Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-[2-[[2,2-dimethyl-3-[(1-oxododecyl)oxy]propylidene]amino]methylethoxy]-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1)

Hydrolysis

Link to relevant study record(s)

Reference

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

no guideline followed

Principles of method if other than guideline:

The purpose of the analysis was to perform a hydrolysis test to evaluate the abiotic degradation of SIKA Hardener LTJ in water and if hydrolysis is acid catalysed.

GLP compliance:

no

Radiolabelling:

no

Analytical monitoring:

yes

Buffers:

1mM NH4HCOO
1 % acetic acid in water

Details on test conditions:

short term-test :
Samples were dissolved in water free methanol with 1mM NH4HCOO (100 µg/mL) and were contacted with water or 1% acetic acid in water

test a) Hydrolysis with acetic water in changing mixing ratio in carrier flow (water / organic solvent)
test b) hydrolysis with bidest. water in changing mixing ratio water / organic solvent)

Long-term-test:
samples were dissolved in water free acetonitile (100µg/mL) and were contacted with water or 1% acetic acid in water

test c) Hydrolysis with acetic water contacted sample as a function of time
test d) Hydrolysis with bidest water contacted sample as a function of time
test e) Hydrolysis with slightly carbonated water contacted sample as a function of time

Number of replicates:

1

Positive controls:

no

Negative controls:

no

Transformation products:

not measured

Details on hydrolysis and appearance of transformation product(s):

Hydrolysis time
a) in acetous water (1% acetic acid): < 2 sec
b) in bidest. water: >> 2 sec
c) in acetous water as a function of time: ca. 5 min
d) in bidest. water as a function of time: ca. 20 h
e) in slightly carbonated water as a function of time: no data

Key result

DT50:

< 1 min

Type:

(pseudo-)first order (= half-life)

Validity criteria fulfilled:

yes

Conclusions:

Hydrolysis of SIKA Hardener LTJ was very fast and most rapid in acidic environment (acetous water) compared to basic environment (bidest. water). Due to the fast hydrolysis of the test substance of < 2 sec the half-life was determined to be < 1 min.

Executive summary:

The purpose of the analysis was to perform a hydrolysis test to evaluate the abiotic degradation of SIKA Hardener LTJ in water and if hydrolysis is acid catalysed. The substance was identified by flow injection via syring pump 12 µL/min with a FIMS-MS. The substance was tested in a short term test and in a long-term test. In the short-term test the samples were dissolved in water free methanole with 1 mM NH4HCOO (100 µg/mL) and were contacted with water or 1% acetic acid in water. In the long term test samples were dissolved in water free acetonitile (100 µg/mL) and were contacted with water or 1% acetic acid in water. The following results were received:

a) in acetous water (1% acetic acid): < 2 sec

b) in bidest. water: >> 2 sec

c) in acetous water as a function of time: ca. 5 min

d) in bidest. water as a function of time: ca. 20 h

 

Hydrolysis of SIKA Hardener LTJ was very fast and most rapid in acidic environment (acetous water) compared to basic environment (bidest. water). Due to the fast hydrolysis of the test substance of < 2 sec the half-life was determined to be < 1 min.

Description of key information

Hydrolysis of SIKA Hardener LTJ was very fast and most rapid in acidic environment (acetous water) compared to basic environment (bidest. water). Due to the fast hydrolysis of the test substance of < 2 sec the half-life was determined to be < 1 min.

Key value for chemical safety assessment

Half-life for hydrolysis:

1 min

Additional information

The purpose of the analysis was to perform a hydrolysis test to evaluate the abiotic degradation of SIKA Hardener LTJ in water and if hydrolysis is acid catalysed. The substance was identified by flow injection via syring pump 12 µL/min with a FIMS-MS. The substance was tested in a short term test and in a long-term test. In the short-term test the samples were dissolved in water free methanol with 1 mM NH4HCOO (100 µg/mL) and were contacted with water or 1% acetic acid in water. In the long term test samples were dissolved in water free acetonitile (100 µg/mL) and were contacted with water or 1% acetic acid in water. The following results were received:

a) in acetous water (1% acetic acid): < 2 sec

b) in bidest. water: >> 2 sec

c) in acetous water as a function of time: ca. 5 min

d) in bidest. water as a function of time: ca. 20 h

 

Hydrolysis of SIKA Hardener LTJ was very fast and most rapid in acidic environment (acetous water) compared to basic environment (bidest. water). Due to the fast hydrolysis of the test substance of < 2 sec the half-life was determined to be < 1 min.