Registration Dossier
Registration Dossier
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EC number: 203-981-5 | CAS number: 112-52-7
Endpoint summary
Administrative data
Description of key information
The only data for the assessment of repeated dose toxicity of lauryl chloride are publicly available, but proprietary data, which have been submitted to the US EPA under the Toxic Substances Control Act (TSCA). In a combined 28-day oral repeated-dose/reproductive screening study in rats (according to OECD 422 and US EPA TSCA 799.9365), the systemic NOAEL was at 100 mg/kg based on lower mean body weight gains and food consumption at 1000 mg/kg and lower mean thymus gland weights at 300 and 1000 mg/kg.
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
Information on repeated dose toxicity of lauryl chloride was obtained in a combined 28-day oral repeated-dose/reproductive screening study in rats. In this study, the systemic NOAEL was at 100 mg/kg. Based on the results of this study there are no hints for repeated dose toxicity of lauryl chloride that would lead to a classification according to Regulation (EC) 1272/2008.
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