Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute toxicity to fish:

No toxic effects 2,2-dimethylpropan-1,3-diyl dibenzoate against fish were observed at the limit of water solubility under exposure conditions. The toxicity to fish was determined at LC50 of >0.280 mg/L after 96 hours. All results are expressed in terms of geometric mean measured concentrations.

 

Acute toxicity to daphnia:

After 48 hours an EC50 of higher than 0.90 mg/l was measured. No toxic effects of 2,2-dimethylpropan-1,3-diyl dibenzoate against Daphnia were observed at a limit of water solubility under exposure conditions. The results are expressed in terms of geometric mean measured concentrations.

 

Toxicity to freshwater algae:

In a weight-of-evidence approach it could be shown that 2,2-dimethylpropane-1,3-diyl dibenzoate as such does not cause effects to algae.

Effects observed in one study relate to the main by-product 3-hydroxy-2,2-dimethylpropyl benzoate that was unintentionally enriched during test solution preparation due to its high water solubility.

In a study with purified test item no effects to algae were observed up to the limit of the water solubility.

 

Toxicity to microorganisms:

After three hours 2,2-dimethylpropan-1,3-diyl dibenzoate showed 5% respiration inhibition of activated sludge at a test item concentration of 1000 mg/L. The EC50 value of higher than 1000 mg/L and the NOEC equal or higher than 1000 mg/L were determined. The effect values relate to a nominal concentration.

 

All toxicity studies mentioned above are classified as acceptable and satisfy the guideline requirements for the toxicity studies on acute toxicity to aquatic organisms.