1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-(C16-18(even numbered) and C18 unsaturated acyl) derivs., hydroxides, inner salts

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

June 27, 2017 - November 02, 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

- Analytical purity: 100% (UVCB)
- Purity test date: 06 June 2017
- Lot/batch No.: 180517GT41
- Expiration date of the lot/batch: 31 December 2017
- Appearance: Beige pasty solid
- Storage: At room temperature

Decomposition:

ambiguous

Remarks:

Reaction and/or decomposition of the test item was observed during DSC experiments starting at a temperature of 200°C

Decomp. temp.:

200 °C

Remarks on result:

not determinable

Remarks:

Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started

RESULTS

Preliminary test

Starting at 250°C, the weight of the sample decreased significantly. At 270°C, the sample weight had decreased by 25%. After the experiment, a dark brown residue was observed on the lid of the sample container and a brown molten residue remained in the sample container (original colour: beige). The change of the colour indicated reaction and/or decomposition of the test item.

Main study

An endothermic peak was observed between 100°C and 200°C. The endothermic effect was due to evaporation of volatile components (i.e. solvent, impurities). An endothermic peak was observed starting at 200°C. The effect was due to reaction and/or decomposition of the test item. After the experiment, a brown molten residue remained in the sample container (original colour: beige) and a brown residue was observed on the lid of the sample container. The change of the colour indicated reaction and/or decomposition of the test item.

Conclusions:

Reaction and/or decomposition of the test item was observed during DSC experiments starting at a temperature of 200°C. Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Executive summary:

The boiling point of the test item was investigated in a GLP-compliant study performed in accordance with EU Method A.2 and OECD Guideline No. 103, using Differential Scanning Calorimetry (DSC). Reaction and/or decomposition of the test item was observed during DSC experiments starting at a temperature of 200°C. Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Description of key information

The boiling point of the test item was investigated in a GLP-compliant study performed in accordance with EU Method A.2 and OECD Guideline No. 103, using Differential Scanning Calorimetry (DSC). Reaction and/or decomposition of the test item was observed during DSC experiments starting at a temperature of 200°C. Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Additional information

The boiling point of the test item was investigated in one GLP-compliant study performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and was selected as a key study for the endpoint.