α,α-dichlorotoluene

Exposure related observations in humans: other data

Administrative data

Endpoint:

exposure-related observations in humans: other data

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: The study is insufficiently described as sampling and quantification are not known. Therefore, this study should be considered as not assignable due to insufficient documentation.

Data source

Reference

Reference Type:

publication

Title:

Occupational exposure to benzyl chloride and benzal chloride due to contaminated butyl benzyl phtalate

Author:

Rittfeld L.M.

Year:

1983

Bibliographic source:

Scand. J. Work Environ Health, 9, 367-368.

Materials and methods

Type of study / information:

Occupational exposure to benzal chloride

Endpoint addressed:

not applicable

Principles of method if other than guideline:

Exposure levels to benzal chloride have been assessed in industrial PVC flooring processors plants

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

α,α-dichlorotoluene

EC Number:

202-709-2

EC Name:

α,α-dichlorotoluene

Cas Number:

98-87-3

Molecular formula:

C7H6Cl2

IUPAC Name:

(dichloromethyl)benzene

Constituent 2

Reference substance name:

Dichloromethylbenzene

EC Number:

249-854-8

EC Name:

Dichloromethylbenzene

Cas Number:

29797-40-8

IUPAC Name:

(dichloromethyl)benzene

Details on test material:

- Name of test material (as cited in study report): benzal chloride
No further data

Method

Details on study design:

Exposure levels of benzal chloride were measured in air of manufacturing plant of PVC floorings near manufacturing lines.

Exposure assessment:

measured

Results and discussion

Results:

0.15 mg/m³ near the manufacturing lines of PVC floorings was detected and 0.2 mg/m³ in air near surface film manufacturing lines was detected. Benzal chloride was a contaminant of butyl benzyl phthalate used as a plasticizer in PVC floorings. Benzal chloride was also detected in the atmosphere over a 10-day old vinyl floor tile. Furthermore, at room temperature, the emission rate of benzal chloride from PVC floorings was calculated to be about 0.01 mg per hour and square meter.

Applicant's summary and conclusion

Conclusions:

In this study, the authors found that workers in a PVC floorings plant were exposed to 0.15 mg/m³ or 0.2 mg/m³ near processing machines of benzal chloride as a contaminant of butyl benzyl phthalate.

Executive summary:

In this study, exposure levels of benzal chloride were measured in air of manufacturing plant of PVC floorings near manufacturing lines after some cases of occupational irritation were noted.

0.15 mg/m³ of benzal chloride near the manufacturing lines of PVC floorings was detected and 0.2 mg/m³ in air near surface film manufacturing lines was detected. Benzal chloride was determined to be a contaminant of butyl benzyl phthalate used as a plasticizer in PVC floorings. Benzal chloride was also detected in the atmosphere over a 10-day old vinyl floor tile. Furthermore, at room temperature, the emission rate of benzal chloride from PVC floorings was calculated to be about 0.01 mg per hour and square meter.

However, there is no mention of the quantification method neither on the sampling method. Results are not sufficiently described and specific context of the occupational exposure is not clear. Therefore, this study should be considered as not assignable ude to insufficient documentation.