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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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In vitro experiments demonstrated that strontium is able to stimulate the release of histamine from mast cells but with a lower efficiency than calcium (Foreman and Mongar, 1972; Foreman, 1977). In addition, strontium stimulated the secretion of 5-hydroxytryptamine in washed human platelets (Best et al., 1981). It was concluded that strontium activates the liberation of arachidonate from membrane phospholipids, with the subsequent biosynthesis of thromboxane A2. The addition of strontium chloride to diluted rabbit serum in vitro inhibited the bactericidal actions of the serum (Toshioka et al., 1974). This effect was attributed to the inhibition of the complement.

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