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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Short description of key information:
For anthracene oil containing less than 50 ppm of BaP, weakly mutagenic potential may be observed in vitro:
an Ames test in the presence of metabolising enzymes was positive only in TA 100 at cytotoxic concentrations;
a mouse-lyphoma assay (MLA, OECD 476) weakly positive for a closely structure-related tar oil;
a cytogenetic assay (chromosomal aberration, OECD 473) came out negative for the very same tar oil.

An in-vivo micronucleus test in mice using the structure-related tar oil gave no evidence of a mutagenic potential.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The low-grade mutagenic potential eventually detected in in-vitro standard assays conducted with tar oils containing BaP levels of =< 50 ppm has not been confirmed in an mammalian erythrocyte micronucleus assay.

Anthracene oil (BaP =< 50 ppm) is supposed to reflect similar mutagenic properties.

Thus classification according to Regulation (EC) No 1272/2008 or Directive (EU) 67/548/EEC is not required.