4-chlorophthalic anhydride

Oxidising properties

Administrative data

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2004

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2004

Report date:

2004

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

1992

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: EPA OPPTS 830.6314 (Oxidising or Reducing Action)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

4-chlorophthalic anhydride

EC Number:

204-251-9

EC Name:

4-chlorophthalic anhydride

Cas Number:

118-45-6

Molecular formula:

C8-H3-Cl-O3

IUPAC Name:

5-chloro-1,3-dihydro-2-benzofuran-1,3-dione

Study design

Contact with:

other: zinc powder, ammonium phosphate, calcium hypochlorite, water and cellulose

Results and discussion

Test results (Oxidising solids)

Test results (Oxidising solids) 1

Key result

Sample tested:

other: zinc powder, ammonium phosphate, calcium hypochlorite, water and cellulose

Parameter:

other: temperature

Remarks on result:

other: no increase in temperature

Test results (Oxidising solids) 2

Key result

Sample tested:

other: 67%, 50%, 34% sample-to-cellulose ratio

Parameter:

other: extent of combustion

Remarks on result:

other: less extent of combustion relative to pure cellulose

Any other information on results incl. tables

Chemical Compatibility (EPA OPPTS 830.6314)

A series of experiments were conducted in which 4-chlorophthalic anhydride (4CLPA) was mixed with zinc powder (reducing agent), ammonium phosphate (fire-fighting agent; as aqueous solution), calcium hypochlorite (oxidizing agent; as aqueous solution) and water. The temperatures of these mixtures were monitored until thermal equilibrium was achieved. In all of these experiments, the temperatures of the undisturbed mixtures were generally not significantly greater than ambient temperature, and were never different from ambient temperature by more than 5°C, indicating that 4CLPA did not pose a hazard due to heat liberation when mixed with these substances.

Combustion with Cellulose (EU Method A17)

Three mixtures of powdered 4CLPA and cellulose were prepared containing 67%, 50%, and 34% 4CLPA (by weight). The mixtures were formed into conical piles. When the piles were contacted with a propane flame, the extent of combustion was less than that observed for pure cellulose, as indicated by mass loss of the piles and visual observations. Therefore, the presence of 4CLPA reduced the extent of combustion of the cellulose/4CLPA mixtures relative to pure cellulose, and no further testing was warranted. Based on these results, 4CLPA was not considered to exhibit vigorous oxidizing behavior as defined in EU Method A 17.a

Applicant's summary and conclusion

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance was considered to be not oxidising.

Executive summary:

The oxidizing properties were assessed in a EU method A.17 and EPA OPTTS 830.6314 study, performed in compliance with GLP criteria. A series of experiments were conducted in which 4-chlorophthalic anhydride (4CLPA) was mixed with zinc powder (reducing agent), ammonium phosphate (fire-fighting agent; as aqueous solution), calcium hypochlorite (oxidizing agent; as aqueous solution) and water. The temperatures of these mixtures were monitored until thermal equilibrium was achieved. In all of these experiments, the temperatures of the undisturbed mixtures were generally not significantly greater than ambient temperature, and were never different from ambient temperature by more than 5°C, indicating that 4CLPA did not pose a hazard due to heat liberation when mixed with these substances. Additionally, three mixtures of powdered 4CLPA and cellulose were prepared containing 67%, 50%, and 34% 4CLPA (by weight). The mixtures were formed into conical piles. When the piles were contacted with a propane flame, the extent of combustion was less than that observed for pure cellulose, as indicated by mass loss of the piles and visual observations. Therefore, the presence of 4CLPA reduced the extent of combustion of the cellulose/4CLPA mixtures relative to pure cellulose, and no further testing was warranted. Based on these results, 4CLPA was not considered to exhibit vigorous oxidizing behavior.