2,4,6-trichloroaniline

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.023 mg/L

Assessment factor:

100

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.023 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.002 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

0.46 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

1.477 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.148 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.703 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

Classification of 2, 4, 6-trichloroaniline for effects in the environment

In determining the classification appropriate to 2,4,6-trichloroaniline, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 

 

Persistence

 

Reliable studies are available to demonstrate that 2,4,6-trichloroaniline is persistent in the aquatic environment. Moreover, its persistent characteristics (based on WOE) is also observe in the sediment and soil compartment and hence it has been concluded that 2,4,6-trichloroaniline is persistent in nature. However, since there is no identified diffusion of the substance in the sediment and hence persistence in the sediment compartment is not likely to be critical.

 

2,4,6-trichloroaniline is classified as a persistent (P) chemical. 

 

Potential to accumulate

The estimated log Kow values for 2,4,6-trichloroaniline is less than 4 (Log Kow = 3.52). The potential for 2,4,6-trichloroaniline to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 2000.  The estimated BCF of 2,4,6-trichloroaniline is highest 147 dimensionless and below the threshold of 2000. 

 

Thus, 2,4,6-trichloroaniline does not satisfy the criterion for classification as bio-accumulative (B).

 

The toxicity values of fish, invertebrates and algae are LC50 = 5.3 mg/L, LC50 = 2.3 mg/L and EC50 = 4.445 mg/L, respectively. These values suggest classification for aquatic toxicity will be applicable for all of the tropic levels. Thus, the chemical is classified in the Aquatic Chronic 2 category.

 

Also, based upon the repeated dose toxicity and reporoductive toxicity end points, 2,4,6-trichloroaniline satisfies the criteria for classification as toxic (T).

 

In conclusion, since the chemical is not bio-ccumulative, but persistent and toxic; it can beinferred that 2,4,6-trichloroaniline is not a PBT (including vPvB) substance.

Conclusion on classification

Classification for Aquatic Toxicity is triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.