Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

mode of degradation in actual use
Type of information:
experimental study
Adequacy of study:
key study
4 (not assignable)

Data source

Reference Type:
review article or handbook
Handbook of Chemical Property Estimation Methods
[(1) Atkinson R; (2) Meylan WM, Howard PH; (3) Lyman WJ et al
Bibliographic source:
Environ Toxicol Chem 7: 435-62 (1988); Chemosphere 26: 2293-99 (1993) ; . Washington, DC: Amer Chem Soc pp. 7-4, 7-5 (1990)

Materials and methods

Test guideline
no guideline available
Principles of method if other than guideline:
Toxnet database
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
EC Number:
EC Name:
Cas Number:

Results and discussion

Applicant's summary and conclusion

Executive summary:

Environmental Abiotic Degradation:

The rate constant for the vapor-phase reaction of 5-nitro-o-anisidine with photochemically-produced hydroxyl radicals has been estimated as 3.3X10-11 cu cm/molecule-sec at 25 deg C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 12 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). 5-Nitro-o-anisidine is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3). Aromatic amines such as aniline have weak absorption bands that extend beyond 290 nm(4), therefore p-anisidine may be susceptible to direct photolysis, but the kinetics of this reaction are unknown. Aniline has been shown to undergo indirect photolysis in natural waters containing humic acids(5), therefore it is expected that p-anisidine may also undergo indirect photolysis in natural water.