2-[3-(4-propyl-heptyl)-morpholin-4-yl]-ethanol hydrochloride

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

August 10, 2016 - October 21, 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

no

GLP compliance:

no

Type of method:

ring method

Specific details on test material used for the study:

Internal sample code: 2929564-001
Purity: 100.3% w/w
Batch number: 2510468

Key result

Surface tension:

ca. 30.6 mN/m

Temp.:

20 °C

Conc.:

1 g/L

The determinations were performed at 20.0 ±and at this temperature the tabulate value for water is 72.75 mN/m.

 

After zero point adjustment, the surface tension of the distilled water (sg) was determined to be 71.53 mN/m; therefore the calibration factor was calculated to be f (water) = 1.0170.

 

According to the method’s indications, the test item was tested at 1 g/L concentration inwater.

The test item solutions at the above described concentration was maintained at 20 ±in a thermostatic liquid bath and then tested.

 

Six measurements were performed for each solution at 20.0°C. Data are reported in Tables 1, 2 and 3.

 

TABLE 1.  Delmopinolo HCl: Surface tension

 

Measurements	Test item 1 g/L solution (mN/m)
1^st	32.2
2^nd	32.0
3^rd	31.9
4^th	31.7
5^th	32.0
6^th	32.1
Average values (a)	32.0
S.D.	0.16
RSD%	0.51%

 

 

 

 

 

TABLE 2. Delmopinolo HCl: Surface tension. Correction with water calibration factor

 

	Average values (a) (mN/m)	f (water) calibration factor	Corrected values (b) (mN/m)
Test item Solution at 1 g/L	32.0	1.0170	32.5

 

 

 

TABLE 3. Delmopinolo HCl: Surface tension. Correction with method interpolation

 

Test item solution	Corrected values (b) (mN/m)	Tab. X1 (mN/m)	Tab. X2 (mN/m)	Tab. Y1 (mN/m)	Tab. Y2 (mN/m)	Slope (m)	Interc. (q)	St (mN/m)
Test item Solution at 1 g/L	32.5	34.1	36.1	36.0	38.0	1.0000	1.9000	30.6

 

Note.Y1 and Y2 are the surface tension values respectively lower and higher of the experimental datum obtained after first correction with water calibration. X1 and X2 are the correspondent values found in the table reported in the A.5 method.

Using these values a linear interpolation was calculated through the following formula:

 

Y = m X + q

 

where:

 

m= Slope of the linear interpolation (from the table)

q= Interception value (mN/m) of the linear interpolation (from the table)

Conclusions:

From the obtained experimental data according to the A.5 method in Council Regulation (EC) No 440/2008 of 30 May 2008 and OECD Guideline No. 115, it can be concluded that the surface tension at 20°C (± 0.5°C) for the Delmopinolo HCl Technical sample at 1 g/L concentration in water is 30.6 mN/m.

According to the interpretation of the results suggested in the A.5 method, the Delmopinolo HCl Technical sample should be regarded as a surface-active material.

Executive summary:

Delmopinolo HCl Technical sample should be regarded as a surface-active material.

Key value for chemical safety assessment

Surface tension:

30.6

Additional information

The sample should be regarded as a surface-active material.