Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-662-2 | CAS number: 67-64-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Freshwater species:
Microcystis aeruginosa: 8 d LOEC=530 mg/L nominal
Saltwater species:
Prorocentrum minimum: 96 h NOEC=430 mg/L nominal
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 530 mg/L
- EC10 or NOEC for marine water algae:
- 430 mg/L
Additional information
There are a lot of studies dealing with the toxicity of acetone to freshwater and saltwater algae. Only the study with Microcystis aeruginosa, however, fulfills the validity critereria of current guidelines (in deviation from guideline light/dark cycles were employed in studies with freshwater and saltwater species).
Freshwater species:
For the cyanobacterium Microcystis aeruginosa a 8 d TT (NOEC) of 530 mg/L (nominal) was determined. It has to be noted that after 8 days exposure the algae might not longer be in the exponential growth phase which may have a negative influence on the test result. Therefore, the effect values found in this test, should be used with care.
The 48/96 h NOEC values reported in other studies ranged from 3400 mg/L (48 h) nominal for Chlorella pyrenoidosa to 7000 mg/L nominal for Selenastrum capricornutum (96 h). These data support the low toxicity of acetone to freshwater algae and cyanobacteria.
Saltwater species:
The NOEC values ranged from 430 mg/L nominal (96 h) for Prorocentrum minimum to 6000 mg/L nominal (120 h) for Skeletonema costatum. For Skeletonema costatum a 5 d EC50=11798 mg/L nominal was determined. However, these data are well within the range of typical species variability in sensitivity toward toxicants.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.