Registrirane tvari

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid
438-350-5 79349-82-9 Active Intermediate Joint Intermediate use only 21-12-2017 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-177-4 54639-48-4 Active Intermediate Joint Intermediate use only 03-06-2013 View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine
921-415-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine
918-453-6 - Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine
917-585-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
611-404-7 56610-72-1 Active Intermediate Joint Intermediate use only 02-11-2016 View substance registered dossier
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide
423-260-0 100988-63-4 Cease Manufacture NONS Individual Cease manufacture 29-10-2012 View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
239-787-2 15690-38-7 Active Intermediate Joint Intermediate use only 19-12-2018 View substance registered dossier
(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid
TACS
403-690-5 111298-82-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
250-099-1 30246-33-4 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
619-847-8 111298-82-9 Cease Manufacture Intermediate Individual Cease manufacture 26-03-2009 View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
258-907-4 53994-69-7 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
244-870-1 22252-43-3 Active Intermediate Joint Intermediate use only 16-12-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Cease Manufacture Full Joint Cease manufacture 03-05-2018 View substance registered dossier
(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde
482-190-9 127459-79-4 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one
881-148-0 1455358-14-1 Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)
605-420-3 165950-84-5 Active Full Joint ≥ 1 to < 10 tonnes 26-11-2020 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)
603-080-0 125572-93-2 Active Full Joint ≥ 1 to < 10 tonnes 17-12-2020 View substance registered dossier
(6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine
813-155-1 1585969-16-9 Active Intermediate Individual Intermediate use only 21-09-2016 View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid 438-350-5 79349-82-9 2012; 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2013 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-benzhydryl 3-hydroxy-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-177-4 54639-48-4 2021 View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine 921-415-1 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine 918-453-6 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine 917-585-1 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7S)-Benzhydryl 7-amino-7-methoxy-3-((1-methyl-1H-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 611-404-7 56610-72-1 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide 423-260-0 100988-63-4 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 2021 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active (6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid 403-690-5 111298-82-9 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 250-099-1 30246-33-4 2019 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 619-847-8 111298-82-9 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 258-907-4 53994-69-7 2019 View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde 482-190-9 127459-79-4 - View substance registered dossier
- - - - (6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde 482-190-9 127459-79-4 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one 881-148-0 1455358-14-1 2022 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1) 605-420-3 165950-84-5 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1) 605-420-3 165950-84-5 2018; 2020 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1) 603-080-0 125572-93-2 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1) 603-080-0 125572-93-2 2019; 2020 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S,12aR)-3,10-Dibromo-12,12a-dihydro-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazine 813-155-1 1585969-16-9 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier

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