EU-SAFETY_HEALTH_WORK-PREAMBLE

Safety and Health of Workers at Work Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of Directive 89/391/EEC, 29 June 1989, amended by Regulation 1137/2008/EC, 21 November 2008 (Table 3/Annex VI, CLP; Annex III, 2000/54/EC)

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Last updated 14 lipnja 2024. Database contains 4691 unique substances/entries.
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Proteinase, Bacillus neutral EC / List no: 278-547-1 | CAS no: 76774-43-1
Proteinase, Bacillus polymyxa neutral EC / List no: 255-914-4 | CAS no: 42613-33-2
Proteinase, serine EC / List no: 253-431-3 | CAS no: 37259-58-8
Proteinase, Aspergillus parasiticus neutral EC / List no: 254-418-5 | CAS no: 39335-09-6
Proteinase, Bacillus alcalophilus serine EC / List no: 306-090-0 | CAS no: 95979-76-3
Proteinase, Mucor aspartic EC / List no: 232-975-5 | CAS no: 9073-79-4
Proteinase, Bacillus subtilis EC / List no: 257-520-8 | CAS no: 51931-23-8
Proteinase, Aspergillus neutral EC / List no: 278-588-5 | CAS no: 77000-13-6
Proteinase, Agkistrodon serine EC / List no: 232-933-6 | CAS no: 9046-56-4
Proteinase, Serratia extracellular EC / List no: 253-457-5 | CAS no: 37312-62-2
Proteinase, oryzin EC / List no: 232-992-8 | CAS no: 9081-30-5
Proteinase, Tritirachium album serine EC / List no: 254-457-8 | CAS no: 39450-01-6
Proteinase, rhizopus acid EC / List no: 812-486-9 | CAS no: 9074-09-3
Proteinase, Bacillus licheniformis serine EC / List no: 279-361-3 | CAS no: 79986-26-8
Amylase, mixture with proteinase EC / List no: 685-079-5 | CAS no: 9001-11-0
Proteinase, Myxobacter AL-1, II EC / List no: 276-716-4 | CAS no: 72561-05-8
Amylase, mixed with proteinase, Bacillus cereus-fermented EC / List no: - | CAS no: 68909-35-3
Proteinase, microbial neutral EC / List no: 232-966-6 | CAS no: 9068-59-1
Proteinase, Bacillus subtilis metallo- EC / List no: 232-991-2 | CAS no: 9080-56-2
Proteinase, Staphylococcus aureus serine EC / List no: 259-611-8 | CAS no: 55354-32-0
Proteinase, Streptomyces griseus EC / List no: 232-909-5 | CAS no: 9036-06-0
Proteinase, Aspergillus oryzae neutral EC / List no: 232-990-7 | CAS no: 9080-55-1
Proteinase, serine (Tritirachium album) EC / List no: 686-165-5 | CAS no: 102925-54-2
Proteinase, Myxobacter α-lytic EC / List no: 253-448-6 | CAS no: 37288-76-9
Thrombin EC / List no: 232-648-7 | CAS no: 9002-04-4
Bacillus megaterium protease fermentation product EC / List no: - | CAS no: 68909-17-1
Proteinase, Bothrops atrox serine EC / List no: 232-918-4 | CAS no: 9039-61-6
Proteinase, microbial acid EC / List no: 256-862-5 | CAS no: 50936-52-2
Aspergillin M EC / List no: - | CAS no: 42615-60-1
Proteinase, Aspergillus alkaline EC / List no: 232-977-6 | CAS no: 9074-07-1
Proteinase, microbial alkaline EC / List no: 256-863-0 | CAS no: 50936-53-3
Bacteria, complex with amylase and proteinase EC / List no: - | CAS no: 68920-42-3
Proteinase, submandibular gland serine, A EC / List no: 279-893-6 | CAS no: 82047-85-6
Proteinase, Aspergillus niger neutral EC / List no: 254-422-7 | CAS no: 39346-39-9
Proteinase, pancreatic EC / List no: 232-626-7 | CAS no: 9001-72-3
Proteinase, bacterial E 30 serine EC / List no: - | CAS no: 39369-34-1
Proteinase, Bacillus alkaline EC / List no: 232-972-9 | CAS no: 9073-77-2
Proteinase, Bacillus subtilis, sutilain EC / List no: 235-390-3 | CAS no: 12211-28-8
Proteinase, Aspergillus melleus, semialkaline EC / List no: - | CAS no: 76106-83-7
Proteinase, Aspergillus acid EC / List no: 232-796-2 | CAS no: 9025-49-4
Myxobacteralphalyticproteinase EC / List no: - | CAS no: 12585-31-8
Proteinase, Bacillus subtilis serine EC / List no: 266-557-9 | CAS no: 67051-83-6
Proteinase, Endothia aspartic EC / List no: 253-395-9 | CAS no: 37205-60-0
Proteinase, aspartic EC / List no: 278-856-1 | CAS no: 78169-47-8
934-013-6
39450-01-6
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
822-682-6
1417782-03-6
Skin Sens. 1
817-852-1
1228284-64-7
Carc. 2; Repr. 2
811-718-6
86347-14-0
Acute Tox. 2; STOT SE 3; STOT SE 1; STOT RE 1
811-438-4
1255734-28-1
Repr. 2; Acute Tox. 4; Skin Sens. 1B
807-366-8
946578-00-3
Acute Tox. 4
804-373-8
951659-40-8
Acute Tox. 4; STOT RE 2
701-454-9
852403-68-0
Repr. 2; Lact.; STOT RE 2
701-271-4
-
Repr. 1B; Eye Irrit. 2
701-225-3
1101132-67-5
Carc. 2; Repr. 2; STOT RE 2
701-162-1
-
Repr. 1B
701-118-1
2156592-54-8
Repr. 1B; Eye Irrit. 2
701-107-1
1801269-77-1
Repr. 1B; Skin Corr. 1C; Eye Dam. 1
701-105-0
1801269-80-6
Repr. 1B; Skin Corr. 1C; Eye Dam. 1
695-989-4
2527-66-4
Acute Tox. 4; Acute Tox. 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1A
692-456-8
688046-61-9
Carc. 2
691-719-4
1072957-71-1
Acute Tox. 3
688-331-2
874967-67-6
Carc. 2
686-814-2
34363-01-4
Skin Irrit. 2; Skin Sens. 1
682-791-8
160430-64-8
Repr. 2; Acute Tox. 3
682-362-5
12527-76-3
Acute Tox. 4
680-302-2
95266-40-3
STOT RE 2; Skin Sens. 1B
680-227-5
71449-78-0
Skin Sens. 1
672-776-4
348635-87-0
Carc. 2; Eye Irrit. 2
642-974-5
400882-07-7
Carc. 2; Skin Sens. 1A
641-410-5
130066-44-3
Skin Sens. 1A
640-104-9
210555-94-5
Repr. 1B; Skin Corr. 1C; Eye Dam. 1
639-478-6
182635-99-0
Acute Tox. 4; Skin Corr. 1B
635-361-9
243973-20-8
Repr. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Sens. 1A
632-619-2
881685-58-1
Carc. 2; Repr. 1B; Skin Sens. 1B
630-448-8
62610-77-9
Acute Tox. 4; Skin Sens. 1
627-564-6
59-89-2
Carc. 1B; Muta. 2; STOT RE 1
622-370-8
1522-92-5
Carc. 1B; Muta. 2
620-440-2
12510-42-8
Carc. 1A
620-436-0
75736-33-3
Eye Irrit. 2
620-432-9
2122-19-2
Repr. 2; Acute Tox. 4
620-427-1
108173-90-6
Acute Tox. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
620-425-0
68049-83-2
Repr. 1B; STOT RE 2
620-422-4
4097-36-3
Acute Tox. 3
620-419-8
606-35-9
Expl. 1.1; Acute Tox. 4
620-411-4
123748-85-6
Acute Tox. 4; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1
620-410-9
4234-79-1
Acute Tox. 3; Acute Tox. 4
620-404-6
7572-29-4
Unst. Expl.; Carc. 2; STOT RE 2
620-403-0
8003-05-2
Acute Tox. 3; STOT RE 1; Skin Corr. 1B
620-400-4
12031-65-1
Carc. 1A; STOT RE 1; Skin Sens. 1
620-395-9
12737-30-3
Carc. 1A; STOT RE 1; Skin Sens. 1
620-379-1
3254-63-5
Acute Tox. 1; Acute Tox. 2
620-378-6
8065-48-3
Acute Tox. 1; Acute Tox. 2
620-377-0
13067-93-1
Acute Tox. 3; STOT SE 1; Acute Tox. 4; Eye Irrit. 2
620-370-2
2703-37-9
Acute Tox. 2; Acute Tox. 1
620-368-1
1031-47-6
Acute Tox. 1; Acute Tox. 2
620-365-5
9016-72-2
Acute Tox. 4; STOT RE 2; Skin Sens. 1
620-362-9
1918-18-9
Acute Tox. 4
620-359-2
8065-36-9
Acute Tox. 3
620-358-7
140-41-0
Carc. 2; Eye Irrit. 2; Skin Irrit. 2
620-041-3
907204-31-3
Lact.
619-823-7
494793-67-8
Carc. 2
619-396-7
99129-21-2
Acute Tox. 4; Skin Sens. 1
619-394-6
99105-77-8
Repr. 2; STOT RE 2; Skin Sens. 1A
619-377-3
98886-44-3
Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
619-290-0
97780-06-8
Eye Irrit. 2
619-020-1
94361-06-5
Repr. 1B; Acute Tox. 3; STOT RE 2
619-000-2
94125-34-5
Acute Tox. 4
618-392-2
9004-70-0
Expl. 1.1
618-075-9
87820-88-0
Carc. 2; Acute Tox. 4
618-004-1
87392-12-9
Skin Sens. 1
617-717-5
85509-19-9
Carc. 2; Repr. 1B; Acute Tox. 4
617-485-5
76714-88-0
Acute Tox. 4
617-373-6
82657-04-3
Carc. 2; Acute Tox. 3; Acute Tox. 2; STOT RE 1; Skin Sens. 1B
617-356-3
82560-54-1
Repr. 2; Acute Tox. 3; Acute Tox. 4
617-258-0
81777-89-1
Acute Tox. 4
617-243-9
81591-81-3
Acute Tox. 4
617-219-8
81334-34-1
Eye Irrit. 2
617-100-0
8051-02-3
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
616-995-5
8018-01-7
Carc. 2; Repr. 1B; STOT RE 2; Skin Sens. 1
616-932-1
8011-63-0
Acute Tox. 4; Eye Dam. 1
616-712-5
79622-59-6
Repr. 2; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1A
616-699-6
79538-32-2
Acute Tox. 1; Acute Tox. 2
616-669-2
79241-46-6
Repr. 2
616-510-7
7782-63-0
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2
616-477-9
7758-99-8
Acute Tox. 4; Eye Dam. 1
616-473-7
77536-68-6
Carc. 1A; STOT RE 1
616-472-1
77536-67-5
Carc. 1A; STOT RE 1
616-471-6
77536-66-4
Carc. 1A; STOT RE 1
616-379-6
76738-62-0
Repr. 2; Acute Tox. 4; Eye Irrit. 2
616-221-6
7541-49-3
Skin Irrit. 2
616-100-8
74499-35-7
Repr. 1B; Skin Corr. 1C; Eye Dam. 1
616-096-8
7446-19-7
Acute Tox. 4; Eye Dam. 1
615-339-5
71751-41-2
Repr. 2; Acute Tox. 2; Acute Tox. 1; STOT RE 1
615-273-7
71283-80-2
STOT RE 2; Skin Sens. 1
615-135-6
70630-17-0
Acute Tox. 4; Eye Dam. 1
614-708-8
68694-11-1
Repr. 1B; Acute Tox. 4; STOT RE 2; Skin Sens. 1
614-346-0
68157-60-8
Carc. 2
614-054-3
67375-30-8
Acute Tox. 3; STOT RE 2; STOT SE 3
613-953-8
66603-10-9
Flam. Sol. 1; Acute Tox. 3; STOT RE 2; Skin Irrit. 2; Eye Dam. 1
613-911-9
66230-04-4
Acute Tox. 3; STOT SE 1; STOT RE 2; Skin Sens. 1
613-108-3
62924-70-3
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
611-802-0
591-34-4
Flam. Liq. 3
611-595-7
57960-19-7
Skin Sens. 1; STOT SE 1; STOT RE 2
611-516-6
57369-32-1
Acute Tox. 4
611-341-5
55965-84-9
Acute Tox. 2; Acute Tox. 3; Skin Corr. 1C; Eye Dam. 1; Skin Sens. 1A
611-089-6
540-67-0
Flam. Gas 1; Press. Gas
610-700-3
51580-86-0
Acute Tox. 4; Eye Irrit. 2; STOT SE 3
610-007-6
422556-08-9
Skin Sens. 1
608-879-8
335104-84-2
Repr. 2; STOT RE 2; Skin Sens. 1
608-723-9
32289-58-0
Carc. 2; Acute Tox. 2; Acute Tox. 4; STOT RE 1; Eye Dam. 1; Skin Sens. 1B
608-595-4
312600-89-8
Flam. Sol. 1; Acute Tox. 4; STOT RE 2; Eye Dam. 1
608-192-3
283159-90-0
Carc. 2
608-042-7
27083-27-8
Carc. 2; Acute Tox. 2; Acute Tox. 4; STOT RE 1; Eye Dam. 1; Skin Sens. 1B
607-955-8
2655-14-3
Acute Tox. 4
607-329-4
24151-93-7
Acute Tox. 4
607-285-6
239110-15-7
Repr. 2
606-640-2
2079-00-7
Acute Tox. 2
606-566-0
20487-40-5
Flam. Liq. 2
606-523-6
203313-25-1
Repr. 2; STOT SE 3; Eye Irrit. 2; Skin Sens. 1A
606-373-1
197706-50-6
Skin Sens. 1
606-168-7
189278-12-4
Carc. 2
605-845-4
179101-81-6
Skin Sens. 1
605-769-1
17606-31-4
Acute Tox. 4
605-752-9
175217-20-6
STOT RE 2
605-747-1
175013-18-0
Acute Tox. 3; Skin Irrit. 2
605-683-4
173584-44-6
Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Sens. 1B
605-666-1
173159-57-4
Carc. 2
605-329-9
163515-14-8
Acute Tox. 4; Skin Sens. 1
605-127-0
158062-67-0
Acute Tox. 4
605-037-1
156052-68-5
Skin Sens. 1
605-015-1
155569-91-8
Acute Tox. 3; STOT SE 1; STOT RE 1; Eye Dam. 1
604-715-4
149979-41-9
Carc. 2; Repr. 2
604-712-8
149961-52-4
Carc. 2; Repr. 2; Acute Tox. 4
604-636-5
148477-71-8
Carc. 1B; Repr. 2; STOT RE 2; Skin Sens. 1B
604-430-5
144651-06-9
STOT RE 2
604-398-2
144171-61-9
Acute Tox. 3; Acute Tox. 4; STOT RE 1; Skin Sens. 1B
604-377-8
14371-10-9
Skin Sens. 1A
604-351-6
143390-89-0
Carc. 2
604-318-6
142891-20-1
Carc. 2; Skin Sens. 1
604-291-0
142469-14-5
Skin Sens. 1
604-290-5
142459-58-3
Acute Tox. 4; STOT RE 2; Skin Sens. 1
604-237-6
141517-21-7
Lact.; Skin Sens. 1
604-222-4
141112-29-0
Repr. 2
604-209-3
140923-17-7
Carc. 2
604-167-6
139968-49-3
Repr. 2; Lact.; STOT RE 2
604-105-8
139001-49-3
Carc. 2; Repr. 2; Skin Sens. 1
604-030-0
137641-05-5
STOT RE 2
603-921-1
135410-20-7
Repr. 2; Acute Tox. 3
603-902-8
13517-20-9
Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
603-902-8
13517-20-9
Repr. 1B; STOT SE 3; Eye Dam. 1
603-792-1
134098-61-6
Acute Tox. 3; Acute Tox. 2; Skin Sens. 1B
603-524-3
131860-33-8
Acute Tox. 3
603-520-1
131807-57-3
STOT RE 2
603-411-9
1303-96-4
Repr. 1B
603-404-0
130328-20-0
Repr. 2; Skin Irrit. 2; Eye Dam. 1
603-146-9
126535-15-7
Carc. 2
603-038-1
125225-28-7
Repr. 1B; Acute Tox. 4; STOT RE 2
603-031-3
125116-23-6
Repr. 2; Acute Tox. 4
602-997-3
124495-18-7
Skin Sens. 1
602-929-2
123333-53-9
Expl. 1.3
602-927-1
123312-89-0
Carc. 2; Repr. 2
602-894-3
12280-03-4
Repr. 1B
602-782-4
122453-73-0
Acute Tox. 3; Acute Tox. 4
601-810-2
12185-10-3
Pyr. Sol. 1; Acute Tox. 2; Skin Corr. 1A
601-808-1
12179-04-3
Repr. 1B
601-801-3
12172-73-5
Carc. 1A; STOT RE 1
601-785-8
121552-61-2
Skin Sens. 1
601-650-3
12001-29-5
Carc. 1A; STOT RE 1
601-649-8
12001-28-4
Carc. 1A; STOT RE 1
601-613-1
119446-68-3
Carc. 2; Acute Tox. 4; Eye Irrit. 2
601-585-0
119168-77-3
Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1B
601-505-4
118134-30-8
Repr. 2; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1
601-305-7
114311-32-9
Repr. 2
601-147-9
111988-49-9
Carc. 2; Repr. 1B; Acute Tox. 4; Acute Tox. 3; STOT SE 3
600-765-6
106700-29-2
Acute Tox. 4; Skin Sens. 1
600-662-6
105512-06-9
Acute Tox. 4; STOT RE 2; Skin Sens. 1
600-611-8
10486-00-7
Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
600-611-8
10486-00-7
Repr. 1B; STOT SE 3; Eye Dam. 1
600-594-7
104653-34-1
Repr. 1B; Acute Tox. 1; STOT RE 1
600-533-4
104206-82-8
Repr. 2; STOT RE 2
600-425-7
103361-09-7
Repr. 2
600-419-4
10332-33-9
Ox. Sol. 3; Repr. 1B; Acute Tox. 4; STOT SE 3; Eye Dam. 1
600-419-4
10332-33-9
Ox. Sol. 3; Repr. 1B; Acute Tox. 3; Acute Tox. 4; STOT SE 3; Eye Dam. 1
600-363-0
102851-06-9
Acute Tox. 4; Skin Irrit. 2
600-130-3
100784-20-1
Repr. 1B
500-033-5
25068-38-6
Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
479-100-5
577705-90-9
Repr. 1B
477-690-9
874819-71-3
Repr. 1B; STOT RE 2
451-440-9
586372-44-3
Eye Dam. 1
451-430-4
500717-36-2
Eye Dam. 1; Skin Sens. 1
450-010-8
-
Eye Dam. 1; Skin Sens. 1
N,N DIMETHYL DIETHOXY-2,2 ACETAMIDE
449-950-1
34640-92-1
Eye Irrit. 2
448-720-8
363138-44-7
Acute Tox. 4; Eye Dam. 1
AMINODARONE OXALATE; SR33580A
448-700-9
500791-70-8
STOT RE 2; Eye Dam. 1; Skin Sens. 1
447-920-2
897393-42-9
Repr. 2; Acute Tox. 4; Skin Corr. 1B; Eye Dam. 1
447-880-6
206565-89-1
Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1
447-860-7
144177-62-8
Repr. 2; STOT RE 2; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
PARADISAMIDE
446-190-2
406488-30-0
Acute Tox. 4; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1
445-990-9
376588-17-9
Skin Sens. 1
445-890-5
201290-01-9
Acute Tox. 4; Skin Sens. 1
DHP OPT
445-770-2
42031-28-7
Eye Dam. 1
445-750-3
839705-03-2
Acute Tox. 4; Eye Dam. 1; Skin Sens. 1
445-590-4
202197-26-0
Muta. 2; Acute Tox. 4; STOT RE 2
445-280-9
371921-40-3
Eye Dam. 1; Skin Sens. 1

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