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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from conference poster, full study not available

Data source

Reference
Reference Type:
other: conference poster
Title:
Toxicity of seven different nanoparticles to Eisenia fetida.
Author:
Heckman et al.
Year:
2008
Bibliographic source:
SETAC 25-29 May, 2008, Warsaw, Poland

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Titanium dioxide
EC Number:
236-675-5
EC Name:
Titanium dioxide
Cas Number:
13463-67-7
IUPAC Name:
dioxotitanium
Constituent 2
Chemical structure
Reference substance name:
Rutile (TiO2)
EC Number:
215-282-2
EC Name:
Rutile (TiO2)
Cas Number:
1317-80-2
Molecular formula:
O2Ti
IUPAC Name:
dioxotitanium
Details on test material:
* TiO2 nanoparticles (from Evonik Degussa), nominal particle size 21 nm, surface area 50 m²/g.
* bulk TiO2

Test organisms

Test organisms (species):
Eisenia fetida
Animal group:
annelids

Study design

Study type:
laboratory study
Substrate type:
natural soil
Limit test:
yes
Total exposure duration:
4 wk
Post exposure observation period:
hatching of produced cocoons was monitored during the following 4 weeks

Test conditions

Details on test conditions:
4 replicates
Nominal and measured concentrations:
nominal: 1000 mg/kg dry soil

Results and discussion

Effect concentrationsopen allclose all
Duration:
4 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: cocoon production
Remarks on result:
other: +/- 20% effect
Duration:
8 wk
Dose descriptor:
LOEC
Effect conc.:
<= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: hatchability
Remarks on result:
other: +/- 25% effect
Duration:
8 wk
Dose descriptor:
LOEC
Effect conc.:
<= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: juvenile production
Remarks on result:
other: +/- 50% effect
Duration:
4 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
bulk TiO2
Basis for effect:
other: cocoon production
Duration:
8 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
bulk TiO2
Basis for effect:
other: hatchability and juvenile production
Details on results:
data derived from graph

Applicant's summary and conclusion