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EC number: 200-370-5 | CAS number: 58-22-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
Description of key information
Valid experimental study (pretest type data) with use of a vapour pressure balance (Knudsen effusion method as described in EU testing guideline A.4). Analytical Development Physical Chemistry, Schering AG Berlin. Study report No. A05406 (ADP 2001_163), dated 2001-09-01.
Result: The vapour pressure of testosterone at 25°C is < 0.001 Pa.
Key value for chemical safety assessment
Additional information
The vapour pressure of testosterone was determined using a screening method based on the detection of the evaporation rate from a Knudsen cell of a vapour pressure balance at 25°C.
Testosterone was mixed with three other compounds. From all four test substances low or very low vapour pressures, based on the study directors experience were expected. For this reason the experiments consisted in the measurement of the evaporation rate of the mixture from a Knudsen cell at 25°C. Since the evaporation rate of the mixture was below the value derived from the lower limit of the vapour pressure range recommended for use of a vapour pressure balance (10-3Pa, EU testing guideline A.4) it can be assumed that the vapour pressure of the mixture is lower than 10-3Pa.
Considering this this fact, the vapour pressure of the single compounds in the mixture has also to be lower than 10-3Pa.
Therefore, the vapour pressure of testosterone can be estimated to be at 25°C :
p25< 10-3Pa
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