Registration Dossier
Registration Dossier
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EC number: 246-690-9 | CAS number: 25167-70-8
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
The TLM-EqP predicted effect values for 2,4,4-trimethylpentene were 474.133 and 58.645 mg/kg soil dw for short-term (14-day LC50) and long-term effects (21-day EC10) to Brassica rapa, respectively.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 474.133 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 58.645 mg/kg soil dw
Additional information
This substance is considered to have a Soil Hazard Category 4 classification because no biodegradation was observed during the test and the has an EC50< 1 mg/L. Therefore, we are required to conduct a conduct long-term toxicity tests according to the standard information requirements Annex X (invertebrates and plants), and choose the lowest value for derivation of PNECsoil according to ECHA (2017) Guidance on information requirements and chemical safety assessment, chapter R7c: endpoint specific guidance.
The registered substance is highly volatile which complicates environmental testing. Therefore, a modeling framework is needed to account for the bioavailability of the substance to perform read-across and data gap filling. The TLM-EqP modeling has been validated as a suitable method for predicting effect values in terrestrial plants. The TLM-EqP predicted effect values for xxx were xx and xx mg/kg soil dw for short-term (14-day LC50) and long-term effects (21-day EC10) to Avena sativa, respectively. The TLM-EqP predicted effect values for 2,4,4 -trimethylpentene were 474.133 and 58.645 mg/kg soil dw for short-term (14-day LC50) and long-term effects (21-day EC10) to Brassica rapa, respectively.
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