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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Description of key information

The melting point of quinine is in the range of 174 - 178°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
174 °C

Additional information

According to EPI Suite v.4.11. and ChemIDplus Advanced the experimentally determined melting point of quinine is 57 °C. Details on the method are not available. But according to the publication of Smith et al., 1973 and the peer-reviewed database, GSBL, the melting point of quinine is in the range from 172 - 177 °C. Further, according to the Deutsches Arzneimittelbuch 7. issue, the melting point of quinine is in the range of 174 - 178 °C. The melting point of quinidine, a stereoisomer of quinine, with a value of 174 ° is also available in EPI Suite v.4.11 and conforms with the values of melting point of the peer-reviewed database, GSBL. Thus, for the melting point a mean value of 174 °C was considered as appropriate value.