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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2010
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient information to perform an assessment on reliability.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
EC Number:
603-316-2
Cas Number:
129050-27-7
Molecular formula:
C18H20FNO2
IUPAC Name:
(1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study reports): JNJ-17298957-AAA (T001592)
- Physical state: solid (powder)
- Appearance: White powder
Specific details on test material used for the study:
Batch n°: Jverpoor-p-02-094-01

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
methanol
Solubility:
6.2 other: g/100 ml
Temp.:
20 °C
Medium:
ethanol
Solubility:
3.8 other: g/100 ml
Temp.:
20 °C
Medium:
acetone
Solubility:
8.4 other: g/100 ml
Temp.:
20 °C
Medium:
other: N,N-dimethylacetamide
Solubility:
26 other: g/100 ml
Temp.:
20 °C
Medium:
other: N,N-dimethylformamide
Solubility:
23 other: g/100 ml
Temp.:
20 °C
Medium:
other: dichloromethane
Solubility:
18 other: g/100 ml
Temp.:
20 °C

Any other information on results incl. tables

Not applicable.

Applicant's summary and conclusion