Registration Dossier
Registration Dossier
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EC number: 233-334-2 | CAS number: 10124-43-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Relevant and reliable data that could be used for classification for freshwater invertebrates were retrieved for 10 different species. The LC50s ranged from 0.61 mg Co/L for the cladoceran, Ceriodaphnia dubia to 7219 mg Co/L for Brachycentrys americansus. Relevant and reliable data that could be used for classification for marine invertebrates were retrieved for 4 different species. The LC50s ranged from 2.32 mg Co/L for the sand dollar, Dendraster excentricus to 3.70 mg Co/L for the pacific oyster, Crassostrea sp. Test results were obtained in experiments that followed international accepted guidance and were based on measured levels of dissolved cobalt as cobalt chloride.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- LC50
- Effect concentration:
- 0.61 mg/L
Marine water invertebrates
Marine water invertebrates
- Dose descriptor:
- LC50
- Effect concentration:
- 2.32 mg/L
Additional information
Freshwater:
From the database of acute cobalt toxicity to freshwater invertebrates, 41 individual LC50 values for 10 different individual species were reported. The LC50s ranged from 0.61mg Co/Lfor the cladoceran, Ceriodaphnia dubia tested in soft, dissolved organic matter-free water (CDI, 2005) to 7219 mg Co/L for the midge, Brachycentrus americansus (Pacific EcoRisk, 2005). No freshwater acute invertebrate toxicity studies were used to derive the HC5 and freshwater PNEC.
Marine:
From the database of acute cobalt toxicity to marine invertebrates, 4 LC50 values are reported for 4 species. The values range from 2.32 mg Co/L for the sand dollar, Dendraster excentricus (CDI 2010c) to 2.62 for Mytilus sp. (CDI 2010a), to 2.83 for Stronglyocentrotus purpuratus (CDI 2010d)and 3.70 mg Co/L for the pacific oyster, Crassostrea sp.(CDI 2010b).
No short-term marine aquatic invertebrate tests are used in the marine PNEC derivation.
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