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Diss Factsheets
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EC number: 947-943-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 27 February 2017 to 04 August 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: EU method A.24 (Partition coefficient (n-octanol / water), HPLC method)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- 2004
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
- Version / remarks:
- 1996
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Reaction products of Resin acids and Rosin acids, sodium salts and barium chloride
- Molecular formula:
- not applicable
- IUPAC Name:
- Reaction products of Resin acids and Rosin acids, sodium salts and barium chloride
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Appearance: Light tan powder
- Storage conditions: At room temperature
1
Results and discussion
Partition coefficientopen allclose all
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.2
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Peak area= 54%.
- Key result
- Type:
- log Pow
- Partition coefficient:
- 3.4
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Peak area= 36%.
- Key result
- Type:
- log Pow
- Partition coefficient:
- 3.2
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Peak area= 4.2%.
- Key result
- Type:
- log Pow
- Partition coefficient:
- 2.9
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Peak area= 5.6%.
- Details on results:
- - Retention times of reference substances used for calibration: see table below;
- Details of fitted regression line: log k' = 0.332 x log Pow – 0.848 (r = 0.998, n=12);
- Graph of regression line and chromatograms: see illustration;
- The chromatogram of the test item showed one major peak and three small test item peaks;
- Average retention data for test item: see table below;
- The value of log Pow obtained from duplicate measurements was within ± 0.1 log units.
Any other information on results incl. tables
Table: Results Partition coefficient n-octanol-water (HPLC method)
Substance |
Retention time (min) |
log Pow |
Pow |
Peak area |
||
RT1 |
RT2 |
mean |
||||
Formamide (t0) |
0.601 |
0.601 |
0.601 |
|
|
|
2-Butanone |
0.697 |
0.703 |
|
0.3 |
|
|
Nitrobenzene |
0.945 |
0.945 |
|
1.9 |
|
|
Bromobenzene |
1.554 |
1.551 |
|
3.0 |
|
|
Biphenyl |
2.590 |
2.582 |
|
4.0 |
|
|
Dibenzyl |
4.283 |
4.274 |
|
4.8 |
|
|
4,4’-DDT |
11.135 |
11.172 |
|
6.5 |
|
|
Test item – peak 1 |
1.414 |
1.414 |
1.414 |
2.9 |
8.8E2 |
5.6 |
Test item – peak 2 |
1.601 |
1.598 |
1.600 |
3.2 |
1.6E3 |
4.2 |
Test item – peak 3 |
1.765 |
1.764 |
1.765 |
3.4 |
2.6E3 |
36 |
Test item – peak 4 |
2.670 |
2.677 |
2.674 |
4.2 |
1.5E4 |
54 |
Remark: the log Pow values of the reference substances are according to OECD TG 117.
Applicant's summary and conclusion
- Conclusions:
- The log Pow of the test item component with peak area of 54%, 36%, 4.2% and 5.6% was determined to be 4.2, 3.4, 3.2 and 2.9, resp.
- Executive summary:
The log Pow of the substance was determined using the HPLC method in a GLP study according to EC A.8, OECD 117 and OPPTS 830.7570. Formamide was used as unretained substance. Duplicate injections of unretained substance, 6 reference substances and test item in an UPLC-PDA system. The mobile phase was 75/25 (v/v) methanol/buffer pH 7 and the wavelength of detection was 210 nm. The chromatogram of the test item showed four peaks.
Pow
log Pow
Peak area
(%)Test item – peak 1
8.8E2
2.9
5.6
Test item – peak 2
1.6E3
3.2
4.2
Test item – peak 3
2.6E3
3.4
36
Test item – peak 4
(Major component)1.5E4
4.2
54
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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