1-chloro-2-methylpropan-2-ol

GHS

General Information

Name:

1-chloro-2-methylpropan-2-ol

Implementation:

EU

Type of classification:

self-classification

Remarks:

This substance is currently listed on the substances list published by ECHA of those who has met REACH Annex III criteria.

The Annex III inventory is an advisory list, there are not detailed information about the used model and the predictions do not follow OECD principles.

Therefore, the following data can only be used as screening information, but they are not to be considered relevant for the classification and labelling:

# Suspected carcinogen: The Toolbox profiler Carcinogenicity (genotox and nongenotox) alerts by ISS gives an alert for carcinogenicity

# Suspected hazardous to the aquatic environment: DEMETRA Daphnia Magna toxicity model in VEGA (Q)SAR platform predicts that the chemical has a 48h EC50 of 5.98 mg/L (moderate reliability);The Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 63.29 mg/L; The Danish QSAR database contains information indicating that the substance has a 96h EC50 to green algae of <1 mg/L

# Suspected mutagen: The Toolbox profiler in vitro mutagenicity (Ames test) alerts by ISS gives an alert for mutagenicity; CAESAR Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Suspect Mutagen (good reliability); ISS Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (good reliability); KNN Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (good reliability); SARPY Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (good reliability)

# Suspected persistent in the environment: The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable

# Suspected skin irritant: The Danish QSAR database contains information indicating that the substance is predicted as skin irritant

Related composition

Related composition:

1-chloro-2-methylpropan-2-ol

1-chloro-2-methylpropan-2-ol

Classification

Physical hazards

Explosives

Reason for no classification:

data lacking

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Hazard category:

Flam. Liquid 3

Hazard statement:

H226: Flammable liquid and vapour.

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data lacking

Pyrophoric liquids

Reason for no classification:

data lacking

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data lacking

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data lacking

Oxidising liquids

Reason for no classification:

data lacking

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data lacking

Desensitized explosives

Reason for no classification:

data conclusive but not sufficient for classification

Health hazards

Acute toxicity - oral

Reason for no classification:

data lacking

Acute toxicity - dermal

Reason for no classification:

data lacking

Acute toxicity - inhalation

Reason for no classification:

data lacking

Skin corrosion / irritation

Hazard category:

Skin Irrit. 2

Hazard statement:

H315: Causes skin irritation.

Serious eye damage / eye irritation

Hazard category:

Eye Irrit. 2B

Hazard statement:

H319: Causes serious eye irritation.

Respiratory sensitisation

Reason for no classification:

data lacking

Skin sensitisation

Reason for no classification:

data lacking

Aspiration hazard

Reason for no classification:

data lacking

Reproductive toxicity

Reason for no classification:

data lacking

Effects on or via lactation

Reason for no classification:

data lacking

Germ cell mutagenicity

Reason for no classification:

data lacking

Carcinogenicity

Reason for no classification:

data lacking

1. Specific target organ toxicity - single (STOT-SE)

Hazard category:

STOT Single Exp. 3

Hazard statement:

H335: May cause respiratory irritation.

Affected organs:

other: high respiratory tract

1. Specific target organ toxicity - repeated (STOT-RE)

Reason for no classification:

data lacking

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Reason for no classification:

data lacking

Hazardous to the aquatic environment (long-term)

Reason for no classification:

data lacking

Hazardous to the ozone layer

Reason for no classification:

data lacking

Labelling

Signal word:

Warning

Hazard pictogram

GHS02: flame

GHS07: exclamation mark

Hazard statements

H226: Flammable liquid and vapour.

H315: Causes skin irritation.

H319: Causes serious eye irritation.

H335: May cause respiratory irritation.