sulfuric acid, cadmium salt, hydrate (3:3:8) EC / List no: 616-572-5 | CAS no: 7790-84-3
Sulfuric acid, cadmium salt (1:1), hydrate EC / List no: 626-360-4 | CAS no: 15244-35-6
233-331-6
10124-36-4;31119-53-6
Carc. 1B; Muta. 1B; Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
C Carcinogenic (article 57a)
M Mutagen (article 57b)
R Toxic for reproduction (article 57c)
HH2 Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
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Sulfuric acid, cadmium salt (1:1), hydrate EC / List no: 626-360-4 | CAS no: 15244-35-6
Sulfuric acid, cadmium salt, hydrate (3:3:8) EC / List no: 616-572-5 | CAS no: 7790-84-3
233-331-6
10124-36-4;31119-53-6
C Carcinogenic (article 57a)
M Mutagen (article 57b)
R Toxic for reproduction (article 57c)
HH2 Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
233-307-5
10112-91-1
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
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cadmium chloride (CdCl2), hydrate (2:5) EC / List no: 640-998-0 | CAS no: 7790-78-5
233-296-7
10108-64-2
Carc. 1B; Muta. 1B; Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
C Carcinogenic (article 57a)
M Mutagen (article 57b)
R Toxic for reproduction (article 57c)
HH2 Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
233-272-6
10102-44-0
Press. Gas; Ox. Gas 1; Acute Tox. 2; Skin Corr. 1B
Details
233-267-9
10102-18-8
Acute Tox. 2; Acute Tox. 3; Skin Sens. 1
Details
233-263-7
10101-96-9
Carc. 1A; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Details
233-245-9
10099-74-8
R Toxic for reproduction (article 57c)
Details
233-195-8
10061-01-5
Flam. Liq. 3; Acute Tox. 3; Acute Tox. 4; Asp. Tox. 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Details
233-162-8
10049-04-4
Acute Tox. 3; Skin Corr. 1B
Details
233-162-8
10049-04-4
Press. Gas; Ox. Gas 1; Acute Tox. 2; Skin Corr. 1B
Details
233-154-4
10046-00-1
Expl. 1.1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
233-140-8
10043-52-4
Eye Irrit. 2
Details
233-139-2
10043-35-3
Repr. 1B
R Toxic for reproduction (article 57c)
Details
233-118-8
10039-54-0
Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
233-113-0
10035-10-6
Press. Gas; Skin Corr. 1A; STOT SE 3
Details
233-113-0
10035-10-6
Skin Corr. 1B; STOT SE 3
Details
233-109-9
10034-85-2
Skin Corr. 1B
Details
233-109-9
10034-85-2
Press. Gas; Skin Corr. 1A
Details
233-071-3
10028-18-9
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Details
233-060-3
10026-13-8
Acute Tox. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B
Details
233-054-0
10026-04-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
233-051-4
10026-00-3
Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
Details
233-050-9
10025-99-7
Acute Tox. 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
Details
233-047-2
10025-91-9
Skin Corr. 1B
Details
233-046-7
10025-87-3
Acute Tox. 2; STOT RE 1; Acute Tox. 4; Skin Corr. 1A
Details
233-042-5
10025-78-2
Flam. Liq. 1; Water-react. 1; Acute Tox. 3; Acute Tox. 4; Skin Corr. 1A; Eye Dam. 1
Details
233-036-2
10025-67-9
Acute Tox. 3; Acute Tox. 4; Skin Corr. 1A
Details
233-002-7
10007-85-9
Eye Irrit. 2
Details
233-000-6
10004-44-1
Repr. 2; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
Details
232-989-1
9080-17-5
Skin Corr. 1B
Details
232-966-6
9068-59-1
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-752-2
9014-01-1
STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1
Details
232-734-4
9012-54-8
Resp. Sens. 1
Details
232-671-2
9004-07-3
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-650-8
9002-07-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-645-0
9001-98-3
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-629-3
9001-75-6
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-627-2
9001-73-4
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-599-1
9001-33-6
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-589-7
9001-22-3
Resp. Sens. 1
Details
232-572-4
9001-00-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
232-565-6
9000-90-2
Resp. Sens. 1
Details
A colorless, refined petroleum distillate that is free from rancid or objectionable odors and that boils in a range of approximately 148.8°C to 204.4°C (300°F to 400°F).
232-489-3
8052-41-3
Carc. 1B; Muta. 1B; STOT RE 1; Asp. Tox. 1
Details
A complex combination derived from tall oil. Composed primarily of tricyclic monocarboxylic acids, mainly abietic and dehydroabietic acids. Includes tall-oil rosin stabilized by catalytic disproportionation.
232-484-6
8052-10-6
Skin Sens. 1
Details
A complex combination derived from wood, especially pine wood. Composed primarily of resin acids and modified resin acids such as dimers and decarboxylated resin acids. Includes rosin stabilized by catalytic disproportionation.
232-475-7
8050-09-7
Skin Sens. 1
Details
A complex combination of hydrocarbons obtained by the fractional distillation of petroleum. This fraction boils in a range of approximately 20°C to 135°C (58°F to 275°F).
232-453-7
8032-32-4
Carc. 1B; Muta. 1B; Asp. Tox. 1
Details

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