EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

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Last updated 20 rujna 2024. Database contains 4917 unique substances/entries.
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Stranica 30 od 50
100 Broj stavki po stranici
Prikazano 2.901 - 3.000 od 4.917 rezultata.
Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU REACH: List of SVHC
EU_BA Directive 2000/54/EC
 
titanium tetrachloride
231-441-9
7550-45-0
Skin Corr. 1B
Details
mercury dichloride; mercuric chloride
231-299-8
7487-94-7
Muta. 2; Repr. 2; Acute Tox. 2; STOT RE 1; Skin Corr. 1B
Details
aluminium chloride, anhydrous
231-208-1
7446-70-0
Skin Corr. 1B
Details
trilead bis(orthophosphate)
231-205-5
7446-27-7
Repr. 1A; STOT RE 2
Details
dithallium sulphate; thallic sulphate
231-201-3
7446-18-6
Acute Tox. 2; STOT RE 1; Skin Irrit. 2
Details
sulphur dioxide
231-195-2
7446-09-5
Press. Gas; Acute Tox. 3; STOT SE 1; Skin Corr. 1B
Details
tellurium dioxide
231-193-1
7446-07-3
Repr. 1B; Lact.
Details
cis-2-methylcyclohexanol
231-187-9
7443-70-1
Acute Tox. 4
Details
trans-2-methylcyclohexanol
231-186-3
7443-52-9
Acute Tox. 4
Details
calcium
231-179-5
7440-70-2
Water-react. 2
Details
zirconium powder (pyrophoric);zirconium powder, dry (non pyrophoric)
231-176-9
7440-67-7
Water-react. 1; Pyr. Sol. 1
Details
zirconium powder (pyrophoric);zirconium powder, dry (non pyrophoric)
231-176-9
7440-67-7
Self-heat. 1
Details
zinc powder — zinc dust (pyrophoric)
231-175-3
7440-66-6
Water-react. 1; Pyr. Sol. 1
Details
uranium
231-170-6
7440-61-1
Acute Tox. 2; STOT RE 2
Details
cobalt
231-158-0
7440-48-4
Carc. 1B; Muta. 2; Repr. 1B; Resp. Sens. 1; Skin Sens. 1
Details
Cadmium;cadmium (non-pyrophoric);cadmium (pyrophoric)
231-152-8
7440-43-9
C Carcinogenic (article 57a)
HH2 Specific target organ toxicity after repeated exposure (Article 57(f) - human health)
Details
Cadmium;cadmium (non-pyrophoric);cadmium (pyrophoric)
231-152-8
7440-43-9
Pyr. Sol. 1; Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 2; STOT RE 1
Details
Cadmium;cadmium (non-pyrophoric);cadmium (pyrophoric)
231-152-8
7440-43-9
Carc. 1B; Muta. 2; Repr. 2; Acute Tox. 2; STOT RE 1
Details
beryllium
231-150-7
7440-41-7
Carc. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Details
arsenic
231-148-6
7440-38-2
Acute Tox. 3
Details
thallium
231-138-1
7440-28-0
Acute Tox. 2; STOT RE 2
Details
sodium
231-132-9
7440-23-5
Water-react. 1; Skin Corr. 1B
Details
potassium
231-119-8
7440-09-7
Water-react. 1; Skin Corr. 1B
Details
nickel;nickel powder [particle diameter < 1mm]
231-111-4
7440-02-0
Carc. 2; STOT RE 1; Skin Sens. 1
Details
nickel;nickel powder [particle diameter < 1mm]
231-111-4
7440-02-0
Carc. 2; STOT RE 1; Skin Sens. 1
Details
mercury
231-106-7
7439-97-6
Repr. 1B; Acute Tox. 2; STOT RE 1
Details
magnesium powder (pyrophoric);magnesium, powder or turnings
231-104-6
7439-95-4
Water-react. 1; Pyr. Sol. 1
Details
magnesium powder (pyrophoric);magnesium, powder or turnings
231-104-6
7439-95-4
Flam. Sol. 1; Water-react. 2; Self-heat. 1
Details
lithium
231-102-5
7439-93-2
Water-react. 1; Skin Corr. 1B
Details
Lead;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
Repr. 1A; Lact.
Details
Lead;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
R Toxic for reproduction (article 57c)
Details
Lead;lead massive: [particle diameter ≥ 1 mm];lead powder [particle diameter < 1 mm]
231-100-4
7439-92-1
Repr. 1A; Lact.
Details
aluminium powder (pyrophoric);aluminium powder (stabilised)
231-072-3
7429-90-5
Water-react. 2; Flam. Sol. 1
Details
aluminium powder (pyrophoric);aluminium powder (stabilised)
231-072-3
7429-90-5
Water-react. 2; Pyr. Sol. 1
Details
2-ethylhexyl-2-ethylhexanoate
231-057-1
7425-14-1
Repr. 2
Details
2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol
230-770-5
7311-27-5
ENDE Endocrine disrupting properties (Article 57(f) - environment)
Details
tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one; dimethyl propyleneurea
230-625-6
7226-23-5
Repr. 2; Acute Tox. 4; Eye Dam. 1
Details
didecyldimethylammonium chloride
230-525-2
7173-51-5
Acute Tox. 4; Skin Corr. 1B
Details
ethyl 2-cyanoacrylate
230-391-5
7085-85-0
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
butyltricyclohexylstannane
230-358-5
7067-44-9
Acute Tox. 4
Details
dioxacarb (ISO); 2-(1,3-dioxolan-2-yl)phenyl N-methylcarbamate
230-253-4
6988-21-2
Acute Tox. 3
Details
monocrotophos (ISO); dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate
230-042-7
6923-22-4
Muta. 2; Acute Tox. 2; Acute Tox. 3
Details
trans-1-methyl-4-(1-methylvinyl)cyclohexene
229-977-3
6876-12-6
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
Details
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)
229-962-1
6864-37-5
Acute Tox. 3; Acute Tox. 4; Skin Corr. 1A
Details
disodium metasilicate
229-912-9
6834-92-0
Skin Corr. 1B; STOT SE 3
Details
carbadox (INN);methyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide; 2-(methoxycarbonylhydrazonomethyl) quinoxaline 1,4-dioxide
229-879-0
6804-07-5
Flam. Sol. 1; Carc. 1B; Acute Tox. 4
Details
α,α-Bis[4-(dimethylamino)phenyl]-4 (phenylamino)naphthalene-1-methanol; C.I. Solvent Blue 4
229-851-8
6786-83-0
C Carcinogenic (article 57a)
Details
l-carvone; (5R)-2-methyl-5- (prop-1-en-2-yl)cyclohex-2-en- 1-one
229-352-5
6485-40-1
Skin Sens. 1
Details
Lead dipicrate
229-335-2
6477-64-1
R Toxic for reproduction (article 57c)
Details
2-methyl-p-phenylenediamine sulphate
228-871-4
6369-59-1
Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
Details
1,1'-(1,1-Dimethyl-3-methylene-1,3-propanediyl)bisbenzene
228-846-8
6362-80-7
VPVB very Persistent and very Bioaccumulative (article 57e)
Details
methylene dithiocyanate
228-652-3
6317-18-6
Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Skin Sens. 1
Details
1,1'-(1,3,3-Trimethylprop-1-ene-1,3-diyl)dibenzene
228-396-2
6258-73-7
VPVB very Persistent and very Bioaccumulative (article 57e)
Details
chlordimeform (ISO); N2-(4-chloro-o-tolyl)-N1,N1-dimethylformamidine
228-200-5
6164-98-3
Carc. 2; Acute Tox. 4
Details
Ammonium perfluoroheptanoate
228-098-2
6130-43-4
R Toxic for reproduction (article 57c)
PBT Persistent, Bioaccumulative and Toxic (article 57d)
VPVB very Persistent and very Bioaccumulative (article 57e)
HH Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
E Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Details
piperazine hydrochloride
228-042-7
6094-40-2
Repr. 2; Eye Irrit. 2; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
cyclopentane-1,2,3,4-tetracarboxylic dianhydride
227-964-7
6053-68-5
Eye Irrit. 2; STOT SE 3
Details
(S)-p-mentha-1,8-diene; l-limonene
227-815-6
5989-54-8
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1
Details
(R)-p-mentha-1,8-diene; d-limonene
227-813-5
5989-27-5
Flam. Liq. 3; Skin Irrit. 2; Skin Sens. 1B; Asp. Tox. 1
Details
(E)-2-methoxy-4-(prop-1-enyl)phenol
227-678-2
5932-68-3
Skin Sens. 1A
Details
terbuthylazine (ISO); N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine
227-637-9
5915-41-3
Acute Tox. 4; STOT RE 2
Details
(Z)-2-methoxy-4-(prop-1-enyl)phenol
227-633-7
5912-86-7
Skin Sens. 1A
Details
exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acrylate; isobornyl acrylate
227-561-6
5888-33-5
Skin Sens. 1A
Details
o-(p-isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate
227-534-9
5873-54-1
Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
coumatetralyl; 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin
227-424-0
5836-29-3
Repr. 1B; Acute Tox. 2; Acute Tox. 3; STOT RE 1
Details
azothoate (ISO); O-4-(4-chlorophenylazo)phenyl O,O-dimethyl phosphorothioate
227-419-3
5834-96-8
Acute Tox. 4
Details
brucine nitrate
227-317-9
5786-97-0
Acute Tox. 2
Details
drazoxolon (ISO); 4-(2-chlorophenylhydrazone)-3-methyl-5-isoxazolone
227-197-8
5707-69-7
Acute Tox. 3
Details
N,N'-methylenedimorpholine; N,N'-methylenebismorpholine [formaldehyde released from N,N'-methylenebismorpholine]; [MBM]
227-062-3
5625-90-1
Carc. 1B; Muta. 2; Acute Tox. 4; STOT RE 2; Skin Corr. 1B; Skin Sens. 1; Eye Dam. 1
Details
chlorpyrifos-methyl (ISO) O, O-dimethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate
227-011-5
5598-13-0
Skin Sens. 1
Details
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-908-9
5543-58-8
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
Details
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-907-3
5543-57-7
Repr. 1A; Acute Tox. 1; Acute Tox. 2; STOT RE 1
Details
hydroxylammonium chloride; hydroxylamine hydrochloride
226-798-2
5470-11-1
Met. Corr. 1; Carc. 2; Acute Tox. 4; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
citral
226-394-6
5392-40-5
Skin Irrit. 2; Skin Sens. 1
Details
1,2,3,6-tetrahydro-3-methylphthalic anhydride
226-247-6
5333-84-6
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
Details
sulphamidic acid; sulphamic acid; sulfamic acid
226-218-8
5329-14-6
Eye Irrit. 2; Skin Irrit. 2
Details
oxycarboxin (ISO); 2,3-dihydro-6-methyl-5-(N-phenylcarbamoyl)-1,4-oxothiine 4,4-dioxide
226-066-2
5259-88-1
Acute Tox. 4
Details
carboxin (ISO); 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide; 5,6-dihydro-2-methyl-1,4-oxathiine-3-carboxanilide
226-031-1
5234-68-4
STOT RE 2; Skin Sens. 1
Details
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride
226-009-1
5216-25-1
Carc. 1B; Repr. 2; STOT RE 1; Acute Tox. 4; STOT SE 3; Skin Irrit. 2
Details
3,7-dimethylocta-2,6-dienenitrile
225-918-0
5146-66-7
Muta. 1B
Details
3-butoxypropan-2-ol; propylene glycol monobutyl ether
225-878-4
5131-66-8
Eye Irrit. 2; Skin Irrit. 2
Details
ditalimfos (ISO); O, O-diethyl phthalimidophosphonothioate
225-875-8
5131-24-8
Skin Irrit. 2; Skin Sens. 1
Details
4,4'-methylenedi(cyclohexyl isocyanate); dicyclohexylmethane-4,4'-di-isocyanate
225-863-2
5124-30-1
Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
trisodium nitrilotriacetate
225-768-6
5064-31-3
Carc. 2; Acute Tox. 4; Eye Irrit. 2
Details
nickel(II) octanoate
225-656-7
4995-91-9
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1
Details
pentaerythritol tetraacrylate
225-644-1
4986-89-4
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
brucine sulphate
225-432-9
4845-99-2
Acute Tox. 2
Details
bromophos-ethyl (ISO); O-4-bromo-2,5-dichlorophenyl; O,O-diethyl phosphorothioate
225-399-0
4824-78-6
Acute Tox. 3; Acute Tox. 4
Details
2,2',2''-(hexahydro-1,3,5- triazine-1,3,5-triyl)triethanol;1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
225-208-0
4719-04-4
Acute Tox. 4; Skin Sens. 1
Details
morfamquat dichloride
225-062-8
4636-83-3
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
cadmium diformate; cadmiumformate
224-729-0
4464-23-7
Acute Tox. 3; Carc. 2; STOT RE 2
Details
nickel bis(2-ethylhexanoate)
224-699-9
4454-16-4
Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1
Details
sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethonolate; sodium dehydracetate
224-580-1
4418-26-2
Acute Tox. 4
Details
Isobutyl 4-hydroxybenzoate
224-208-8
4247-02-3
END Endocrine disrupting properties (Article 57(f) - human health)
Details
(S)-butan-2-ol
224-168-1
4221-99-2
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
Details
crotonaldehyde; 2-butenal
224-030-0
4170-30-3
Flam. Liq. 2; Muta. 2; Acute Tox. 2; Acute Tox. 3; STOT RE 2; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
Details
phosacetim (ISO); O,O-bis(4-chlorophenyl) N-acetimidoylphosphoramidothioate
223-874-7
4104-14-7
Acute Tox. 1; Acute Tox. 2
Details
3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate; isophorone di-isocyanate
223-861-6
4098-71-9
Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
4-isocyanatosulphonyltoluene; tosyl isocyanate
223-810-8
4083-64-1
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
Details
2,2'-oxydiethyl diacrylate; diethylene glycol diacrylate
223-791-6
4074-88-8
Acute Tox. 3; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
Details
Stranica 30 od 50
100 Broj stavki po stranici
Prikazano 2.901 - 3.000 od 4.917 rezultata.

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