Registration Dossier
Registration Dossier
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EC number: 200-064-1 | CAS number: 50-78-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 36 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- no exposure of sediment expected
Sediment (marine water)
- Hazard assessment conclusion:
- no exposure of sediment expected
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no exposure of soil expected
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Acute aquatic toxicity has been shown to be very low:
- neutralized substance EC50 48h in invertebrates > 1000 mg/L
- substance LC50 48h in fish > 1000 mg/L, so LC50 96h expected to be far higher than 100 mg/L
- substance EC50 72h in algae > 100 mg/L, at worst without neutralization
Chronic aquatic toxicity is similarly low, with the lowest NOEC (in Daphnia magna) far higher than 10 mg/L (ca. 60 mg/L) for the non-neutralized substance
As calculated by MacKay level I model, the substance is predicted to ge highly distributed (> 98%) in aquatic compartment. So sediment and soil hazard assessment was not considered as relevant, in addition to very low aquatic toxicity observed. Moreover, acetylsalicylic acid is readily biodegradable in aerobic as well as in anaerobic conditions, so the substance can be predicted not to be persistent in the environment.
Conclusion on classification
The substance is not classified as dangerous for environment on the following basis:
Acute aquatic toxicity has been shown to be very low:
- neutralized substance EC50 48h in invertebrates > 1000 mg/L
- substance LC50 48h in fish > 1000 mg/L, so LC50 96h expected to be far higher than 100 mg/L
- substance EC50 72h in algae > 100 mg/L, at worst without neutralization
The substance is readily biodegradable, both in aerobic and anaerobic conditions.
Log Kow is 1.19 allowng predicting no bioaccumulation potential.
Chronic aquatic toxicity is similarly low, with the lowest NOEC (in Daphnia magna) far higher than 10 mg/L (ca. 60 mg/L) for the non-neutralized substance
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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