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Diss Factsheets
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EC number: 272-945-9 | CAS number: 68921-53-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (3h) > 100 mg/L (nominal) for respiration inhibition of activated sludge (OECD 209)
Key value for chemical safety assessment
Additional information
Two studies investigating the toxicity of 2-Butenedioic acid (E)-, di-C18 -22-alkyl esters (CAS 68921-53-9) to aquatic microorganisms are available.
A static test was conducted according to OECD 209 and GLP using domestic activated sludge as inoculum (Hammer, 2013). Concentrations of 62.5, 125, 250, 500 and 1000 mg/L (nominal) were tested. The test substance was added in the required amounts according to the test concentrations directly to the test vessels. No respiration inhibition was observed up to the highest test substance concentration. The EC10 and EC50 are therefore > 1000 mg/L.
Another study was performed with 2-Butenedioic acid (E)-, di-C18 -22-alkyl esters (CAS 68921-53-9) but according to a German national guideline DIN 38412, part 27 (Kirch, 1995). In this study the inhibition of oxygen consumption for a 10000 mg/L filtered test item solution was measured after 30 min exposure time in Pseudomonas putida. As no inhibition was observed, the EC50 (30 min) is > 10000 mg/L. The test is reliable, but not appropriate enough for current regulatory demands and is therefore used as supporting information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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