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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16th June 1999 - 1st February 2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
429-080-9
EC Name:
-
Cas Number:
198904-85-7
Molecular formula:
C17 H21 N3 O2
IUPAC Name:
Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
Test material form:
solid: bulk
Specific details on test material used for the study:
Identity of test material same as for substance defined in section 1

Test solutions

Vehicle:
no
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: No auxiliary solvents were required

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
semi-static

Test conditions

Hardness:
55.6 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
ca. 20 mg/L
Basis for effect:
mortality (fish)
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 20 mg/L
Basis for effect:
mortality (fish)
Key result
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
ca. 20 mg/L
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 17.69 mg/L
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
ca. 25 mg/L
Basis for effect:
mortality (fish)
Key result
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
> 12.5 mg/L
Basis for effect:
mortality (fish)
Details on results:
%Concentration loss over test: 2 ... 11

Applicant's summary and conclusion

Conclusions:
LC50 figures for other time points were not calculated, but there was mortality at 25 and 50 mg/l within the first hour of exposure. At 12.5 mg/l, severe toxic signs were apparent throughout the study, but there was no mortality.