EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Last updated 13 rujna 2024. Database contains 4917 unique substances/entries.
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204-402-9
120-51-4
Acute Tox. 4
Details
204-390-5
120-36-5
Acute Tox. 4; Skin Irrit. 2; Eye Dam. 1
Details
204-385-8
120-32-1
Carc. 2; Repr. 2; Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1; Eye Dam. 1; STOT RE 2
Details
204-371-1
120-12-7
PBT Persistent, Bioaccumulative and Toxic (article 57d)
Details
204-358-0
119-93-7
Carc. 1B; Acute Tox. 4
Details
204-355-4
119-90-4
Carc. 1B; Acute Tox. 4
Details
204-340-2
119-64-2
Eye Irrit. 2; Skin Irrit. 2
Details
204-337-6
119-61-9
Carc. 1B
Details
204-327-1
119-47-1
Repr. 1B
R Toxic for reproduction (article 57c)
Details
204-318-2
119-38-0
Acute Tox. 1; Acute Tox. 2
Details
204-317-7
119-36-8
Repr. 2; Acute Tox. 4; Skin Sens. 1B
Details
204-289-6
118-96-7
Expl. 1.1; Acute Tox. 3; STOT RE 2
Details
204-274-4
118-75-2
Eye Irrit. 2; Skin Irrit. 2
Details
204-273-9
118-74-1
Carc. 1B; STOT RE 1
Details
204-262-9
118-58-1
Skin Sens. 1B
Details
204-255-0
118-48-9
Eye Irrit. 2; Skin Sens. 1
Details
204-212-6
117-82-8
Repr. 1B
R Toxic for reproduction (article 57c)
Details
204-211-0
117-81-7
Repr. 1B
R Toxic for reproduction (article 57c)
ENDE Endocrine disrupting properties (Article 57(f) - environment)
END Endocrine disrupting properties (Article 57(f) - human health)
Details
204-210-5
117-80-6
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Details
204-195-5
117-52-2
Acute Tox. 3; STOT RE 1
Details
204-178-2
117-18-0
Acute Tox. 4; Skin Sens. 1
Details
204-171-4
117-08-8
Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1
Details
204-129-5
116-16-5
Acute Tox. 4
Details
204-127-4
116-15-4
Press. Gas; Acute Tox. 4; STOT SE 3
Details
204-126-9
116-14-3
Carc. 1B
Details
204-123-2
116-06-3
Acute Tox. 2; Acute Tox. 3
Details
204-121-1
116-01-8
Acute Tox. 4
Details
204-118-5
115-96-8
Carc. 2; Repr. 1B; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
204-114-3
115-90-2
Acute Tox. 1; Acute Tox. 2
Details
204-105-4
115-78-6
Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Details
204-082-0
115-32-2
Acute Tox. 4; Skin Irrit. 2; Skin Sens. 1
Details
204-081-5
115-31-1
Acute Tox. 4
Details
204-079-4
115-29-7
Acute Tox. 2; Acute Tox. 4
Details
204-077-3
115-27-5
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
204-076-8
115-26-4
Acute Tox. 1; Acute Tox. 2
Details
204-066-3
115-11-7
Flam. Gas 1; Press. Gas
Details
204-065-8
115-10-6
Flam. Gas 1; Press. Gas
Details
204-064-2
115-09-3
Carc. 2; Repr. 1A; Lact.; Acute Tox. 2; STOT RE 1
Details
204-062-1
115-07-1
Flam. Gas 1; Press. Gas
Details
204-043-8
114-26-1
Acute Tox. 3
Details
204-015-5
112-90-3
Acute Tox. 4; Asp. Tox. 1; STOT SE 3; STOT RE 2; Skin Corr. 1B
Details
203-988-3
112-59-4
Acute Tox. 4; Eye Dam. 1
Details
203-986-2
112-57-2
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
Details
203-985-7
112-56-1
Flam. Liq. 3; Acute Tox. 3
Details
203-977-3
112-49-2
Repr. 1B
R Toxic for reproduction (article 57c)
Details
203-961-6
112-34-5
Eye Irrit. 2
Details
203-951-1
112-25-4
Acute Tox. 4; Skin Corr. 1B
Details
203-950-6
112-24-3
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
Details
203-933-3
112-07-2
Acute Tox. 4
Details
203-931-2
112-05-0
Skin Irrit. 2; Eye Irrit. 2
Details
203-924-4
111-96-6
Flam. Liq. 3; Repr. 1B
R Toxic for reproduction (article 57c)
Details
203-921-8
111-92-2
Flam. Liq. 3; Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1
Details
203-906-6
111-77-3
Repr. 1B
Details
203-905-0
111-76-2
Acute Tox. 3; Acute Tox. 4; Skin Irrit. 2; Eye Irrit. 2
Details
203-892-1
111-65-9
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
Details
203-874-3
111-48-8
Eye Irrit. 2
Details
203-872-2
111-46-6
Acute Tox. 4
Details
203-870-1
111-44-4
Carc. 2; Acute Tox. 2; Acute Tox. 1
Details
203-869-6
111-43-3
Flam. Liq. 2; STOT SE 3
Details
203-868-0
111-42-2
Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
Details
203-867-5
111-41-1
Repr. 1B; Skin Corr. 1B; Skin Sens. 1
Details
203-865-4
111-40-0
Acute Tox. 4; Skin Corr. 1B; Skin Sens. 1
Details
203-856-5
111-30-8
Acute Tox. 2; Acute Tox. 3; STOT SE 3; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1A
RSP Respiratory sensitising properties (Article 57(f)) - human health)
Details
203-852-3
111-27-3
Acute Tox. 4
Details
203-839-2
111-15-9
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
203-838-7
111-14-8
Skin Corr. 1B
Details
203-820-9
110-97-4
Eye Irrit. 2
Details
203-815-1
110-91-8
Flam. Liq. 3; Acute Tox. 4; Skin Corr. 1B
Details
203-813-0
110-89-4
Flam. Liq. 2; Acute Tox. 3; Skin Corr. 1B
Details
203-812-5
110-88-3
Flam. Sol. 1; Repr. 2; STOT SE 3
Details
203-809-9
110-86-1
Flam. Liq. 2; Acute Tox. 4
Details
203-808-3
110-85-0
Repr. 2; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
Details
203-808-3
110-85-0
Repr. 2; Skin Corr. 1B; Resp. Sens. 1; Skin Sens. 1
Details
203-806-2
110-82-7
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
Details
203-804-1
110-80-5
Flam. Liq. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
203-798-0
110-74-7
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
Details
203-794-9
110-71-4
Flam. Liq. 2; Repr. 1B; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
203-792-8
110-69-0
Acute Tox. 3; Acute Tox. 4; Eye Irrit. 2
Details
203-788-6
110-65-6
Skin Corr. 1B; Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1
Details
203-777-6
110-54-3
Flam. Liq. 2; Repr. 2; Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; STOT SE 3
Details
203-772-9
110-49-6
Repr. 1B; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
203-770-8
110-46-3
Flam. Liq. 2; Acute Tox. 4
Details
203-769-2
110-45-2
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
Details
203-767-1
110-43-0
Flam. Liq. 3; Acute Tox. 4
Details
203-745-1
110-19-0
Flam. Liq. 2
Details
203-744-6
110-18-9
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1B
Details
203-743-0
110-17-8
Eye Irrit. 2
Details
203-742-5
110-16-7
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1
Details
203-737-8
110-12-3
Flam. Liq. 3; Acute Tox. 4
Details
203-733-6
110-05-4
Org. Perox. E; Flam. Liq. 2; Muta. 2
Details
203-728-9
110-01-0
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
Details
203-727-3
110-00-9
Flam. Liq. 1; Carc. 1B; Muta. 2; Acute Tox. 4; STOT RE 2; Skin Irrit. 2
C Carcinogenic (article 57a)
Details
203-726-8
109-99-9
Flam. Liq. 2; Carc. 2; Eye Irrit. 2; STOT SE 3
Details
203-722-6
109-95-5
Flam. Gas 1; Press. Gas; Acute Tox. 4
Details
203-721-0
109-94-4
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
Details
203-716-3
109-89-7
Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A
Details
203-713-7
109-86-4
Flam. Liq. 3; Repr. 1B; Acute Tox. 4
R Toxic for reproduction (article 57c)
Details
203-710-0
109-83-1
Acute Tox. 4; Skin Corr. 1B
Details
203-703-2
109-77-3
Acute Tox. 3
Details
203-700-6
109-74-0
Flam. Liq. 2; Acute Tox. 3
Details

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