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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species, other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from authorative database
Qualifier:
according to guideline
Guideline:
other: Refer below principle
Principles of method if other than guideline:
Environmental Bioconcentration of test chemical was determine using an estimated log Kow of 2.61 and a regression derived equation.
GLP compliance:
not specified
Radiolabelling:
not specified
Vehicle:
not specified
Test organisms (species):
other: fish
Route of exposure:
aqueous
Test type:
not specified
Water / sediment media type:
natural water: freshwater
Reference substance (positive control):
not specified
Key result
Type:
BCF
Value:
57 dimensionless
Basis:
whole body w.w.
Calculation basis:
other: regression-derived equation
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
From authorative database HSDB an estimated BCF of 57 was calculated for test chemical using an estimated log Kow of 2.61 and a regression derived equation.
Executive summary:

From authorative database HSDB, an estimated BCF of 57 was calculated for test chemical, using an estimated log Kow of 2.61and a regression derived equation.This BCF suggests the potential for bioconcentration in aquatic organisms is moderate.

Description of key information

From authorative database HSDB, an estimated BCF of 57 was calculated for test chemical, using an estimated log Kow of 2.61and a regression derived equation.This BCF suggests the potential for bioconcentration in aquatic organisms is moderate.

Key value for chemical safety assessment

BCF (aquatic species):
57 dimensionless

Additional information

Experimental study and predicted data of the target chemical were reviewed for the bioaccumulation end point which are summarized as below:

 

In an experimental study from authoritative database, an estimated BCF of 57 was calculated for test chemical, using an estimated log Kow of 2.61and a regression derived equation.

 

In a prediction done using the BCFBAF (v3.00) model of EPI suite, the estimated bio concentration factor (BCF) for test chemical is 20.1 L/kg wet-wt.

 

From Scifinder database, the bioconcentration factor (BCF) for target chemical was predicted to be 38.0 at pH range 1-8, 36.6 at pH 9 and 27.6 at pH 10 at temperature 25 deg.C.

 

Using the Chemspider - ACD/PhysChem Suite prediction model the Bioconcentration factor (BCF) for target chemical was estimated to be 36.5 at pH 5.5 and 7.4 at temperature 25°C.

 

On the basis of above results, it can be concluded that the BCF value of test chemical was evaluated to be ranges from 20.1 to 57, respectively, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.