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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from HSDB authoritative database
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Environmental bioconcentration factor of the test chemical was estimated using a partition coefficient and a regression-derived equation.
GLP compliance:
not specified
Radiolabelling:
not specified
Vehicle:
not specified
Test organisms (species):
other: Fish
Route of exposure:
aqueous
Test type:
not specified
Water / sediment media type:
natural water: freshwater
Reference substance (positive control):
not specified
Details on estimation of bioconcentration:
BASIS FOR CALCULATION OF BCF
using a log Kow of 1.9
Key result
Type:
BCF
Value:
8 dimensionless
Basis:
whole body w.w.
Calculation basis:
other: BCF value of test chemical was estimated using a log Kow of 1.9 and a regression derived equation.
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
The estimated BCF (bioaccumulation factor) of test chemical was determined to be 8.0 dimensionless.
Executive summary:

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 1.9 and a regression derived equation. The estimated BCF (bioaccumulation factor) value of test chemical in fish was determined to be 8.0 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-bioaccumulative in aquatic organisms.

Description of key information

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculatedusing a log Kow of 1.9 and a regression derived equation. The estimated BCF (bioaccumulation factor) value of test chemical in fish was determined to be 8.0 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-bioaccumulative in aquatic organisms.

Key value for chemical safety assessment

BCF (aquatic species):
8 dimensionless

Additional information

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculatedusing a log Kow of 1.9 and a regression derived equation. The estimated BCF (bioaccumulation factor) value of test chemical in fish was determined to be 8.0 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-bioaccumulative in aquatic organisms.

 

In addition to this, bioaccumulation endpoint can also be considered for waiver as per in accordance with column 2 of Annex IX of the REACH regulation, testing for this endpoint is scientifically not necessary and does not need to be conducted since the test chemical has a low potential for bioaccumulation based on logKow ≤ 3.