Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-545-4 | CAS number: 108-05-4
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC, LOEC and MATC for this study are 0.551, 0.930 and 0.716 mg/L. Recalculated NOEC = 0.16 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.16 mg/L
Additional information
The study by Marino et al., (2003) was carried out in accordance with GLP and recognised test guidelines. The NOEC, LOEC and MATC reported in this study are 0.551, 0.930 and 0.716 mg/L.This result was not based on the Time Weighted Average, recommended in the OECD test guidelines, and therefore the NOEC has been recalculated, using the raw data provided in the report to give a NOEC of 0.16 mg/L. A notable restriction of this study is that the experimenters had difficulty in maintaining the concentration of test substance during the exposure period due in part to the physical and chemical properties of vinyl acetate, and also likely due to a build up of biomass and/or polymerised test material. This has been taken into account when scoring the reliability of this study and assessing whether it can be used.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
