Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
other information
Study period:
No data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data reported in handbook: any details on the test substance, the protocol and the results are not available (old study)
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1999

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Hexamethylenediamine
EC Number:
204-679-6
EC Name:
Hexamethylenediamine
Cas Number:
124-09-4
Molecular formula:
C6H16N2
IUPAC Name:
hexane-1,6-diamine
Test material form:
solid
Details on test material:
Appearance: clear crystalline solid mass at room temperature
Storage condition: store in refrigerator
Stability under correct storage conditions (expiry date): October 18, 2017

Test animals

Details on test animals or test system and environmental conditions:
No data

Administration / exposure

Details on inhalation exposure:
No data
Duration of exposure:
ca. 10 min
Details on study design:
No data
Statistics:
No data

Results and discussion

Any other information on results incl. tables

No data

Applicant's summary and conclusion

Interpretation of results:
other:
Remarks:
Criteria used for interpretation of results: EU
Conclusions:
LDLo = 750 mg/m3 in mice exposed to HMD for 10 minutes
Executive summary:

LCLo = 750 mg/m3 in mice exposed to HMD for 10 minutes