Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
evaluation of existing test and data
Type of information:
other: Expert Judgement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
other: expert judgement
Title:
Unnamed
Year:
2017

Materials and methods

Objective of study:
absorption
distribution
excretion
metabolism
toxicokinetics
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Expert judgement with evaluation of toxicokinetic, metabolism and excretion.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate
EC Number:
217-699-5
EC Name:
Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate
Cas Number:
1934-21-0
Molecular formula:
C16H12N4O9S2.3Na
IUPAC Name:
trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate
Test material form:
solid: particulate/powder
Details on test material:
No data
Radiolabelling:
yes

Results and discussion

Metabolite characterisation studies

Metabolites identified:
yes

Applicant's summary and conclusion

Conclusions:
Not bioaccumulative
Executive summary:

Based on the data available, Acid Yellow 23 undergoes to a metabolic degradation into metabolites which are excreted by urine and faeces and therefore Acid Yellow 23 can be considered as not-bioaccumulative.