Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 208-395-3 | CAS number: 526-75-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
- General notes: Wear proper personal protective equipments.
- Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
- Skin contact: Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
- Eye contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids. Get medical aid immediately.
- Ingestion: Do not induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
Fire-fighting measures
- Suitable extinguishing media - In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
- Unsuitable extinguishing media - Extinguishing media should not contain alcohols, cyanides, iodine, strong bases and carbonates.
- Special hazard arising from the substance - Reaction of Chloral hydrate with hydroxylamine produces toxic hydrogen cyanide gas. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
- Advice for firefighters - As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Accidental release measures
- Protective equipment: Use self contained breathing apparatus, protective equipments like gloves, goggles, boots etc.
- Emergency procedures: Keep away from light, moisture and air.
- Removal of ignition sources: Keep away from all sources of ignition.
- Provision of sufficient ventilation: Provide adequate ventilation.
- Control of dust: Do not breathe dust, gas, vapor.
- Environmental precautions: Avoid release to the environment. Prevent entry to sewers and public waters.
- Methods and material for containment and cleaning up: Clean up any spills as soon as possible, using an absorbent material to collect it. Use suitable disposal containers.
Handling and storage
- Precautions for safe handling: : Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Local exhaust and general ventilation must be adequate to meet exposure standards. Close container tightly after use.
- Incompatible substances or mixtures: Keep away from alcohols, cyanides, iodine, strong bases, carbonates.
- Evaporative conditions: Minimize dust generation and accumulation. Store in a tightly closed container. Store in a well-ventilated place
- Potential ignition sources: Keep away from ignition sources, flames and sparks.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2261
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2261
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Marine transport (UN RTDG/IMDG)
- UN number:
- 2261
Shipping information
- Chemical name:
- 2,3-xylenol
- Marine pollutant
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2261
Shipping information
- Chemical name:
- 2,3-xylenol
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Exposure controls / personal protection
Appropriate engineering controls
• Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
• Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Individual protection measures
(a) Eye / face protection: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN 166.
(b) Skin protection:
(i) Hand protection: Wear appropriate protective gloves to prevent skin exposure. Chemical resistant protective gloves (EN374). Suitable for splash and prolonged contact: nitrile rubber, minimum layer thickness 0.11 mm, break through time: 480 min
(ii) Other: Wear appropriate protective clothing to minimize contact with skin.
(c) Respiratory protection: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Stability and reactivity
- Reactivity: Reaction of chloral hydrate with hydroxylamine produces toxic hydrogen cyanide gas.
- Chemical stability: Stable under normal temperatures and pressures. Sensitive to air, moisture and light
- Possibility of hazardous reactions: Hazardous polymerization has not been reported.
- Conditions to avoid: Excess heat, dust generation, light, exposure to air.
- Incompatible materials: Incompatible with alcohols, cyanides, iodine, strong bases, carbonates.
- Hazardous decomposition products: Chlorine, hydrogen chloride, carbon monoxide, carbon dioxide, chloroform,
Disposal considerations
- Sewage disposal: Do not allow to enter sewers or natural waters. Avoid release to the environment. Dispose in a safe manner in accordance with local/national regulations.
- Special precautions: Empty containers must be decontaminated before returning for recycling
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.