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Diss Factsheets
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EC number: 700-066-7 | CAS number: 1472633-72-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol. Therefore, conducting an acute toxicity study on the reference substance is not feasible.
Key value for chemical safety assessment
Additional information
The reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol. Therefore, conducting a acute toxicity to aquatic invertebrates (daphnia) study on the reference substance is not feasible. If a study were conducted it would give a result representative of the hydrolysis products mentioned above.
The acute toxicity of the hydrolysis products, boric acid and glycerol has been assessed.
Boric acid
Study data on boric acid has been provided for the following endpoints:
- Toxicity to soil macroorganisms (see earthworm toxicity study)
- Sediment toxicity (see Toxicity test with the midge larva Chironomus riparius using spiked sediment.)
The results of these studies show boric acid to be of very low toxicity to soil and sediment invertebrates. This indicates that boric acid would also be of low toxicity to aquatic invertebrates, such as Daphnia.
Refer to section 13, Ecotoxicological expert report (BAGE: Evaluation of Environmental Fate and Ecotoxicity Properties) for further details of the evalaution of ecotoxicological properties of boric acid. The available data indicates boric acid is of low toxicity to aquatic invertebrates.
Glycerol
Glycerol is the other hydrolysis product of the reference substance, BAGE. It is not classified for the environment according to CLP or DSD.
Available data (see section 13) suggests that glycerol is of low toxicity to invertebrates.
Refer to section 13, Ecotoxicological expert report (BAGE: Evaluation of Environmental Fate and Ecotoxicity Properties) for further details of the evalaution of ecotoxicological properties of gycerol.
Supporting data
As the reference substance hydrolyses within less than an hour to its hydrolysis products; Boric acid and glycerol it was not feasible to conduct an algal inhibition study on the reference substance, as the result will be representative of the hydrolysis products Boric acid and glycerol.
A QSAR prediction has therefore been made for the reference substance (BAGE), using EPIWIN program ECOSAR (v0.99h).
The following predicitons for BAGE were made:
Daphnia: 48 hour EC50: 1.13 x 1011 mg/L
Daphnia: 16-day EC50: 8.84 x 107 mg/L
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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